????????? ??????? ????????? ??????, ??????? ????????????? (SAIB) ?????????? ????????? ?????, ???, ???????? ??? ????? ???????? ???? "????? ????????" ???? ?????, ?? ????? ????????? ????????? ??? ??????? ????????? ?????? ???? ????? ?????, ??????????? SAIB ????? ?.? ??????? ??????? ???? ???????? ???? ??? ??? ??? ?????, ?? ?.?% ?? CAGR-? ?????? ?????

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??. ????? ?????: ?-?????????????? ?????? ??? ??????????? ??????? ?????? ??????????? ?

????? ???? SAIB-?? ??? ????? ?? ?? ???????????? ??? ???????????? ?????????? ???????? ?????? ?????? ????, SAIB ??????????? ??? ? ????? ??????? ??? ??????? ????????? ??? ???? ???? ??????? ????? ????????? ???, ???? ???????? ?????????? ???????? ????????? ??? ????????? ??? ??? ????? ??? ?????? ???? ? 2024 ????, ??????????? ?????? ???????? ????-???? ???????? "???? ????????? ????????? ???????" ?? ???? ????? ???? ???, ?? ?????????? ???????????? ??????????? ???? SAIB ??????? ???? ????? ????? ??????? ???? ?

?

CODEX Alimentarius Commission (CODEX) ?? ??????? ??? ???????, ?????????? ???????? SAIB ?? ???????? ??????????? ?????? ?? 70g/kg (?????? ???????? ????????, ?????? ?????? ????? 0.14g/kg), ??? ?? ????????? EU-?? EFSA, ??????? ?????????????? FDA ??? ???? ????????? ??????? ??? ???????????? ??? ??????

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?2. ??? ?????: ?????-???????? ?????-?????? ??????????? ??????? ??????? ?

??????? ????????, SAIB-?? "?? ??????? ????? ??? ???? ??????????? ?????" ????????????? ?????? ?????? ?????? ?????? ???? ????? ?????? ????, ?????? ??????? ?? ???????????? ???? ?? "Risperidone Long-acting microsphere storage System based on SAIB" ???? ???? ?????????? ?????? ???, ?? ??????? ???????????????? ????? Risperidone-?? ?? ???? ????? ?????? ?? ???? ??????????, ???? ????? ??? ?.??% ? ???????? ??? ?????????? ??? ?????? ??????? ??????????? ??% ??? ???? ????? ?????? ?? ????? ?????? ?????? ??????? ????? ?????? ????????? ???????? ??????????? ?????? ??????

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???????, ???????? ???????????? ??? ????? ????????????? ??????????-????? ?????????? ???????? SAIB-?? ?????? ????????? ??? III ???????? ???????? ?????? ?????? ?????? ???????? ????????? ?? ????? SAIB-??????? ???? ???????? 2026 ???? ?????? ???? ??? ??? ??? ?????, ??? ??? ??? ??????? ???? ???? ????? ????? ??????

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?. ???????? ??? ???????? ???????: ?????? ??????? ??? ???????????? ??????? ???????

SAIB ?????????? ????? ?????? ?????? ??? ?????? ?????? ??????? ??? ?? ?????? ????????????? ????????? ??? ?????????? ??????????????? ?????? ???? ???? ????? ????? ????, ????? ????????? ????????? ??????? "?????-??? ?????" ???????? ???? ???, ????????????-??????? ????? ?????? ???????? ???????? SAIB ??????? ???, ???? ???????? -??°C ???? ??°C ??????????? ??????????? ????? ????? ????, ??? ???? ???????????????? ??????? ??% ? ????? ?????

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?????????? ????????? ?????????? ????????, SAIB-?? ?????????, ??????? ??????? ???????? ??? ???????? ???????????? ????? ???? ???? ???? ?????? ??????? ??? ???? ?? ???-????????? ????????? ??????? ????????? ???? ???? ?? 0.5% SAIB ???????? ?? ??? ???????? ?????????? 90% ??? ???? ????????? ?????????? ?????? ???? ???? ??? ????? ???? ??????????? ??? ???

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? ???, ??????????? ???????: ???????? ?????????? ??? ????? ?????????? ????? ??????? ????????? ?

??. ???? ???????? ????????? ?????? ??? ????? ?

?????????? SAIB ?????? ?????????? ????????? ?????????????? ??? ???????????? ???????????????? ??????????????? ??? ?????? ???, ??? ???? ????? ??? ??? ???? ??????? ?????? ??????? ???? ????, ??????? ???????? BASF ?????? ????????? ??????? ?????? ???????? ????????? ???? ???, ?? ?????????? ????????? ???℃ ???? ??℃ ? ?????? ???, ?????????? ????????? ??? ??% ?????? ??? ??? ?????? ??????? ??% ?? ?????? ???? ????? ???????? ?????????? ?? ?????? ??????????? ?? ??????????? ?????????? ??? ??????, ??? ??????? ?????? ?????? ?,??? ? ???

