Shayi na daya daga cikin shahararrun abubuwan sha a duniya, musamman a kasar Sin. Shayi a kasar Sin ba abin sha ne kawai ba, har ma alama ce ta salon rayuwa da al'adu.

Ana ?aukar shan shayi a matsayin al'adar rayuwa mai kyau saboda shayi yana ?auke da nau'ikan mahadi masu fa'ida, irin su catechins, polyphenols na shayi da maganin kafeyin. Yawancin bincike sun nuna cewa ruwan shayi na iya hana ciwon daji, tsawaita rayuwa, rage ha?arin hawan jini, ciwon sukari, cututtukan zuciya da sauransu.

Cutar hanta mai kitse ba ta barasa ba (NAFLD) ita ce nau'in ciwon hanta da aka fi sani da ita a kasar Sin, tare da sama da marasa lafiya miliyan 150. A halin yanzu, babu wasu magungunan da aka amince da su don magance cututtukan hanta mai ?iba, kuma marasa lafiya na iya shiga tsakani kawai tare da canje-canjen abinci da motsa jiki. Sabili da haka, akwai bu?atar gaggawa don ha?aka sabbin dabarun jiyya.

Kwanan nan, masu bincike daga Jami'ar Kiwon Lafiya ta kasar Sin sun buga wata takarda mai suna "Epigallocatechin gallate yana rage cututtukan hanta maras-giya" a cikin mujallar Clinical Nutrition ta hanyar hana magana da ayyukan Dipeptide kinase 4 ".

Wannan binciken ya tabbatar ta hanyar gwaje-gwajen da aka bazu na asibiti, gwaje-gwajen dabba da gwaje-gwajen in vitro cewa EGCG, babban sinadarin bioactive a cikin koren shayi, yana taimakawa wajen inganta hanta mai kitse, ECGC yana hana tarawar lipid, yana hana kumburi, yana daidaita metabolism na lipid, yana hana lalacewar hanta, kuma yana inganta hanta maras-giya ta hanyar hana hanta mai kitse da diPP4.

Dipeptide kinase 4 (DPP4), wani protease wanda ke raba nau'i-nau'i masu yawa a kan tantanin halitta, yana tattara shaida cewa DPP4 yana taka rawa wajen ci gaban NAFLD, tare da marasa lafiya na NAFLD suna nuna aikin DPP4 na plasma mafi girma idan aka kwatanta da mutane masu lafiya.

A cikin wannan binciken, masu binciken sunyi nazarin yiwuwar tasirin EGCG a cikin marasa lafiya tare da NAFLD ta hanyar gwaje-gwajen da aka bazu na asibiti, sun lura da ha?akar EGCG akan hanta na mice samfurin ta hanyar gwaje-gwajen samfurin dabba, kuma sunyi nazarin tsarin inganta EGCG a cikin NAFLD ta hanyar gwaje-gwajen in vitro.

A cikin gwajin gwaji na asibiti wanda bazuwar da ke tattare da mahalarta 15 tare da NAFLD, EGCG an cinye shi ta allunan polyphenol shayi, kuma an auna bayanan hanta a asali, makonni 12, da makonni 24.

Sakamakon ya gano cewa marasa lafiya sun sami raguwar ?wayar hanta sosai bayan makonni 24 na maganin EGCG idan aka kwatanta da asali, kuma biyu daga cikin marasa lafiya sun sami gafarar hanta mai kitse bayan ?arshen lokacin jiyya na 24 mako. Bugu da kari, kewayen kugu na marasa lafiya da jimillar matakan cholesterol shima ya ragu sosai bayan makonni 24.

Binciken ya nuna cewa bayan makonni 24 na maganin EGCG, an rage matakan AST kuma an rage matakan DPP4.

Binciken ayyukan koda ya nuna cewa matakan creatinine na jini da ?imar tacewar glomerular sun kasance a cikin kewayon al'ada, wanda ke nuna cewa EGCG yana da kyakkyawan bayanin tsaro.