????????????? ???????? ??????? ????????? ?????? ???????? ???? ??????? ???? ??????????? ??? ?????? ?????? ??. ???? ???? ? ?? ?? ????????????? ?????????? ??? ?????? ??? ??, ??? ????? ????????? ?????? ??? ???????????? ??. ???????????? ???????? ??????? ?????? ????? ?????????? ??? ?????? ??????? ???? ???? ??:

????? ???????? ??????? ??????: ????????????? ??? ??????
?????????? ??????????? ??????

????? ????: ???? ??????? ????? ?????????? ????? (??? ?? ????????? ???????, ???????? ??????????) ???? ??? (??? ?? ??????????????????? ??????????????).
???????? ?????? ????????????: ?????? ????????? ???????? ?????? ?????? ?????????? ??????????? ?????? ???????? ??????? ?? ??? ???? ???????? ???? ?????????? ????? ??.
???? ????? ?????????

?????? ???????: ??????? ???? ??????? ?????????? ????? ??? (30-35% ?????? ???????? ????, ?????????? ?????????? ?????????? ???? ???? ???? ???????? ??????? ????? ??).
?????? ??????: ?????? ??????? ???? ????? ???? ????? ??????????? ???????????? (α - ??????+??????) ?????? ?????????? ????????? ?????? ???? ??.
??? ???????? ?????????

??????? ????????? ???: ???? ??? ????????? ???? ?????????? ??? ?????, pH (5.0-6.0), ?????? (28-34 ℃) ??? ?????? ??????? ?????? ??? ???? ????????? ???.
???? ???????? ???? ??????: ???? ??????? ???????? ????, ???????????? ??? ???????? ?????? ??????? ???? ???? ?????? ????????? ????????????? ????????? ??? ??.
??? ???? ??? ????????? ?????? ????? ?????

???????? ??????? ?????
?????????? ???? ??? ???? ?????? ???????? ??? ???? ???? ????????? ??????????, ????????????????? ???? ????????????????
???????????? ?????????? ?????? ?????? ???????????? ???? ?? ??, ??? ?????? ????? ????????? ??????? ??? ??? ??
????????? ?????????? ?????????? ????????? ???????? ?? ?????????????? → ???? ?????????? (??? ????? ??? ???? ???? ????????? ?????)
????????????? ??????, ?????????? ????????????? ?????? → 99.5% ?? ??? ??????????? ???? ??????? ?????? ???? ?????????? ??? ??????
?????? ????? ??? ??????? ????? ????????? (???-????????)
???? ???????? ??????? ??? ?? ???? ???? ??, ?????????? ?????? ???? ???????? ????? ??:

???: ???????, ??????, ????? (???? 0.005-0.1%)
??? ????? ?????: ???? ???, ???
????????? ????????? ?????? (????? ????????? ?????? ????? ????):
????????
??? ???? ???
????? LR
A [????? ???????????] --> B [??? ???? ?????????]
B -->C [?????? ??????? ?????????????]
C -->D [??? ?????? ?????????????? ?????????]
D -->E [????????????? HPLC ??????]
????????: ?????? ??? ??? (???? ???? ???????? ??????? ???? ????????? ?????
?????????? ?????????? ????????/?????????
??? ????????? ???????/??????? ????????????? ????????????? (??????)
????????????? ????????: ?????????? ??????? ??? (25 ℃ ?? 37 ?????/100 ??????? ?????????). ????? ????? ???? ???? ??????????? ???? ???? ?????????? ?????? ???? ??.
?????? ?????: ???? ???? ?????? ????? ??? (??????????? ??????
?????? ?????: ???? ????? ??????? 30% ?? ??? ????? ???? ???? ???????? ????????? ??????????????? ??????????????? ??????? ??????.
??? ???: ???? ??? ??????????? ??? ??????? ??????? ??? ??, ??? ?????? 48 ???? ???? ??????? ?? ??.
???? ??????????: ???????????? ?????? ?????????? ????????? ?????? ??????? (>99.9%) ?????? ?? ??? ????? ????? ????? ??.
????????
????????????? "?????????" ????????? ???????? ??? ??? ?????? ??????????? ?????? ??? ??, ??? ?????? ???????????? ???? ?????????? ????? ??. ?????? ????????? ???????? ???? ??????????? ???????, ???? ???????? ??? ??? ?????? ????????? ???????? ????? ????? ?? ????? ???? ?? ??? ????? ??????? ??????? ??? ??, ?? ????? ???????? ??????? ?????? ????? ??? ??. ?? ?????? ????????? ??????? ???? ??????? ?????? ???????? ???? ???, ?? ??? ????????? ???? ???? ???? ???? ??.