Youdaoplaceholder0 1.1 Sihiri na zahiri na danko gradient: Sauyi sau uku daga ciki zuwa hanji

Tsarin kwayoyin halitta na polyglucose ya ?unshi ragowar glucose masu ala?a da bazuwar, kuma wannan ?ayyadaddun ?ayyadaddun ?ayyadaddun ?ayyadaddun ?ayyadaddun ?ayyadaddun ?ayyadaddun ?ayyadaddun rheological ya ba shi. A cikin yanayi mai yawan acidic na ciki (pH 1.5-3.5), sar?o?i na ?wayoyin cuta suna sauri suna samar da tsarin cibiyar sadarwa mai girma uku ta hanyar ha?in hydrogen, kuma danko nan take yana ?aruwa zuwa 1200 mPa·s (kimanin sau biyu na zuma), yadda ya kamata yana jinkirta yawan zubar da ciki har zuwa 40% kuma yana tsawaita jin da?in jin da?i. Bayan shigar da ?ananan hanji, yayin da ?imar pH ta tashi zuwa 6.0-7.5, wasu ha?in gwiwar hydrogen suna karya kuma danko ya ragu zuwa 300-500 mPa·s. Baya wuce gona da iri yana hana sha na gina jiki ko ha?uwa da bile acid don rage yawan sha na cholesterol. Lokacin isa ga hanji, ?ar?ashin aikin ?wayar ?wayar cuta, danko yana ?ara raguwa zuwa ?asa da 50 mPa·s, yana sakin gajeriyar sarkar fatty acid (SCFAs) don samar da makamashi ga probiotics (Hoto 1).

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Tallafin bayanan Youdaoplaceholder0:

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Adadin jinkirin zubar da ciki: 40% (Abinci Hydrocolloids 2022, n=30)

Adadin hana ?wayar cholesterol: 22% (bayanan takaddun shaida na GRAS daga FDA ta Amurka)

Ha?aka samar da SCFAs: Tsarin acetic acid na Colonic ya ?aru sau 3.8 (Gut 2023, Model Dabbobi)

Youdaoplaceholder0 1.2 "Madaidaicin ciyarwa" dabarun microbiome ?

Tsarin danko na polydextrose ba wai kawai yana rinjayar tsarin narkewar jiki ba, har ma yana haifar da hul?a mai ?arfi tare da flora na hanji. Babban yanayin danko yana haifar da shinge na jiki a cikin hanji na kusa, yana rage hul?ar tsakanin ?wayoyin cuta da ?wayoyin hanji. Yayin da danko ya ragu, sannu a hankali yana rikidewa zuwa wani abu mai ?ishirwa, wanda zai fi dacewa yana ?arfafa yaduwar Bifidobacteria da kwayoyin lactic acid. Tawaga daga Jami'ar Cambridge ta gano ta hanyar tsarin metagenomic cewa ci gaba da cin abinci na 12g/rana na polydextrose na tsawon makonni 8 zai iya ha?aka ?imar F/B na Thick-miliae/Bacteroidites zuwa 1.3 (tare da ingantaccen tushe na 1.5-2.0), kuma yana ?ara yawan ?wayoyin butyric acid (kamar Face 8%). Wannan tasirin matakai biyu na "kare farko, sannan abinci mai gina jiki" daidai ya dace da bukatun muhalli na sassa daban-daban na hanji.

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Youdaoplaceholder0 Babi na 2 Aikace-aikacen Juyin Juyin Halittu: Tsallake kan iyaka daga Abincin da ke sarrafa Sugar zuwa Gina Jiki na ICU

Youdaoplaceholder0 2.1 Masana'antar Abinci: "kwarangwal marar ganuwa" na ?ananan samfuran GI

A fagen yin burodi, babban ?arfin ri?e ruwa (> 8g ruwa / g) da kwanciyar hankali na thermal (ha?uri zuwa 200 ℃) na polyglucose ya sa ya zama madaidaicin madadin sucrose. "Kukis ?in Sifiri" da ?ungiyar Meiji ta Japan ta ?addamar suna amfani da polyglucose a matsayin babban fiber, wanda ke samun kawai 1.2g na carbohydrates mai sauri a kowane kuki, kuma laushi da ?ima ba su bambanta da na samfuran da ke ?auke da sukari ba. Mafi mahimmanci, ?a'idodin dankowar sa a cikin ?ananan hanji na iya jinkirta sha glucose kuma yana rage kololuwar glucose na jini da kashi 34% (bayanan asibiti daga Kula da Ciwon sukari 2021).

