teapolyphenols (TPs) ????? (????)? flavandiols? flavonoids ?? phenolic ????? ??? ??? ??? ? polyhydroxyphenolic ???? ????? ?? ??? ???? ??? ????? ??? ??? ??? ???? ??? ???, ?????? ??? ????? ??? ? 60% ??? 80% ???. ?????? ???????? ???? ????????? ??????? ?????? ???? ?????? ???? ???? ???? ?????? ???? ?????? ???? ?????? ???? ?????? ???? ?????? ???? ?????? ???? ?????? ?? ?????? ??? 8 ????? ???? ?

??? ??????? ??? ??? ????? ?????? ?? ?????? ???? ???? ?????, ?????? ?? ?????? ??? ??? ????? ?????. ???? ???? ??? ????? ???? ?? ???? ?? ???? ??? ?? ??? ??????

??? ???? ??? ??? ????? ???? ?????? ??? ????? ???? ?? ????? ??? ?? ???? ????? ??? ?????? ??-?????? ??-?????? ??-???? ?? ??-???? ????? ????? ??????? ?????? ?? ???? ??? ??????????

????? ???, ??????? ???? ???? ???? ??????? ????? ?? ????????? ????? ?????? ?????? ?????; ?????? ?? ????? ????? ?? ????????? ?? ????? ??? ??????????-????????-??? ??? ????????? ????? ????? ?? ????? ??????? ?????? ??????? ???? ???? ????? ????? ?? ??????? ?????

???? ???? ??? ??? ??????? ????? ??????????? ????? ??? ?? ?????? ??????? ?????? ???? ???? ???? ?????? ???? ????? ??? ????? ?? ???? ???? ?????? ????? ??? ?? ?????? ???? ?? ?????? ??? ??? ????? ??? ????? ???? ????? ???? ?? ?????? ??? ??? ?? ?? ?????? ?????? ???? ??????? ?

?? polyphenols ???? 1.???? ?? ????? ?????

?? ????? ??? ???? ???? ??? ????, ???????, ????? ?? ???? ??? ??? ??? ?????? ?????????? ???? ???? ?? ??? ???-??? ??? ??? ???? ??. ?????? ???? ???????? ?50 ??? 60 ???? ?????? ??? ?15 ??? 20 ???? ???????? ?10 ??? 15 ???? ????? ?6 ??? 8 ???? ?????? ?4-6 ??? ??? ????? ???? ??? ???, ?? ?????? ??? ?? ??? ??? ????? ???, ???? ???, ???? ???? ?????, ? pH 2 ~ 7 ??? ?????; ??? ??????? ????? hygroscopicity ???? ?? ??????? ???? ??? ????? ??? ????

?? polyphenols ???? 2.?????? ??????

??? ?????? ??? ????????? ? ??-????? ?? ??-????? ?? ????? ?????? ???????? ???? ? EGCG ????? ??? ???? ???? ?? ???? ???-????? ??????? ?????? ?????? ??????? ????? ??? ????? ??? ??? ? phenolic hydroxyl ??? ?? ? ??? ????? ???? ????? ??? ????? ?????? ????????? ?????? ???? ?? ????? ??? ??????? ???? ??? ???? ??? ?? ????.

???? ??? ??? ??????? ??????

1.???? ??? ?? ???

??? ??????? ???? ??? ?? ??? ???? ??? ?? ??? ????, ???? ???? ????? ???? ?? ?????? ???? ?????? ????? ?? ??? ??????. ???? ????? ??? ??????? ??????, ?????? ????? ????? ?? ???? ??? ???? ??? ???? ??????.

2.?? ??? ?????????? ???

???? ????? ????? ????, ?? ????? ?? ??? ?? ??? ??-???-????? ??? ????? ??-???-????? ?????. ??????? ?????? ???? ??? ????? ??? ????? ??????? ???? ????? ??? ?? ???? ????? ???? ?? ?????? ???? ????? ??? ????? ???-?????? ?????? ?????? ??? ?? ???? ???? ??? ??? ?? ????? ?? ??? ????? ??????? ????? ????? ????? ???? ?? ??? ? phenol hydroxyl ?????? ????? ???? ????? ??? ??? ?? ??? ???? ????? ?????????? ?????

?? polyphenols ???? antioxidative ?? ?? phenol hydroxyl ???, ?????? ??? ??? ?? ??? ??? ???? ?? ???? ??? ??? oxidation ???? ????? ???, ?? ???? hydroperoxide ???? ????? ???? ??. ?????? ?? ? ????-???? ??? ?????? ???? ??? ?????? ???? ??? ???? ???? ???? ? ????? ?????? ??????? ??? ?? ???? ??? ???? ????? ???? ??????? ?????? ? phenol hydroxyl ??? ?? ???? ????? ??, ??? ???? ??? ???? ?????? ??? ????? ?? ????? ????? ?????? ?????.

3.Functional ???? ???

??? ??????? ?????? ??? ??? ??? ??? ??? ???? ? ?? ?? ???? ???? ?? radicals? ?????? ???? ??? ????? ?????? ??? ?????? ???? ?REDOX ??? ????? ???-??? ???????? ??? ??? ???? ????? ???? ????? ??? ????? ??????? ????? ????? ?? ?? ????? ???? ?? ????? ?????? ???? ??? ????? ?????? ??? ?????? ??? radicals ???? (scavening system) ????? ?? ?????? ???? ?????? ????? ????? ??? ion??? ?????? ??? radicals ???? ??????? ??? ????? ??? ???? ???????, ??? ?????? ???? ?? ????? ??? ???. ??? ???? ??? ??? ??? ?? ???? ?? ????? ????? ???? ?? ??? ????

??? ????? ?? ??? ????? ????? 4.??????

