????, ??? ?????? ?? ????

????, ?? ??? ??? ??? ????? ??? ???. ?? ???? ? ??? ??? ?? ???? ???? ???????? ????. ??? ??? ???? ? ???? ???? ??? ???? ???? ? ? anhydrous ???? ??? ?????? ?? ??? ???? ?? ??? ?? ??? ??? ??? ?? ??? ????, ?? ??? ???, ????????? ?? ???? ??? ??? ?????? ????? ?????? ???? ???? ??????? ?? ????? ?? ???? ????.

????

???? ?????

?????

1. ?? ??? ????? ?? ??? ??? ??? ?? ??? ????, ????? ????, ????????? ?? ???? ??? ??? ?????? ???? ???? ???????? ?? ????? ?? ???? ????.

2. ???? ?????? ???? ??? ??? ??-??? ?? ??? ???? ????? ?????????? ???? ??? ?? (cardiovascular)? ???? ??? ?? (cardiovascular)? ???? ??? ?? (cardiovascular)? ???? ??? ?? (cardiovascular)? ???? ??? ?? (cardiovascular)? ???? ??? ?? (cardiovascular)? ???? ??? ?? (cardiovascular)? ???? ??? ?? (cardiovascular)? ??? ?? (cardiovascular)? ??? ?? (cardiovascular) ?? ??? ????? ??? ?? ???? ?? ?????? ?????? (??-???)? ???????????? ?????? (IDUR)? ?????? (BUDR)? ?????? (FUDR) ?? ??? ?????? ??? ?? ???? ????

3. ??-?? ??????? ????? ??? fluorouracil deoxynucleoside ?? iodoside ??? ?? ????.

????2

???? ????

???	?????	????
????	?? ??? ??? ???? ?? ???; ?? ????, ??? ????.	?? ???; ?? ????, ??? ????.
???????	≥95.0%	99.3%
???	7.0 ~ 8.5	7.4
????? ?? ???	??? ?? ??? ???? ??? ????	?????
??? ??? (KF)	≤26.0%	12.7%
??? ????	≤0.001%	?????
??? ??	≤0.00015%	?????
???? (HPLC)	≥98.0%	99.8%
????(UV)	≥97.0%	98.9%