HMB shine matsakaicin metabolite na mahimman amino acid leucine na ?an adam, kuma jikin ?an adam yana iya samar da ?aramin adadin HMB da kansa. A cikin abinci na yau da kullun, jikin mutum yana samar da kusan 300 zuwa 400 MG kowace rana, wanda kashi 90% ya fito ne daga catabolism na leucine. Ana iya amfani da HMB don ha?aka ha?akar tsoka, ha?aka garkuwar jiki, rage ?wayar cholesterol da ?arancin ?arancin lipoprotein a cikin jiki don rage faruwar cututtukan zuciya da cututtukan zuciya, amma kuma don ha?aka ikon daidaita sinadarin nitrogen na jiki, kiyaye matakan furotin a cikin jiki, da hana ru?ar tsoka a cikin marasa lafiya marasa lafiya ko shanyayye. A cikin 'yan shekarun nan, saboda yana iya rage lalacewar ?wayar tsoka bayan motsa jiki, gyara ?wayar tsoka, ?ara ?arfin tsoka da ?ona kitsen jiki, ya zama wani sinadari na tauraro a cikin kayan abinci na wasanni. Bugu da ?ari, an tabbatar da HMB a asibiti don hanzarta warkar da raunuka da kuma hana kumburi. Nazarin ya nuna cewa Ca HMB na iya hanzarta ha?in furotin da rage yawan amfani da furotin. Ca HMB tare da glutamine da arginine na iya inganta ma'auni mara kyau na nitrogen na marasa lafiya kuma suna taka rawa mai kyau a farfadowa daga rauni da tiyata.

A cikin 2011, tsohuwar ma'aikatar kiwon lafiya ta kasar Sin ta sanar da amincewa da β-hydroxy-β-methylbutyrate calcium (Ca HMB) a matsayin sabon kayan abinci na albarkatu, amfani da abinci mai gina jiki na wasanni, abinci na musamman na amfani da likitanci, adadin shawarar shine ≤3 grams / rana. A cikin 2017, Hukumar Lafiya da Tsarin Iyali ta ?asa ta ba da sanarwar fadada iyakokin aikace-aikacen Ca HMB daga aikace-aikacen asali guda biyu zuwa tara, kuma ta ba da izini cibiyoyin fasahar tantance ha?ari don gudanar da tantance aminci. An fa?a?a amfani da Ca HMB zuwa abubuwan sha, madara da kayan kiwo, samfuran koko, cakulan da samfuran cakulan, alewa, kayan gasa, da abinci na musamman na abinci, kuma adadin shawarar har yanzu ≤3 g / rana, wanda bai wuce adadin masu sa kai na gwaji na ?an adam ba. Cibiyar Abinci da Magunguna ta Amurka ta amince da Ca HMB a matsayin GRAS a cikin 1995 kuma ana amfani da ita a abinci mai gina jiki na likitanci da abinci na musamman. A cikin shekaru 20 da suka gabata, Ca HMB an yi amfani dashi sosai a cikin samfuran kiwo, samfuran cakulan, abubuwan sha, mashaya makamashi da sauran abinci a kasuwannin Amurka. Ca HMB wani kayan abinci ne da ka'idojin Jafananci suka ba da izini, wanda za'a iya ?arawa a fannoni da yawa kamar abinci na yau da kullun, abinci mai gina jiki na wasanni, abincin asarar nauyi, abinci mai kyau, da sauransu Hakanan ana iya amfani dashi azaman kayan aiki mai aiki a cikin abubuwan abinci na abinci kamar capsules, allunan, abubuwan sha masu ?arfi. Ga masana'antun da kantin magani, Ca HMB a halin yanzu yana ?aya daga cikin shahararrun kayan aikin lafiya a kasuwar Japan.