????? ??????? ???? ??????
??????? ??????? ??????? ????? ???? ??????? ??????? ?? ???? ?????? ?????? ??????? ?????? ???? ?????. ?? ????? ??????? ???????? ????? ??????? ??????? ?????? ?? ????? ????????? ?????? ??? ??????? ?????? ???????? ???? ??????? ???? ??????? ????? ??????? ???????. ??????? ???? ?????? ????? ??? ???? ???? (??? ???????? ??????? ??????? ???) ????? ????? (??? ??????? ????? ??????). ????? ???? ?????? ????? ??????? ?? ????? ???? ??????? ????? ????? ??????? ???? ?????? ??? ?????? ???? ???????:
1) ?????? ???? ?????? (???????): ??????? ????? ??????? ???????? ?????????? ???????? ?????????? 2-????????-3-????? ?????????? ????? ??????? (2-?????-3-?????)? ????? ?????????????? (MCP)? ???.
2) ????? ??????: ???????? ???????? (MSG)? ??????? ???????? (IMP)? ???????? ???????? (GMP)? ??????? ???????? + ???????? ???????? (I+G)? ??????? ????? ???????? (MSS)? ??????? ????? ???????? (DSS)? ???.
3) ?????? ??????? ???????? ???????? ????????: ??? ??? ?????? ????? ?????? ???? ?????? ??????? ?????????? ?? ??????? ???????? ?? ????????
4) ?????? ??? ??????? ??????? ?? ????? ??????: ??? ?????????? ?? ????????? ????????? ??????? ?? ????? ????? ????? ???? ?? ??????? ???????????
5) ??????? ???????? ???????? ??????: ??? ????? ???? ????? ?? ???? ??? ??????? ??????? ??? ???? ??? ?????? ?????? ???? ????? ?? ???? ?????? ???? ????? ??? ???? ??? ???????.
????? ???? ???? ?????? ???????? ???????:
1) ?????? ?????? ?????? ????? ??????? ?????
2) ?? ?? ???? ???? ??????? ???? ?????? ??? ???? ???? ?????? ?????? ??????? ??????? ???? ???? ?? ???? ??????? ??????????? ???????? ?? ????? ????? ??????? ?????? ???????? ?????? ?????? ?????? ??????? ??????? ?????? ??? ????????? ????????
3) ????? ???? ?????? ??????? ?????? ?? ????? ?????? ???????? ?????? ?? ???? ????? ??????? ???? ????? ???????? ????? ????????
4) ??? ????? ?????? ??? ??? ????? ?????? ????? ?? ??? ????? ????? ????? ???? ??? ???? ????? ?????? ??????? ?????? ???? ?????? ????? ???????
5) ??? ?????? ?????? ??? ???? ?????? ????? ????? ?? ?????? ?? ???? ???? ?? ????? ???????? ?????? ???? ????? ????? ??? ?????????? MCP? ??? ??? ????
?) ???? ???? ???????? ??? ???????. ??? ?????????? ?? ???? ??? ??????? ?????? ?????? ??? ????????? ?????? ?????? ??? ???????? ???????? ??????? ???? ????? ????? ??? ??????? ????? ????? ??? ????????? ?????? ?????? ??? ?????????? ?????????? ?MCP? ???.
7) ???? ??????? ??????? ??? ?????? ???????? ??????? ?? ??? ????????? ????.
????? ????? ?????? ?? ?????? ???? ??????
?? ??? ?????? ?????? ??????? ?????
(?) ???????? ???????? ?????? ?????? ?? ????? ?????? ????? ?????. ?? ????? ????????????? ?????/????? ?????? ???? ????? ??????? ???? ?? ????? ?????? ?? ???? ?????? ???? ???? ?????? ?? ??????? ??????? ????? ????? ?????? ?? 1% ??? 20% (???? ??? ??? ???? ???? ??????? ?? ??????? ???????? ????????). ???????? (??????? ?????)? ????? ??????? ????????? ???????? ???????? ????? ????????? ??? 2-????? ???????????? ?? ????? ???? ???? ??? ??????? ???????? ????? ????? ?????? ????????? ??? ???????? ??????? ??? ???? ????? 93 ???? ?????. ???? ???????? ???????? ?? ?????? ??????? ???? ???????? ?????????. ??????? ?????? (Vetol2plus)? ??????? ????????? ???? ??? 2-????? ???????????? ?? ????? ?????? ??????? ????? ?????? ?? ??? ??? ???? ?????? ?????? ???? ?? ????? ????. ?????? ???? ??????? ?? ????? ?????????? ??????????? ?????? (PG) ??? ???????? ??? ?????? ?????? ??????? ??? ?????????: 1) ?????? ????? ??? ????????? ???????? ???????? ????????? ???????? ????? ????? ???? ???? ??????? ?????? ??????? 2) ?? ?? ?????? ???????? ???? ????? ????? ??????? ?????? ???? ?? ?? ?????? ???????? ??? ????? ??????? ???? ???? ?????? ????????? ???????? 3) ???? ????? ????? ??????? ?????? ?????? ????? 3-8 ???? ?? ????????? ????? ????? ?????? ??? ??????? ?????? 4) ??? ?? ???????? ?? I + G ?MSG ?MCP ?????? ?????? ??????? ?????? ????? ???????.
