HMB ? ???? ?????? ????? ???? ?????????? ????????? ?????????? ??, ??? ???? ???? ???? ? ???? ????????? HMB ??????? ??? ??? ??. ??????? ???????, ???? ???? ????? ???? 300 ?? 400 ????????? ??????? ??? ??, ??????? 90% ????????? ????????? ??? ??. HMB ?? ????? ????????? ???????? ?????????? ????, ???????????? ????? ??????, ??????????? ?????? ??? ??????? ??? ???????? ?????????????? ???? ?????? ???? ?? ??? ?? ???? ??????? ???? ??? ??? ?????????? ????? ???? ??? ???, ????? ?????? ????????? ???????? ?????? ??????, ??????? ?????????? ???? ?????? ??? ??????? ???? ?????????? ????????? ????????? ????? ????? ???? ?? ?? ??? ??. ???????? ????????, ???? ?? ?? ???? ??? ?????? ??????? ???????? ????? ??? ??, ?????? ???????? ??????? ??? ??? ??, ????????? ???????? ????? ??? ??? ?? ??? ?????? ???? ???? ??? ??, ?? ???????? ???? ??????????? ?? ????? ??? ??? ???? ??. ??????, HMB ???? ??????? ??? ???? ??? ??????? ????? ???? ????????? ????? ???? ??. ???????? ?????????? ?? ?? Ca HMB ??????? ?????????? ??? ??? ??? ?? ??? ??????? ????? ???? ??? ??? ??. ?????????? ??? ????????? ???? Ca HMB ??? ?????? ???????? ????????? ????????? ???????? ?????? ??? ?? ??? ??? ??? ????????????????? ??????????????? ????????? ?????? ???? ??? ??.

2011 ???, ????? ???????? ?????? ????????? β-???????????-β-???????????????? ???????? (Ca HMB) ?? ??? ?????? ????? ????? ?????? ?????? ??????? ???, ?????? ???? ??????? ?????, ??? ????? ????? ?????????? ?????, ????? ???? ??? ≤3 ?????/???? ??. 2017 ???, ????????? ?????? ??? ?????? ????? ???? Ca HMB ?? ??????? ????? ??? ?? ???????????? ?? ???? ???????? ??????? ???, ??? ?????? ????????? ???? ???? ???? ????????? ????????? ????????? ?????. Ca HMB ?? ????? ?????, ??? ??? ???? ????????, ???? ????????, ?????? ??? ?????? ????????, ??????, ???? ????? ??? ??? ???? ??????? ?????? ???? ???? ??????? ??????? ?????, ??? ????? ???? ??? ??? ?? ≤3 ?????/???? ???, ?? ???? ??????? ???????????? ??? ????? ??? ? ???. Ca HMB ?? 1995 ??? ???? ??? ???? ???? ?????????????? ?????? GRAS ????? ??????? ??????? ??? ??? ??? ???? ????? ????? ???? ????? ??? ??? ??????? ??? ??. ?????? 20 ????????, Ca HMB ?? ????? ???? ??????? ???? ????????, ?????? ????????, ?????, ????? ??? ??? ???? ???????? ????????? ??????? ????? ??. Ca HMB ? ?????? ????? ?????? ????? ????? ???? ??? ??, ?? ??????? ?????, ?????? ???? ?????, ??? ???????? ?????, ??????? ????? ????? ???? ??? ??????????? ????? ???? ??. ???? ????? ???????????, ?????, ????? ????? ???? ???? ?????????? ?????????? ??? ????? ?? ?? ??? ??. ???????? ??? ???????? ????, Ca HMB ?????? ?????? ??????? ???? ???????? ?????? ?????????? ?? ??.