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Youdaoplaceholder0 Innovative case :

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Youdaoplaceholder0 Nestle : The "Smart jinkirin-saki makamashi mashaya" ?ullo da ta hanyar gauraye polydextrose tare da resistant dextrin siffofi da danko gradient zane cewa kara shan carbohydrate zuwa 6 hours, saduwa da ci gaba da samar da makamashi bukatun na gudun marathon.

Youdaoplaceholder0 Nongfu Spring ? : An ?addamar da "Ruwa mai kyalli na hanji" tare da ?arin polyglucose, wanda ke amfani da ?ayyadaddun kayan hadi mai ?arancin danko don samar da iskar gas mai laushi a cikin hanji don tada peristalsis na hanji. Ya sayar da fiye da kwalabe miliyan 100 a cikin watanni uku.

Youdaoplaceholder0 2.2 Likitan abinci mai gina jiki: "Mai tsaro na hanji" ga marasa lafiya na ICU

Rashin shinge na mucosal na hanji a cikin marasa lafiya marasa lafiya yakan haifar da cututtuka na tsarin. Gwajin gwajin da aka bazu (n = 158) wanda Asibitin Ha?in gwiwa na Farko na Jami'ar Zhejiang ya gudanar ya nuna cewa marasa lafiya na ICU wa?anda aka ?ara su da 15g na polyglucose yau da kullun sun sami raguwar 42% a cikin abin da ya faru na endotoxemia da raguwar 29% a cikin ma'aunin permeability na hanji (plasma ligonin). Hanyar ta ta'allaka ne a cikin cewa yanayin da ke da ?arfi yana samar da fim mai kariya a cikin ciki, yana rage ha?arin cututtukan da ke haifar da damuwa. Acid butyric da sashin mulkin mallaka ya fito da shi kai tsaye yana ha?aka kauri na lebe (?ara adadin ?wan?olin sel da kashi 37%), yana samun ?arfafa shingen biyu na zahiri da sinadarai.

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Mai ri?e da wurin0 Babi na 3 ?ir?irar Fasaha: Ha?akawa daga 'Tsarin ?a'idar' zuwa' Gina Jiki na Lissafi' ?

Youdaoplaceholder0 3.1 Madaidaicin ?a'ida na gyaran kwayoyin halitta

Matsakaicin martani na danko na polydextrose na gargajiya yana da iyaka, yana mai da wahala a daidaita daidaitattun bu?atun mutum. A cikin watan Yuni 2023, DSM na Netherlands ya ba da sanarwar fasahar sa mai suna "PolySmart ?", wacce ta ha?aka bambance-bambancen lan?wasa guda uku ta hanyar sarrafa matakin polymerization (?imar DP) na glucose da sorbitol:

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Youdaoplaceholder0 G nau'in ? (ha?aka ciki): Danko har zuwa 1500 mPa·s a pH

Youdaoplaceholder0 C nau'in ? (wanda aka yi niyya): Danko yana fa?uwa sosai zuwa 30mPa·s a pH> 6.5, wanda aka fi so ga mutanen da ke da ma?ar?ashiya;

Youdaoplaceholder0 Nau'in B (daidaitacce yanayin): Sauye-sauye mai sau?i na jimlar ?ankowar hanji, dace da sarrafa glucose na jini a cikin masu ciwon sukari.

Youdaoplaceholder0 3.2 AI-Taimakawa ?irar ?ira

Dandalin "FiberEngine" wanda kamfanin Isra'ila NutriAI ya ha?aka ya ha?u da bayanan microbiota miliyan 2 da samfuran kuzarin ruwa, wanda zai iya hasashen mafi kyawun adadin polydextrose a ?ar?ashin shekaru daban-daban da yanayin cuta. Misali, ga marasa lafiya da IBS (Irritable Bowel Syndrome), tsarin yana ba da shawarar ha?akar yau da kullun na 8-10g na polyglucose da 2g na fructooligosaccharides, wanda ke rage ha?arin kumburin ciki da kashi 65% (bayanin mai amfani na 2023).

