A cikin 1976, lokacin da masu bincike suka fara nazarin abubuwan chlorinated na sucrose, da gangan sun gano wani fili mai tsananin za?i, sucralose, wanda aka ?auka a matsayin muhimmiyar nasara a fagen kayan zaki, saboda sucralose ba kawai mai da?i ba ne, har ma yana da ?arfi, dacewa don amfani da abinci da abubuwan sha. A cikin 1980s, sucralose ya wuce gwaje-gwajen aminci da yawa, gami da nazarin toxicological da gwaji na asibiti, yana nuna amincin sa a cikin mutane a cikin allurai da aka ba da shawarar, kuma a cikin 1991, an fara yarda da sucralose a Kanada don amfani dashi azaman ?ari na abinci. Hukumar Abinci da Magunguna ta Amurka (FDA) ta amince da sucralose a matsayin babban mai zaki ga abinci da abubuwan sha, tare da ci gaban fasahar samarwa, ana rage farashin samar da sucralose a hankali, yana mai da shi gasa a kasuwa, kuma ana amfani da shi sosai a cikin kayan gasa da abin sha. A cikin 'yan shekarun nan, an ?ara fadada filayen aikace-aikacen sucralose, kamar ruwan sigari e-cigare, filin magani, abinci mai aiki da sauransu. Daga cikin su, sigari na lantarki saboda yanayin aiki na yanayin zafi na musamman, amfani da sucralose shima ya bambanta da abincin gargajiya.

Matsayin sucralose a cikin e-cigare

Sucralose, a matsayin mai za?i na e-cigare ruwa, yana da fa'ida a bayyane kamar za?i da sauri, babban za?i, da za?i na halitta ba tare da barin za?i ba. A lokaci guda kuma, rashin amfani kuma sun shahara, ha?arin manna core yana da yawa a ?ar?ashin babban adadin adadin, kuma bazuwar thermal na iya faruwa a babban zafin jiki, yana haifar da abubuwa masu cutarwa, irin su hydrogen chloride (HCl) da maha?an chloral. Bugu da ?ari, ions chloride na iya yin hul?a tare da wayoyi masu dumama ?arfe, wanda ke haifar da hazo mai nauyi, yana haifar da ha?arin lafiya.

A cikin 2015, Lu Xialian (aikin bazuwar thermal na sucralose) da sauransu daga Jami'ar Sun Yat-sen sun yi amfani da fasahar TG-DSC-FTIR don bincika aikin bazuwar thermal na sucralose, kuma sakamakon ya nuna cewa sucralose zai fara bazuwa a 120 ℃, samar da HCl, H2O da CO2. Tun da abun ciki na sucralose a cikin abinci yana da ?an?anta, sucralose zai fara bazuwa. Hydrogen chloride da ake samu ta hanyar rubewarsa yana narkar da shi a cikin ruwa a matsayin hydrochloric acid, wanda shine babban bangaren acid na ciki, kuma ana iya la'akari da cewa sucralose ba ya haifar da abubuwa masu cutarwa ga jikin mutum a yanayin dafa abinci mai zafi kasa da 200 ℃. Saboda yanayin aiki mai zafi na musamman (> 200 ° C), ruwan sigari har yanzu yana da rashin tabbas idan aka kwatanta da dafa abinci na gargajiya. A cikin 2019, Rachel El-Hage (Mai guba mai guba sakamakon sucralose da aka ?ara zuwa ruwan sigari na lantarki et al. sun yi amfani da GC-MS don gano sakin aerosol na e-cigare tare da ?ara sucralose, kuma ta sami ruwayoyin chloropropanol guda biyu a cikin sakin aerosol, da adadin chloropropanol na shekara guda tare da sucralose. K. Duell (Sucralose-Enhanced Deradation na Electronic Cigarette Liquidsduring Vaping) et al. sun wuce 1H NMR spectroscopy, ion chromatography da gas chromatography hade tare da taro spectrometry da harshen wuta ionization ganowa ya bayyana cewa sucralose yana haifar da samar da yiwuwar cutarwa organochlorides da cacycles cacycles. atomized.

A cikin 2024, ma'aikatan masana'antar E-cigare Yan (Tasirin sucralose da neotame akan amincin hazo na ?arfe a cikin sigari na lantarki da sucralose an kwatanta su tsakanin masu zaki guda biyu, neotame da sucralose, akan sakin ?arfe mai nauyi daga sigari na e-cigare da tasirin su akan ayyukan sel. Sakamakon ya nuna cewa a ?ar?ashin yanayi iri ?aya ne, yana da yuwuwar ha?akar ?arfe na ?arfe. Babban tasiri akan ayyukan tantanin halitta

A ta?aice, sucralose yana da ?an kwanciyar hankali a cikin abinci kuma yana da ?arancin ha?arin lafiya. A cikin ruwan sigari na e-cigare, ba za a iya watsi da sucralose don ha?aka ?an?ano ba, ?an lokaci mafi wahala don maye gurbin, ba za a iya la'akari da ha?arin aminci da ke biyo baya ba, amma ajiye kashi don yin magana game da guba shine ?an damfara, yadda ake amfani da sucralose a hankali shine mayar da hankali. Bugu da kari, har yanzu akwai bayanan asali da yawa da suka ?ace, kuma har yanzu yana da mahimmanci a ci gaba da gudanar da bincike na gwaji a hankali kuma a hankali a inganta.