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?2. ???????? ?????????? ?????? ??????? ?????? ?

???????????? ??? ?????????? ??????? ??? ???????? ????? ?????????? ??????? SAIB-?? ????????? ??? ???-??????????? ??? ????? ??? ???? ????????????:

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? ??? ???????? SAIB? : ??????? ?????? ????????? ?????? ???? SAIB-PEG ????????, ?????? ??? ????????, ???????????? ??????? ?????-????? ???????????? ????? ?????? ??????? ???;

? ????? ??????? SAIB? : 3M ??? 3D ????????? ??????? ??????? ???? ??????? ?????, ?? ??????? ???? 5 ???????? ???????? ??? ???????? ????? 20% ?????? ??????

? ???????, ????? ??????? ????????: ????-????? ??? ??????? ??????????? ?

??. ??????-???????? ?????????? ????? ?????????? ???? ??????????? ???? ????? ?

??? ? ?????? ??? ???????? ??????????? SAIB-?? ?????? ???????? ?????????? ???????, ???? ????, ????? SAIB ?????? ???? ??% ?????? ???????, ?? ???? ?????? (??%), ???? (??%) ??? ????? ????? (??%) ??????? ???? ???? ????? ???????????, ????? ?????? ????????? ????? SAIB-?? ????? ?????? ????????? ???? ????????? ??????? ??????? ??????????? ???, ??? ???????? ?????? ??????? ???????? ?? ??????? ?????????? ????

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?2. ???????? ???????? ?????????? ?????? ?????? ???? ???

???????? ????????? ????? ????????? ???? (SCS) ???? ????? ????? ??% ????????????-??????? ?????????????? ??????? ???? ?????? ?????????? ???-??????? ?????? ?????? SAIB, PVC ????? ??? ??????? ?????? ??? ???????? ??? ????????? ?????? ??? ?????? ??????? ???-??????? ??????? ???????????? SAIB ????? (???? ???? ???? ????? ?????? ???????? ??? ???????) SAIB-??????? ??????-?????? ????? ?????? ???? ????? ?? VOC ????????? ?.?ppm-?? ???? ?????? ?????

??. ????? ???????? ???????????? ??????? ????? ?????????? ???? ?

???? ????? ????? ???????, ?????? SAIB-????????? ????????? ??? ?????? ?,??? ???????? ????, ??? ????? ?????? ??? ?????????????? ??????? ??????? ???????????? ???????? (IFF) ??? ??????? ????? ??% ??? ??? ???? ????????, IFF ?????? ???????? CJ ??????? ???????? ??? "SAIB-????????????? ???????? ???????????? ?????????" ??????? ???? ????? ?????, ??? ??? ??????? ??????? ???? ???? ?????, ?? ??????? ???????? ??????? ????? ?????? ?????? ???????? ?????? ??????

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? ????????? ??? ????????: ?????????? ??? ????????? ????? ?

SAIB-?? ??????????? ????????, ??? ???? ???? ?????? ??????????? ????????:

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? ???????? ???????? ???? ? : ??????????? ????? ????? ??????? SAIB-?? ??? ????????????? ???????? ???, ???????, ?????????? ??? ???????? ?????? ?????????? ????????? ??????? ???? ??????? ?????????? ???? ?????????? ??????? ?????

? ???????????? ????????? ?????? ? : ???? FAO/WHO ?????? ????????? ADI ??? 0-10 ?????????/????, ???????????? ????? ????????? ????????? 2024 ???? SAIB ??????? ?????????? ????????? ???????? ????? ?????? ??????? ??? ?????????? ?????? ???? ???? ?

????????, ????????? ???????? ??? ???????????????? ???????? ???????, SAIB ????? ????????? ????? ??? ??????? ???? ??????? ??? ?????? ????????????? ?????? ????? ???? ??? ??? ??? ?????? ?????????????? ???????? ?? ??? ???????? ??????? ???????? (IFT) ???????????? ????? ?? SAIB ?????????? ????? 2030 ????? ????? 5 ??????? ???? ???????? ????, ?? ??? ????????? ???? ???????????? ?????? ???? ?????

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???????

?? ???? ?????????? ?????? ???? ???? ??? ?????-???????? ???-??????? ?????? ???, ?????? ?????? ???????? ???? ???? ??? ???? ????????? ?????, SAIB ??????????? ????? ????????? "???????? ???????????" ?????? ???????? ????? ??????????? ??????? ??? ?????? ???????? ??????? ???????? ?????, ????? ?????????? ?????? ????? ?? "???? ??????" ??????? ????? ????? ????????? ??????