?. ???????? ????????? ??? ????? ??????? ???????????? ??????

?. ????? ???????? ??? ???? ???????? ?????????? ???
???????????? ??????? ??????????? ????? ??? ???????? ???? ??, ??????? ?????????? ????? ????????? ???????? ????? ???? ??????? ??????????? ???? ?????? ?? ?????? 85% ??????? ??? ?????? ???????? ??????? ?????? ???, ??? ???? 15% ????? ?????? ?-??????? ????????? ??????? ??? ??? ????????? ?????? ??? ?13? ?? ??????????? ????? ???? ?????????? "????? ????????" ?????? ??? ????, ?????????? ??????? ???? 9 ?????????/???? ??????? ????? ???? ???? ???????? ?????? ???? ???? ?? ?28?

2. ?????? ??????? ??????????? ??????????
? ??????? ???????? ?: ??????????? ?????????? ???????? (IDF) ?? ???? ????? ???? ???????? ???? ???? ?? ????????? ???????????? ???? ???? ?????? ????? ????????? T1R2/T1R3 ??????? ??? ?? ??? ??????? ?????? ?57 ??????? ??? ???
? ??????? ???? ????? ?: ????????? ???????, ??????? ?????????????? SGLT1 ??????? ??????????? ????????????? ????????? ??? ?? ??? ???????? ??????? ???? ?????? ????????? ????? ????? ???? ?36? ????????????, ???? 2 ??????????? ???????? 50 ?? ??????? ???? ???? 30 ??? ??? ???????????? ?????? ??? ???????? ????? A1c (HbA1c) ?5 ?? ???????? 0.3% ??? ?? ??????? ???? ?????
?????????, ????? ???????????? ????????? ?????

?. ?????????? ???? ????????????? ??????????
??????????? ??????? ????????? ????? ??? ??? ????, ??? ??? ???? ???????? ??????? ?????? ???? ??? ?????? ????????????:

??? ???? ????-????? ???????? ?? ????????? ??????????? ??? ???? ??% ??????? ??????? ??????? ??????? ????? ??? ????? ???;
???? ????? ????? ??? ????? ?????? ???? ?? ????????? ??? ???? ????????? ?????? ?????? ?? ????? ??? ??? ?????

2. ????????????? ?????? ???????????? ??????
? ?????????????? ???????? ????? ?: ?????????? ?????????????? ??????????? ???, ?????????? ?????? ?????????? ?????????????? ????? ??-?? ????? ????? ?????, ?? ???-??? ??????????? ???????? ?????? ??????? ?27;
? ????? ????????????? ????????? ?: ???????? ??? ????? ??? ????-??????????? ??????? ?????? ????????? ?????? ??????? ??????? ?????????? ???????? ???????????? 40% ??? ???? ?????? ??????? ?38?
???????, ????????? ?????? ???????? ??????

?. ???????????? ?????? ???????? ????
? ?????? ??????? ????? ????? ?: ????? ???????????? ??????????? ???? ????? ???? ?? ??? ?? ????????-???????? ????????? ?????????? ??????? ????? ????? ????????? ??? ??% ?????? ???? ?46;
? ??????????? ??????? ? : ??????? ????????????? ??, ??????? ????????????????? ?????? ???? 0.4mmol/L ??? ???? ??? ?? ??????? ?????????????? (LDL) ????? 12% ??? ?????

2. ????? ??????????? ??????????????
? ???? ?????????? ??????????? ?: ??? ?????? ??????????? ???? ??? ???? ????, ????????? ???????????????? ??? ??????? ????? ???? ???? ??, ?? ?? ????????? ???????? ????? ???? ??????? ?38;
? ?????? ????????? ?: ???????? ??? ????????? ??? ?????????? ??????? ??????????????? ?????? ???? ???? ???????????? ???, ??? ?????????? ?27 ?? ??? ?????????????????????? ?????? ???? 2 ?????? ???????? ????? ??? ?????
???????, ?????? ??? ??????? ??????

?. ?????? ????? ???
??????? ?????? ????? ?????????? ??????? ?????? ??? ??% ????? ??????? ??? ???????? ????? (PHQ-9) ????? ?68-? ???? ?.? ??????? ????? ???????? ???? ????? ?????? ????? ???? ???? ?? ????? ?????? ?????? ????????? ????????? ?????????? ??????? ????? ????????????? ????????? ??% ???? ????? ??%-? ???????

2. ????????? ??? ????????????
? ??????? ????? ????? ?: ?????????? ??, ???????????? ??? ???????? ??????? ??????? ??????? ??? ?????? 3200 ??????/??????? ?78 ????? ????;
? ????? ??????? ??????? ?: ????-????? ????? ??????? ??????? ??% ???? ?????? ???? ???? ??????? ??? ??? ???? ???? ??? ??? ??????? ?????? ???-? ??????? ??? ??? ??? ??????

?. ??????? ???????????? ??? ????????? ????????

?. ????????? ????????? ????????
? ??? ?????????? ?: WHO-?? ?????????? ????? ?????? ????? ???????? ???? 9mg/kg (60kg ???????????????? ???? ?????? 540mg) ?28 ?????? ????;
? ?????????? ???????? ?: ???????? ???????? ??? ?????? ????? ???????????????????? ????????? ?????????? ?????????? ?????? ??????? (???????????????????? ??????????? ??????? ??? 30% ???? 8% ? ?????? ??? ???????) ?18?

2. ????????? ????????? ????????????
? ??????? ?????????? ????????? ? : ???? ???? ????? ??????????? ?????? ?????? "????????? ??????????" ?????????? ???????????????? ??????? ?????? ?.??ppm?? ? ?????? ???;
? ??????-??????? ??????? ?????? ? : ??????????? ?????????? ????????????? ????? ??????? ??? ??????????? ???????????? ?????? ??????????? ???? ?56-?? 100,000-???????? ??????? ?????? ???? ??????
???????
??????????? ?????????? ??????? ??? ???? ?????? ?????? ??? ?? ????????? ???????????? ???? ??????? ??????? ???????? ????? ????? ?? ??? ???????????? ???????? ?????, ????? ????????? ??????????? ??? ?????? ????????? ?????? ????? ?????? ?????????? (???? ???????????????????? ?????????) ??? ????? ?????????? ???????? (???? ???? ???? ????? ????-???????? ??????? ???? ?????? ??????? ?????????? ??????) ?? ???????, ??????????? ?????????? ????? ???????????? ???? ???? ?????? ??? ??? ??????? ???????? ???? ????? ???, ??? ??? ????? ??? ???? ?? ????? ?????? ???? ????? ??? ???????? ??????? ??? ??????? ??????????? ???? ???? ?? ??? ????????? ??????? ???????????? ??????? ?????????? ? ?? ??? ?????? ??? ????? ?????