?????????? ???? ????? (ALD), ?? ????? ??? ???? ???? ???? ?????? ??? ???? ??? ??, ?? ?????? ??????? ???? ????????? ?? ??, ????? ?????????? ???? ????, ?????????? ??????????, ?????????? ???? ?????????? ??? ?????????? ????????? ?????? ??? ??. ???????? ????????, ?????? ?????????? ???? ??????? ????? ???? ??? ??.

2 ?????, 2024 ?? ???, ?????? ????????????? ???? ?????, ????? ?????? ????????????? ???? ???, ????? ??????????? ?? ?????? ???? ??????????? ??? ?? ??? ???? ???????? ??? ????? ???? ???????? "???????????? ????????????? ??? ??????? ??????? ??????????????" ???????? "??????? ????? ????????? ?????????? ???? ?????? ???" ?????? ???? ?? ??? ???????? ?????.

???????? ??????? ???? ??????? ????? ????? B. accidifaciens ?? ?????????? ????? ??? ?? ??? ????????-??????? ?????? ?????? ????? ??.

?????? ??, B.accifaciens ????? ???? ???????????? ??????? (BSH) ?????? ????? ???? ????????? ????? ??? ??. ??????????? ????? ??????? ?????? ?????? ????????? FXR-FGF15 ????? ?????? ??? ??, ???????? ????? ???????? ????? ??? ??, ??????????????? ???????? ????????????????? (OAT) ?? ???????????? ?????????? ??? ??, ??? ?? ??????? ????? ??????????? ???????????? ?????? ?????????? ??? ??. ?????? ?????????????? ???? ???? ??? ???? ???? ?? ??? ?????? ?????? ?????? ????? ??.

? ?????????, ???????? ??????? ???? ???????? ?????????? ???? ??? ??????? ????? ??? ??????? ??? ???????? ???? ??????? ???? ??????? ???????? ?????????? ???? ??? ?? ??????? ??????? ??????? ???????? ??????.

?????????? ????? ?????? ?? ??????? ???? ????? ???? ???????? ?????????? ???? ?????? ????????? ?????? ??? ??, ????? ???? ????????? ?????? ??? ???? ??????????????? ??????? ??? ??? ????????? ????? ????? ??, ?????? ???????? ???? ??????? ????????? ??? ?? ???.

??????? ????? ???????? ??????????????? ????????? ???? ??? ??? ??? ??, ???? ???????? ??? ???????? ?????? ?? ??? ?????????? ???? ?????? ?????? ????????????? ????????????????? ?????? ?????? ???????? ??????????????? ????? ??.

????????????????? ???, ???? ????? ?????? ?? ??????? ??????? ???? ????? ?????????? ???? ???????????????? ????????????????? ?????? ???? ??????? ????????????????? (ALT) ??? ?????????? ????????????????? (AST) ???? ??????, ?????? ???? ????????? ??? ????? ???? ??????, ?? ????? ?? ?? ??????? ???? ????? ???????? ??????????????? ?????? ????? ???? ????? ALD ?? ??????? ???????? ??? ??? ??.

????????? ??????????? ?????? ?? ?? ??????? ???? ???? ?????????? ???? ????? ???? ???????? ???? ??? ?????????, ???? ????????? ??? ???????? ?????? ??? ??, ??? ??????? ??????? ???? ??? ?????????? ???? ?? ????? ??, ?? ?????????? ???? ????? ?????? ??? ????????? ??????? ???? ?????? ?????????? ??? ??????? ??.

? ??????? ???????? ?? ?? ????? ???? ?????? ??????? ???? ????? 25-30 ????? ?? ???? ??? ??????? ????? ?????? ????? ??????? ??? ??, ????? ????????? ???? ??????? ???????? ????? ???? ???. ??? ????, ??? ??? ??????? ??????? ??????? ?????? ??????? ?? ??? ???? ?????? ??????? ??????????? ???? ???? ??? ??.

?????????, ??????? ????? ?? ?? ??????? ???? ??????? ????? ???? ???? ????????? ????????-??????? ?????? ????? ?????? ??? ?? ?????? ???????? ??????? ?????????? ???????? ??? ??? ??. ? ????????? ?????? ???????? ????? ??? ??????? ????? ??.

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