Lycopene (LYC), carotenoid, wani launi ne mai narkewa, wanda akasari ana samun shi a cikin tumatir, kankana, innabi da sauran 'ya'yan itatuwa, shine babban launi a cikin tumatur. Lycopene yana da fa'idodin kiwon lafiya iri-iri, gami da ?ata radicals kyauta, sau?a?e kumburi, daidaita glucose da metabolism na lipid, da tasirin neuroprotective.

Kwanan nan, Masu bincike daga Jami'ar Kiwon Lafiya ta Shanxi sun buga wata takarda a cikin mujallar Redox Biology mai suna "Lycopene yana rage ?arancin fahimtar shekaru ta hanyar kunna hanta-kwakwalwa. Takardar bincike na fibroblast girma factor-21 sigina ".

Nazarin ya nuna cewa ?arawa tare da lycopene na watanni 3 na iya jinkirta tsufa na kwakwalwa a cikin mice da kuma rage lalacewar ilimin da ke da alaka da shekaru, kuma lycopene yana inganta lalacewar neuronal, dysfunction mitochondrial, lalacewar synaptic, da kuma inganta ha?in gwiwar synaptic vesicle a cikin tsofaffin mice.

Bugu da kari, lycopene kunna hanta-kwakwalwa axis FGF21 sigina a cikin tsofaffin mice, don haka inganta sakin neurotransmitters ta ?ara mitochondrial ATP matakan da kuma inganta synaptic vesicular fusion. Wannan yana nuna cewa FGF21 na iya zama ma?asudin warkewa a cikin dabarun sa baki na abinci mai gina jiki don jinkirta tsufar ?wa?walwa da ha?aka rashin fahimta da ke da ala?a da shekaru.

A cikin tsufa, tsufa na kwakwalwa, rashin aiki na mitochondrial yana daya daga cikin muhimman abubuwan, masu bincike sun gano cewa lycopene supplementation na iya inganta lalacewar ?wayoyin cuta na mitochondrial, da kuma sake mayar da matakin hadaddun jigilar jigilar lantarki na mitochondrial wanda ke haifar da tsufa, inganta samar da ATP, yana nuna cewa lycopene yana da tasiri mai kariya akan aikin mitochondrial.

A ?arshe, masu binciken sun kuma gudanar da gwaje-gwaje a cikin vitro kuma sun gano cewa lycopene yana ha?aka ikon ?wayoyin hanta don tallafawa neurons, ciki har da inganta tsufa na cell, inganta aikin mitochondrial, da kuma ?ara tsawon axon neuron.

A hade tare, sakamakon ya nuna cewa karin lycopene na iya jinkirta tsufa na kwakwalwa da kuma hana rashin lafiyar da ke da alaka da shekaru a cikin mice, a wani ?angare saboda lycopene yana kunna hepato-brain axis FGF21 sigina, yana nuna cewa FGF21 na iya zama ma?asudin warkewa a cikin tsoma baki don inganta fahimi da cututtukan da ke da ala?a da ha?akar ha?akar ?wayoyin cuta.