(1) ??????? ??????? ????????

???? ????? ?????? ???? ??????? ?? ???? ?????? (0.7-1.2%) ????????? (0.3-0.8%). ????? ???????? ?? ?. C?H??O? ??. ?8. ????? ????? ????? ??? ???????? ???? ??????? ??????? ??? ???? ????? GLUT1? ????? ?? ?????? ???? ????? ?????????? ??? ????? ????? ?????? ????? ????? ????? ?????? ?78.

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(2) ???? ?????? ?????? ?????

?? ??? ????? ????? ?????? ??????? ????? ???? ???????? ?? ???????? ????? ????? ??? ?????? ?????? ?????? ???? ???? ??????? ?????? ??? ???? ??????? ????? ??????? ??. ??? ?????? ?? ???? ????? ???? ???????? ?? ??????? ?????? ?? ?????? ???????? ??????????? ???????? ??? ?-?? ????? ???? ??? ????? ??? ?????? ???????? ????? ???????. ??? ??????? ?? ?? ???? ?? ?? ????? ?? ???????? ??? ????????? ??????? ?? ????? ?????????.

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??????? ???? ??????? ?????? ???????

(?) ?????? ??????? ????? ??????? ???????

???? ???????? ???????? ??? ?? ????? ?????? ?? ??????? ?????? ???? ?? ???? ?? ????? ???????? ??????? ??????? ??? ?????? ????? 38%. 8 ????? ???? ???? ?? ???:

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? ??????? ??????? ?: ??? ????? 90% ?? ??????? ?? ???? ???? ????? ?? ???? 30-60 ?????? ???? ????? ????????? ??????? ??????? (??? ????????? ?????????) ?? ????? ?8?

????? ??????? ???????: ????? ??????? β-1? 4-???????? ??????? ??????? ?????????? ?????? ????? ???????? ??????? ??????? ????????? ?????? 3 ???? 78?

? ????? ??????? ?: ????? ????? ?????????? ?????? ??????? ???????? ?????????? ?????? ??????? ??????? ?8.

(2) ?????? ??? ?????? ???? ???????

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(3) ???? ??????? ?? ??????? ??????? ???????? ?????

??? ??? ????????? ????????? ????? ??????? ??? ???? ???? ????? ?? ???? (GI) ???? 0? ???????? ??????? ?? ????????? ???? ?? ???? ??? ???? ??? ?????? ?????? 2.1 ??????/??? ??? ???? ?????? ?78. ????? ????? ????? ?? ???? ??????? ??? 2024 ?? ??????? ???? ??? ???? ???????? ??? ?????? ????????? ????????? ?7 ?? ???? ????? ???? AMPK.

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3. ????????? ???????? ?? ????? ???????

(1) ????? ??? ????? ??????? ????????

??????? ????? ??????? ???????: ?? ????? 500 ???/????? ?? ????? ????????????? ??? ????? ???? ????? ????? ?? ????? ?????? ?????? ?????? ??? ???????? 2 ????? ???? ?? ????? ????? ?? ????? 7?

? ???? ?????? ?? ????? ?: ????? ??? ???? ??????? ????? ?? ???????? ????????-????????????? ??? 45% ?????????? ??? ????? ???? ????? ???? ?7?

? ????? ??????? ??????? ?: ???? ?????? ????? ?????? ????? ??????? ?? ???? ???? ?????? ????????? ????? 18%? ??? ?? ??????? ?? ???? ????? ????? ???? ??????? ????? 30% ?7.

(2) ????????? ?? ?????? ????????? ????????

??? ????? ????? ?????? ?????? ???????? ???????? ???? ?????? ????? ????? ???? ????? ?????????? ???????? ?? 58% ??? 92%? ?????? ????? ??????? ????? 40%7. ??? ??? ????? ????? ??????? ?????? ??? ????? ???? ??????? ??? 60 ????? ??? ???? ????? 120 ???? ?????? ????? ???? ???????? ?? ???? ?????.78

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4. ??????? ?????? ???????? ????????

(1) ??????? ??????? ?????? ?? ??????

? ?? ?????? ?: ?? ?????? ??????? ?????? 3 ????? ???? ?????? ?? ??????? ?????? ?? ???? 5 ????? ??? ???? ??????? ?? ?????? ??? ?????? ????? ???????? (???? ????? ????? 7?) ?8?

? ????? ??? ??????? ?: ????? ???? ????? ???? ?????? ?????? ????? 50?? ???? ??????? ?8 ??? ????? ???????

? ???? ????? ?: ??? ???????? ?? ?????? ????? ?????? ????? ??????? ?????? ????????? ?????? 2.3 ??? ?8.

(2) ???? ????? ?????? ???????? ????????

????? ??????? ?????? ???? ???????? ???????? ??? ??????? ??????? ??????? ??? ?? ??????? ?? ??? 2024? ?? ???:

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??? ??? ????? ?????? ??? ??????? ?? ????? ???????? ???? ??? ???? ?? ??????? ????? "??????" ?7?

??? ??? ????? "??? ?????? ??????? ??????" ??? ??????? ???????.

??? ??? ????? "?? ???? ??????? ?????? ??????" ??? ?????? ≥1 ??/100 ??.?7.

1. ???????? ??????? ??????????

(1) ???? ?????? ??????

? ????????? ????? ????? ???? ???? ???????? ?: ????????? ????? ????? ??????? ??????? ????? ?? 5 ????? ??? ????????? ??????? ??? ????? ?7?

? ???????? ?: ?? ??? ???? ????? ?????? ???????? ???? ??????? ???????? ?????? ???? ?????? ????????? ?7?

? ??????? ??????? ??????? ?: ??? ?????? ?? ????? ???????? ??? ????? 30? ?? ????? ???????? ?????????? ??? ?? ???? ??? ?????? ????????? ?7.

(2) ????? ?????? ??????????

? ????? ????? ?: ????? ?????? ??????? ?????? ??????? ?????? ?8?

? ??????? ?????? ?: ?? ????? ????? ???????? ???????? ????? CRISPR? ??? ??? ????? ???????????? ?? 60% ??? 85%?7?

? ?????? ???? ?: ???? ?????? ?????? ???????? ??????? ????? ??????? ?? ????? ?? ????? ?????? ?????? ??? ???? ???? ?8.

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??????? ?????? ??????? ????????????? ?? ????? ??????? ??????? ???????? ??? ???? ?????? ????? ?? ?????? ?????? ????? ??? ????? ??????? ???????. ??????? ?? ?????????? ????? ?????? 2030? ????? ??? ??????? ??????? ?????? ?????? ?????? ???? ??? ????? ????????? ????????. ??? ???? ?? ??????? ????? ?? ????????? ?????? ??? ????? ????? ??? ?? ????? ??? ???? ????? ??????? ??? ???? ???? "????????? ???????? ???? ?? ??? ????": "??? ???? ????? ???????????? ????? ??????? ??? ????? ??????? ??? ?????? ???? ????? ???????".