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Mai ri?e da wuri0 Babi na 4 Rikicin Masana'antu: "Tsarin Fiber Blue" da Kattai ke fafatawa don

Youdaoplaceholder0 4.1 ?arfin tseren ya yi zafi

Girman kasuwar polydextrose na duniya ana tsammanin yayi girma daga dalar Amurka miliyan 870 a cikin 2023 zuwa dala biliyan 2.1 a cikin 2030 (CAGR 12.3%). Kasar Sin ta zama babban filin yaki.

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Mai ri?e da wurin zama0 Baolingbao Bio : Zuba jarin Yuan miliyan 500 don fa?a?a layin samar da tan 30,000 a kowace shekara, ta hanyar amfani da tsarin ha?akarwar enzymatic don cimma tsafta kashi 99.5%;

Youdaoplaceholder0 Rogate : Probiotic-polyglucose microcapsules ha?aka tare da ha?in gwiwar CHR. Hansen ya ?aru yawan tsira mai jure acid zuwa 90%;

Youdaoplaceholder0 Matsuya Chemie, Japan : An ?addamar da "nano-fibrotic polyglucose," wanda ke da ikon daidaita ?a'idar danko sau uku kuma FDA ta ba da izinin maganin marayu don gajeriyar ciwon hanji.

Youdaoplaceholder0 4.2 Kalubale biyu na tsari da fahimta

Kodayake an amince da polydextrose azaman fiber na abinci ta Tarayyar Turai, China da sauran ?asashe, masu amfani har yanzu suna da rashin fahimta. Wani bincike da FMCG ya yi a Amurka ya nuna cewa kashi 28% na masu amfani ne kawai ke iya bambanta bambance-bambancen aiki tsakanin polydextrose da sitaci mai juriya daidai gwargwado. Mafi mahimmanci, yawan cin abinci (> 50g / rana) na iya haifar da kumburin ciki ko tsoma baki tare da sha mai ma'adinai. Masana'antu na bu?atar gaggawa don kafa daidaitattun jagororin sashi.

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Mai ri?e wurin zama0 Babi na 5 Neman gaba: "Fiber Network" daga GUT zuwa Lafiyar Jiki ?

Youdaoplaceholder0 5.1 Sabbin shaida don tsara tsarin axis-gut ?

A farkon 2024, Cibiyar Fasaha ta California ta gano a cikin gwaje-gwajen linzamin kwamfuta cewa butyric acid da aka samar ta hanyar fermentation na polydextrose zai iya motsa ?wayoyin hypothalamic neurons ta jijiyar vagus, yana rage halayen damuwa da 43%. Wannan yana ba da bayanin matakin ?wayoyin ?wayoyin cuta don da'awar cewa "abinci mai yawan fiber yana inganta lafiyar kwakwalwa".

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Youdaoplaceholder0 5.2 ?ir?irar ?ir?irar ?ir?irar Halittar Halittu

Farawa na Amurka Zymergen ya yi amfani da fasahar CRISPR don canza Trichia pastoris, yana ba ta damar ?oye "polyglucose da aka gyara" kai tsaye tare da ke?antaccen danko. Wannan samfurin ya nuna ha?akar kashi 80% a cikin daidaiton amsa pH a cikin gwaje-gwajen narkewar narkewa kuma ana sa ran shiga matakin gwaji na asibiti a cikin 2025.

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Youdaoplaceholder0 Kammalawa: Sake fasalta " iyakoki masu hankali" na Fiber ?

Tasirin gradient danko na polydextrose yana nuna sabon zamani don fiber na abinci, yana motsawa daga "kariyar kari" zuwa "tsari mai aiki". Lokacin da bangaren fiber zai iya daidaita aikinsa da kansa don mayar da martani ga yanayin yanayin narkewa, muna iya ganin canjin yanayi a kimiyyar abinci mai gina jiki - ayyukan kiwon lafiya na gaba ba za su zama ?o?arin ka?aici na kwaya ?aya ba, sai dai rawar ha?in gwiwa na kayan wayo, microbiome, da hankali na wucin gadi. A matsayin wanda ya lashe kyautar Nobel a Chemistry, Frances Arnold, ya ta?a cewa, "Tsarin kwayoyin halitta sun riga sun sami damar da ba su da iyaka. Abin da muke bukata mu yi shi ne koyon sauraron 'harshen lokaci da sararin samaniya'."