??? ??? ??? ????? ??? ?? ????? ????
???? ??? ??? ?? ??? ???? ??? ??? ??, ?? ?????? ??? ??? ???? ??? ?? "??? ???? ????" ??? ????. ?? ??? ?? ??????? ??? ???? ?? ??? ???? ????? ???? ??? ??? ???? ???
???? ????? ????-
????? ?????? ????;
?????- ????? ??? ???? ??? ??? ???? ?? ???? (100% ???) ?? ?? ??? ???? (??? ??? ??? ?????) ?? ?????? (??? ??????? ?? ??) ????? ???? ?????? ??? ?? ???? ??? ??????
????? ??? ???? ???????? (???? ????? ???) ???? ????? ??? ??? ?????? ???? ????? ??? ???? ???
???? ????? ???? ? mannose ????? ????? ??? ????? (???? 20% ??? ??? ??? ??) ??? ??? ???
?????? ?? ??????? ?? ??? ??? ??? ????? ???? ????? ?? ????-6-???? ??? ?????? (?????? mannose kinases) ?????
?? ?????-6-???? ?????- ????-6-???? ????? ?? ?????-6-???? ?phosphomannose isomerase ??????
?? glycolysis ???? ?????- ?????-6-???? ? glycolysis ???? ??? ???? ????? ??? ??? ??? ??? ????? ???? ???? ????? ??? ??? ?? ?????? ??? ??? ?????? ?? ????-6-???? ?? ??? ??????? ????? ??? ?????? ???? ?? ?????? ?????. .
?????? ???? ???????;
?
???? ?? ??? ??? ???? ?? ????? ????? (???? ??? ?? ?? ??? ????? ?? ????? ??????? ?????? ?????) ???? ?? ???? ??? ???? ????? ?????? ????? ??? ???????? ??? ???????? ???? ??? ????? ????? ??? ??? ??? ????? ?? ?????? ??? ???? ??????.
????? ?? ???? ??????;
?
???? ??? ?? ? 2 ???? ???? ?????? ?? ????? ??? ???? ???????? ???????? ???? ??? (??? 0.2 ? / ?? ????? ???? ? 70 ?? ??? ?? ? 14 ??? ?? ??? ??), ??? ??? ???? ??? ??? ??? ????? ??? ?? ???? ??? ?????.
?????? ?????? ?????? ???????? ???? ??? ??? ??? ??????.
???? ??? ??? ?? ??? ???? ???????? ?????? ???? ????? ????.
?
???? ????? ????- ????? ?? ??? ????? ???? ?????? ?? ???? ??? ?? ????? ??? ????? ????? ????? ???
?? ??????? ????? ?????? ??? ????? ?? ????? -6-???? ???? ??? ?????? ????? ???? ????? ?? ?? ??????? ??? ???? ? ??? ??? ??? ???? (????) ???? ????? ???????
??????? ??????- ??? ??? ??? ???? ??? ???? ??? ????? ?????????? ???? ??? ?????? ??? ???????
??? ??????-
?
????- ??? ??? ???????? ????? ?????? ???? ??? (???? ?? ???? ?? ?????? ??? 1-2 ??? ????) ?? ????? ????? ???? (??? 0.2?/??) ?? ?????? ???? ???? ???, ??? ??? ???? ??? ????? ?????? ????? ???? ????, ??? ?? ?????? ?? ??? ??? ??? ?? ?????.
?????? ????? ????? ????? 70% ??? ??? ??? ?? ????? ?? “???? ????? ??? ??? ???” ??? ????? ??? ??? ???? ???? ??? ?????? ?? ????? ??? ???? ??? ??? ?? ??? ?? ??? (??? ???) ??? ????? ???? ?????? ?????.
?? ?????: ???? ??, mannose ?? ????? ????? (?????? Escherichia ???) ??? ???? epithelial ????, ????? ?? ???? ???? ?????? (UTIs) ???? ???? ??? ?? ??? ???? ??? ?? ?????? ??. ??? ??? ??? ???? ???? ????? ???? ?????? ??? ??? ??? ???? ????? ??? ???? ??? ??????? ????? ???? (????? ???? ?????? ??? ???? ?????) ???????? ????? ????? ??? ???????
????? ????? ?? ?????? ?? ????: ??? ???? ?????? ???? ??? ??? ???? ???? ??? ??????? ?????, ?????? ???? ????? ??? ????. ??? ???? ??? ??? ??? ?????? ????? ?????, ????? ??? ??? ?????? ??? ??? ???? ???? ??.
??????-
???? ???? ??? ??? ????? ????? ????? ??? ?? ?? ??? ?????? ????? ??????? ???? ??? ??? ??? ???? ??? ?????? ??????? ?????? ???? ??????? ?? ??? ??? ??? ??? ???? ????? ????????? ??? (??? ???? ??????) ???? ???? ????? ????? ???? ?? ??????? ?????? ??? ?? ??? ???? ????? ????? ???????