(?) MCPMCP? ??????? ????? ???? 3-?????-1? 2-?????????????? ?? 3-?????-2-????????-2-??????????-1-??? ?? ????? ????? ???? ?? ???? ???? ?? ????? ???? ????? ?????? ???????? ????? ????? ????? ?????? ????????. ??? ???? ????? ?? ??? ????? ??????. ????? MCP ????? ???? ?????? ???????? ???????? ??????? ???? ??? ??? ???? ?????? ?????. ?? ?? ???? ??????? ?????? ????? ?????? ???? MCP ????? ?????? ??????? ?? ???? ????? ???? ?????? ???? ??? ?????.
(3) ???????? ?????????? ??????? ????? ???? ????????? ??????? ?? 2-??????? ????? ?????????. ????? ???????? ?????? ?????? ??????? ????? ??????? ???? ??????? ???? ??? ????? ?????? ???????. ????? ?????? ???????? ????????? ?????? 1% ???? ?????? ??? ??????? ?????? ????? ???? ?? ?????? ?????? ?????? (??? ?? ????? ?? ??? ?????)? ??? ????? ??? ???? ??????. ??? ????? ????????????? ?????/????? ?????? (GC/MS) ???? ????? ?????? ?? ???? ????? ????? ?? ???????? ?????????? ??? ???? ?????? ?? ??????? ??? ???????? ????????? ??????? ????? ????? ?????. ?? ????????? ??????? ????? ???????? ????????? ??? ???? ???? 1%? ?? ????? ??? ???? ?????? ????? ?????.
(4) ?????????? ?????????) ????? ????????? 2? 5-????? ?????-4-????????-3 (2H)-???????? ?? ???? ????? ???? ??????? ??????. ?? ??? ???? ?? ??????? ????? ??????? ?? ?????? ???? ?? ???????? ?????? ????? ????? ??????? ???? ???? ???? ????? ??? ????????. ????? ????????? ?????? ?????? ???? ???????? ?????????? ????? ????? ???? ????? ???? ??????? ?? ????? ?????? ?????? ?????? ????? ?? ???? ????? ???? ??????? ????????? ??? ????? ??? ?????? ????? ??? ??????? ???. ????? ??? ???? ?? ????????? ?? 5.5 ??? 6 ????? ?? ????? ?????? ?16 ??? 20 ????? ?? ???????? ?? ????? ??????? ???? ??????? ???????. ?? ????? ????????????? ?????/????? ?????? ???? ????? ??????? ?? ????? ?? ???? ?????????? ????? ?? ??? ????? ??? 5? ?? ???? ??????. ?? ????? ????? ???? ????????? ????? ?????? ??????? ????? ??????? ??? ?????? ?? ???????? ????????? ???????? ????????? ????? ???? ?????? ???? ???? ??????? ?? ????? ???? ????? ???? ?? ??????? ??????????. ?????? ???? ???? ?????? ??? ????? ????????? ??? ????? ?????? ????? ???? ???? ?????? ?????? ????????? ?????? ???? ??????. ??? ????? ????? ????????? ??? ????? ????? ?????? ?????? ??????? ???? ?????? ????? ?? ????? ?????? ???????? ??? ???? ??? ????? ???? ??????? ???????. ???? ?????? 1 ????? ??? ????????? ????????? (I + G) ?MSG.
(5) ???????? ?????? ?????? ??? ????????? ?????? ?? ????? ?????? ??????? ??: 2-?????-3-????? ?????????? ????? ??????? (2-?????-3-?????)? 2-?????-3-?????-?????????? 2-?????-3-????? ?????????? ?????????? ???. ????? ????? ?????? ??? ????? ?????? ??????? ???????? ???? ???? ??????? ???????? ?? ???? ????????? ??? ?????? ????? ????.
?????? ??? ???? ??????
(?) MSGMSG ?? MSG? ???????? ????? ???? L-???????? ????????? ?? ???????? ????????. MSG ???? ???????? ??? ????? ??????? ???? ??????? ????? ?????? 0.014%. ???? MSG ??? ????? ?????? ???????? ??? ????? ????? ??? ??? ?????? ?????? ?? ??? ??????. ??? ???????? ???? ??????? ?????? ?????? ?? ??????? ???????? ??? ???? ?????? ?????.
