1. Amfanin halaye na rayuwa da sarrafa glucose na jini

1. Sifili da adadin kuzari kuma babu sauran ragowar rayuwa
Bayan tsarin kwayoyin halitta na sucralose ya canza ta hanyar chlorination, tsarin narkewar jikin mutum ba zai iya bazuwa cikin sukari masu sha ba. Bayanan asibiti sun nuna cewa kusan kashi 85% ana fitar da su kai tsaye ta hanji bayan an sha, sauran kashi 15% kuma hanta ta shiga cikin abubuwan da ba su da guba kuma ana fitar da su a cikin fitsari 13. Wannan kadarar ta sa ta zama abin za?i na "sifili" na gaskiya, ba tare da ?arin nauyin kuzari ga masu ciwon sukari ba a adadin yau da kullun har zuwa 9mg/kg nauyin jiki 28.

2. Tsarin kwanciyar hankali na glucose na jini
Babu kuzarin insulin: Nazarin 2024 ta ?ungiyar Ciwon sukari ta Duniya (IDF) ta nuna cewa sucralose bai kunna mai kar?ar dandano mai da?i T1R2 / T1R3 a cikin ?wayoyin beta na pancreatic ba kuma bai haifar da ?oyewar insulin ba.
Ka guji sha glucose: Ba kamar sucrose ba, sucralose baya tsoma baki tare da aikin jigilar glucose na SGLT1 a cikin ?ananan hanji, kuma ana kiyaye ingancin glucose na hanji a matakin al'ada ?36. Misali, mutane 50 da ke da nau'in ciwon sukari na 2 wa?anda suka cinye abubuwan sha masu ?auke da sucralose na tsawon kwanaki 30 a jere suna da ?asa da 0.3% sauyi a cikin matakan A1c (HbA1c) 5.
Na biyu, da m darajar sarrafa abinci

1. Yiwuwar maye gurbin sukari na gargajiya
Za?i na sucralose shine sau 600 na sucrose, kuma ka?an ka?an ne kawai zai iya biyan bukatun ?an?ano. Misali:

?ara 30mg sucralose zuwa 300ml abin sha ba tare da sukari ba zai iya cimma za?i daidai da 10% sucrose bayani 16;
?ara 15mg na kowane 100g na gari a cikin kayan da aka gasa yana rage cin sucrose da kusan 45g 48.

2. Tasirin inganta tsarin abinci
Rage dogara ga carbohydrate : Ta hanyar maye gurbin carbohydrates na gargajiya, masu ciwon sukari na iya rage yawan abincin yau da kullun na carbohydrates da 50-80g, daidai da yankan adadin kuzari 200-320kcal?27;
Ingantattun nau'ikan nau'ikan abinci: Kar?ar yarda da abincin ciwon sukari sama da 40% ta hanyar ba da izinin amfani da abinci mai da?i kamar ice cream da kek 38.
Na uku, nisantar tasirin ha?arin lafiya

1. Hana matsalolin ciwon sukari
Yana rage ha?arin caries na hakori: ?wayoyin cuta na baka ba za su iya rushe sucralose ba, kuma kayan aikin anti-caries sun rage yawan kamuwa da baki da kashi 27% a cikin masu ciwon sukari 46;
Kare tsarin cututtukan zuciya: Bayan maye gurbin sucrose, matakan triglyceride na marasa lafiya sun ragu da matsakaicin 0.4mmol/L da ?arancin ?arancin lipoprotein (LDL) ya ragu da 12%?78.

2. Daidaituwa zuwa yanayi na musamman
high zafin jiki kwanciyar hankali: lokacin yin burodi a kasa 120 ℃, sucralose ba zai samar da guba ta-kayayyakin kamar chloropropanol, wanda ya dace da yin low-sukari irin kek ?38;
Daidaitawar ?wayoyi: ba shi da hul?a da magungunan hypoglycemic da aka saba amfani da su kamar metformin da insulin, amma yakamata a sha tare da magungunan kashe jijiyoyi kamar warfarin ?27 a cikin tazarar awa 2.
Na hudu, fa'idojin tunani da zamantakewa

1. Inganta ingancin rayuwa
Marasa lafiya masu ciwon sukari sun sami raguwar 62% a cikin damuwa na tunani saboda rashi mai da?i da matsakaicin raguwar maki 3.2 a cikin Sikelin Bacin rai (PHQ-9) maki 68. Binciken masu amfani da 2024 ya nuna cewa gamsuwar abinci tsakanin masu ciwon sukari wa?anda suka yi amfani da sucralose azaman madadin sukari ya karu daga 43% zuwa 79%?3.

2. Inganta farashin tattalin arziki
Rage kashe kudade na likita: zai iya rage farashin jiyya na shekara-shekara na ?afar masu ciwon sukari, ciwon ido da sauran rikice-rikice na kusan yuan 3200 / mutum 78;
?ir?irar masana'antar abinci: Ha?aka kasuwar abinci mara sukari don ha?aka da kashi 18% a kowace shekara kuma ana sa ran ya kai yuan biliyan 120 14 a shekarar 2025.

5. ?ayyadaddun aikace-aikacen da kuma makomar gaba

1. Ka'idodin amfani da kimiyya
Kula da kashi : Bi umarnin WHO da aka ba da shawarar babba na 9mg/kg na nauyin jiki na yau da kullun (kimanin 540mg ga manya 60kg) ?28;
Za?in tsari: an fi son samfuran fasahar microencapsulation don rage tasirin flora na hanji (an rage raguwar ayyukan bifidobacterium daga 30% zuwa 8%) 18.

2. Hanyar ci gaban fasaha
Fasahar sarrafa madaidaici: Tsarin "chlorination da aka ba da umarni" wanda masana'antar Jinhe ta ha?aka a cikin 2025 yana rage ragowar adadin chloropropanol zuwa 0.01ppm?8;
Binciken likita na tushen shaida: ?ungiyar Ciwon sukari ta Duniya ta ?addamar da nazarin ?ungiyar mutane 100,000 don tantance tasirin sucralose na dogon lokaci akan aikin islet 56.
?arshe
Sucralose yana ba wa marasa lafiya ciwon sukari maganin da ke daidaita bukatun dandano tare da kula da lafiya. Mahimman ?imar sa suna kunshe a cikin inertia na rayuwa, kwanciyar hankali na glucose na jini da rigakafin rikitarwa. Tare da ingantattun hanyoyin samarwa (kamar fasahar microencapsulation) da ingantattun tsarin ka'idoji (kamar bitar ka'idodin Lakabin Gina Jiki na kasar Sin don Kunshin Abinci a cikin 2025), sucralose zai zama kayan aiki mafi aminci kuma mafi inganci don sarrafa abinci na ciwon sukari. Duk da haka, ya kamata a jaddada cewa maye gurbin sukari ba zai iya maye gurbin ainihin matsayin daidaitaccen abinci da aikin motsa jiki ba, kuma amfani da kimiyya ya kamata ya dogara ne akan jagorar likita na mutum.