??? ???? ??? ?????? ??? ??? ?????? pseudomonas, Enterobacter, ??????? ?? ????? ??? ?? ???? ????? ??? ??? ???? ????? pseudomonas ??????? ???. ??? ??????? ????? ???????? ???? ???? ??? ???? ?????? ? ??? ?????? ????? ? ?????? ?????? ? ???? ??? ????? ?? ??? ????? ????? ??????

???? ???? ??? ?? ????? ???? ?? ? ??? ?? ? ??? ?? ?? ??? ??? ???? ?? ????? ??? ????? ? ??? ? ??? ??? ?? ???? ?? ??? ??? ??? ???? ??? ???? ???? ?????? ? ?? ????? ??? ??? ??? ??? ???? ???? ??? ?? polyphenol ??? ???? ?????, ???? ?? ???? ?? ??? ???? ??? ?????? ?? inhibition ???, ??? ?? ?? polyphenols ?? ???? ???? ?? ???? ???? ???????? ??????, ?? ??? ?????. ?? ????? ??? ???? ???????? ???? ??? ???? ????? ???? ??? ??????

5. ??????? ???? ??? ??? ?????

????? ??? ?? ?? ??? ??? ?????? ????? ??????? ??????? ??? ???? ???? ????; ??? ????? ???? ???-?????? ???? ???? ??????? ???? ?? ??????? ??????? ??? ????? ?????? ????? ??????? ?????? ????? ??????? ???? ?????? ????? ???????? ?????? ??, ?? polyphenol ?????? ???? ??? ????? ?? ????? ? ??? ????? ?????, ???? ?? ????? ??? ????? ? ?? ?????? ??? ?????? ???? ???? ???? ??? ?? phenolic hydroxyl ????, ??? ????.

??? ?????? ???? ?? ????? ??? ????? ??? ?????? ???? ???? ?????? ????? ??? ?? ?????? ??????? ??? ???? ????? ????? ??? ????? ?? ????? ??, ?? ???? ?????? ????? ????? ?? ?????? ????? ???? ???. ??????, ?? polyphenols ??? ?? ?? ????? ??????? ?????? ?? ???????? ???? ??????, ?????? ???? poslerodnыh posleduet ????. ??? ??? ?? ????? ????? ??????? ?????? ???? ?? ????? ?????, ?? ?????? ??? ?? ????? ???? ?????? ????? ????? ???, ??? ???? ???? ???????.

?????? ??? ??? ??????? ?????

1, ??-????? ?? ??-???

?? ???? ????? ????? ?????? ?? ?????? ??? ???? ???-????????? ??? ??? ??? ??? ??? VC? VE ?? ?????? ?????????? BHT? BHA ?? ?????? ?????? ?????????? ??? ??? ??? ?????? ?? ?????? ?? ??? ??? radicals? ??????????? ??? ?????? ???? ?? ????? ??????? ????? ?????? ??? ??? ?? ???? ????? ?????? ?? ??-??? ????? ???? ????????? ?? “??? ?????” ????? ??????

2.Hemostatic ????

??? ????? ??-????? ?? ??-????? ???????? ????? ???? ?? ?? ????? ????? ?? ?????? ????? ?????? ? ????? ??? ??? ??? ?????? ?? ???? ?????? ?????? ? ?? ??? ???? ?? ??????? ???? ?? ??? ????? ????? ????? ???? ?? ?? ?? ?????? ??? ???? ??????? ?????? ?? ????? ??? ?????? ?? ????? ??? ???? ????? ????? ?? ????? ??? ??????

3.Antitumor ????

??? ????? ???? ????? ?????? ??-????? ?? ??-???? ?????? ????? ????? ??????? ???? ??????? ?? ????? ??? ??? ??? ???? ?????? ??????? ????? ?? ????? ????? ??? ?????? ????? ????? ?? ??? ?????? ?????? ?? ???? ???? ?? ?? ??? ?????

4, ??? ????? ????, ??????????? ??????

?? ????? ????? ?? ???? ??? ??????? ??? ????? ????? ??? ??? ???? ? ???? ????? ???? ?????? ??? ??? ? atherosclerosis ????? ?? ???? ????? ???? ???? ???? ?????? ???? EGCG ?? ??? ????? ????? ???? ??? ?????? ??? ??? ?????? ?????? ???? ??????? ??????? ??? ????? ?? ????? ????? ??????? ????? ????? ?????? ?? ?????? ????? ??????

5. ?????????? ??? ?????

?? ????? ??? ?? ??? ?? (cardiovascular) ????? ?? ?? ?????? ?? ????? ??? ???, ????? ????? ??????? ?? ?????????? ??? ????? ??????? ??????????? ??? ?????. ?????? ?? ????? ??? ???? ????? ?? ????? ?? ??? ??? ???? ???? ????? ???? ????? ?????? ????.

6.Anti-oxidation ?? ??-????

?? ????? ??? ??? ??? ???? ??? ??? radicals? ?????? ?? ???? ??? ????? ?????? ??? ????? ???-??? ??? ? VE ???? ???? ??, ?? ? VC ?? VE ?? ???? ???? ??.

7.Caries ?????

?? ????? ?????? ?????? ????? ??? ?????? ?? ????? ?? ??????? ?????? ???? ??????? ???????

8. ??-????? ?? ??-????

?????? ???? ????? ?????? ?????? ?? ???? ????? ??????? ??-????? ?? ??-???? ??? ????? ??? ?????, ???? ??? ??? ??????? ??? ??? ?? ???. ????? ??? ??? EGCG ??????? ???? ??? ?? ????? ?? ????????? ????? dihydrofolate reductase ????? ?????? ??? ?????? ?? ???? ?????, ???? ???-????? ???? ????.