????? MSG ??????? ??????? ?? IMP ?GMP ?(I + G). (MSG + IMP) ??? ????? ???? 0.05 ?/???? ?????? ???? MSG∶IMP = 1∶1? ??? ??? ???????? ??? ???? ????? ?? ???? MSG ?IMP? ???? ?????? ??????? ?? IMP ?? ??? ??? 50%? ??????? ???? ?? ??? ????? ????. ???? ?????? ??????? ?? IMP ?? 50% ??? 100%? ??????? ???? ?? ??? ????? ????.
?????? ?? ??? ??? MSG ?? (I + G) ?????? MSG ???? ????? ????? 99% MSG + 1% (I + G) ?????? ?????? ????? ????? 98% MSG + 2% (I + G) ?????? 3.5 ???? ????? ????? 96% MSG + 4% (I + G) ????? 5. ?? ????? ???? ??????? ?????? ?? ??? ??????? MSG ?? (I + G)? ????? ??????? ?????? ?? ?????? 1.
(2) IMP ?GMP ?(I + G): ???? IMP ?GMP ?????? ????? ?? ?????? ??????? ???????? ??? ??? ????? ???? ??????? ???????? ?????????? ??????? ??? ??????? ????????? ??????? ???? ?????? ?????? ?????? ???????? ???????. ????? IMP ?GMP ????? ?????? ????? ?????? ?????? GMP ???? ????? ???? ??????? ?? IMP? ?????? ?? ??????? ???? ????? ??????? (?? ?? I + G ?IMP ?GMP ?????? 50% ??? ?????). ???? ?? MSG ?IMP ?GMP ?(I + G) ?? ???? ???? ????? ???? ????? ???????? ????? ????? ???? ?????? ?????? ??? ?????? ??????.
(3) MSS ?DSSMSS? ????? ???? ?? DSS ????? ?????? ?????? ??? ????? ??????? ???? ?????????. ????? ????????? (??? ??????? ???????? ????????? ??????????? ???? ?????? ???????? ??????) ?? ???????? ???????? ????? ????????? ????? ????????? ???????? ????? ????????? ???????. ????? ?????? ?????? ????? ?? MSG.
3. ??? ???? ????? ?? ????? ??????
??? ?????? ?? ????? ?????? ?????? ?????????. ????? ?????? ??? ?????? ??? ?????? ????? ????? ????? ??? ????? ??? ??? ???? ?? 10 ????? ?? ?????????? (??? ???????????? ???????? ?????????????? ?????????? ?5-????? ????????? ???)? ??????? ?? ????????? (?????? ???????? ???) ????? ?? 10 ????? ?? ?????? ??????? ??????. ??? ???? ??? ????? ??????? ????? ??????? ??????? ??????? ???? ????. ??? ?? ??? ??????????????? ?????????? ???????????? ??????????? ????????? ??????????? ??????????? ???????????? ????????????? ??????????? ????????????? ?????????????? ??????????? ???????????? ???????????? ??????????????? ????????????? ?17 ??? ???? ?? 208 ???? ?????. ????? ??? ?????? ???????? ?? ?????? ?????? ?????? ???? ????? ??? ???????. ??? ????? ????? ??? ?????? ??? ???? ?????? ???? ???????? ?????? ???? ????? ????? ??? ?????? ??? ???????? ??? ???? ??? ???? ????? ??????. ?? ??? ?????? ???????? ?? ???? ?????? ???????? ???????? ????? ??? ?????? ?????? ?????? ??????? ??? ???? ?? ?????? ??????? ??????. ???????? ??? ??????? ??? ?????? ???????? ???? ????? ??????? ???? ??? ??????. ????? ???? ????? ??? ?????? ??????? ????? ?? ??? ?????? ??????? ???? ?? ??? ??????? ???????? ???? ?????.
??????? ????? ?????? ?????? ?????? ??????
??? ?? ??????? ?? ??? ????? ?? ??????? ?? ?????? ?? ????????? ??? ???? ??????: 1) VB1 → ????? ??????? (2-?????-3-???????)? 2) ????? ???? ????????? + (NH4) 2S →H2S? ???? 3) ?????? + (NH4) 2S →H2S? ???? 4) ??????????? ???????? ???????? + (NH4) 2S →H2S? ???.
?????? ????? ???? ?????? ?????? ????? ???????? ????????? ?? ??????? ????? ??????? ???? ??????. ?? ???? ?? ?????? ???? ????????? ?????? ???? ??????? ?????? ?? ?????? ????????? MSG ?(I + G) ?????????? ????????? ???????? ?????? ?????? ?????? ?? ????? ??????? ????? ?????? ????????? MSS ?DSS ???? ????????? ???????? ??????? ??? ?????? ???? ??? ??????? ?????? ???? ??????? ?????? ?????? ?????? ?????? ???? ?? ???????.