Tasirin mannose akan sukarin jini kadan ne, kuma ana iya cewa "kusan ba shi da wani tasiri" akan matakan sukarin jini. Wannan shine babban bambanci tsakaninsa da yawancin sauran masu ciwon sukari irin su glucose.

Ga cikakken bayani:

Daban-daban hanyoyin metabolism:

Glucose: shine babban tushen kuzari ga jiki. Hanji yana sha sosai (kusan 100%), yana shiga cikin jini (yana ha?aka sukarin jini), kuma ana ?auka, amfani da shi, ko adana ta sel tare da taimakon insulin (kamar glycogen, mai).

Mannose: Ko da yake shi ma monosaccharide ne (sukari shida na carbon), hanyar rayuwa a cikin jiki ya bambanta da glucose.

?ar?ashin shayarwa: ?arfin ?wayar hanji na mannose ya yi ?asa da na glucose (kimanin kashi 20 kawai ko ?asa).

Ba a dogara da insulin ba: Bayan an shiga cikin hanta, yawancin mannose yana samun phosphorylated zuwa mannose-6-phosphate ta takamaiman enzymes (musamman mannose kinases).

Juyawa zuwa Fructose-6-phosphate: Mannose-6-phosphate an canza shi zuwa Fructose-6-phosphate ta phosphomannose isomerase.

Shigar da hanyar glycolysis: Fructose-6-phosphate samfuri ne na tsaka-tsaki a cikin hanyar glycolysis wanda za'a iya ?ara ha?akawa don samar da makamashi. Makullin shine wannan tsarin jujjuyawar yana ?etare mahimman matakai kamar glucokinase da glucose-6-phosphate, kuma baya dogara ga aikin insulin. "

Abubuwan da ba su da ?arfi na insulin:

?

Saboda kasancewar mannose da kansa ba shine babban abin da ke motsa sukarin jini ba (tare da ?aramin adadin shiga cikin jini da hanyoyin rayuwa daban-daban), baya ha?aka ?wayoyin beta na pancreatic don ?oye insulin kamar glucose. Bincike ya nuna cewa gudanar da mannose na baki ba ya ?ara yawan glucose na jini da matakan insulin.

Shaidar asibiti da gwaji:

?

?ananan binciken da aka gudanar a cikin mutane masu lafiya da masu ciwon sukari na 2 sun nuna cewa ko da a cikin nau'i mai yawa (kamar 0.2 g / kg nauyin jiki, wanda yake daidai da 14 g na mutum 70), mannose na baki bai haifar da gagarumin canje-canje a cikin matakan glucose na jini ba.

Gwajin dabbobi kuma sun nuna a kai a kai cewa mannose baya ?ara yawan sukarin jini.

Takaitacciyar dalilan da yasa mannose ke da ?an tasiri akan sukarin jini:

?

?ar?ashin shayarwa: Mafi yawan mannose da aka ci ba a sha kuma ana amfani da su kai tsaye ko kuma suna fitar da su ta hanyar ?wayoyin hanji.

Hanyar rayuwa ta musamman: Sashin da aka sha yana canzawa da sauri zuwa fructose-6-phosphate a cikin hanta ta hanyar hanyar insulin mai zaman kanta kuma yana shiga glycolysis, yana guje wa kewayawa kai tsaye azaman glucose na jini (glucose).

Insulin mara kuzari: Rashin ingantaccen kuzari na sukarin jini, don haka baya haifar da mugunyar insulin.

Muhimmiyar Sanarwa:

?

Kashi: Abubuwan da ke sama sun dogara ne akan ?arin allurai na al'ada (yawanci ana amfani da su don dalilai na kiwon lafiya na urinary, kusan gram 1-2 kowace rana) da wasu allurai na bincike (kamar 0.2g/kg). A cikin ka'idar, manyan allurai masu yawa na iya haifar da nauyin nauyi daban-daban na rayuwa, amma yawanci ba a amfani da su don wannan dalili.

Za?i: Za?i na mannose kusan kashi 70 cikin ?ari na sucrose ne, amma a wasu lokuta ana ambaton shi a matsayin mai yuwuwar “mai zaki mai ?arancin glycemic index” saboda baya shafar sukarin jini kuma yana raguwa. Amma farashinsa da ?an?anon sa (da ?an daci) a matsayin mai zaki yana iyakance aikace-aikacensa da yawa.

Babban amfani: A halin yanzu, babban aikace-aikacen mannose yana dogara ne akan ikonsa na tsoma baki tare da ha?in gwiwar kwayoyin cuta (mafi yawan Escherichia coli) zuwa kwayoyin epithelial na urinary tract, don rigakafi da maganin cututtuka na urinary fili (UTIs). Halayen halayen sa na sukari na jini sun sa ya zama za?i mai aminci ga masu ciwon sukari ko mutanen da ke da ikon sarrafa sukarin jini lokacin da suke bu?atar hana kamuwa da cutar urinary (ba shakka, har yanzu suna bu?atar bin shawarar likita).

Bambance-bambancen mutum da shawarwari tare da likitoci: Kodayake hanyoyin rayuwa sun ?ayyade cewa baya shafar sukarin jini, ana iya samun bambance-bambance tsakanin mutane. Idan kana da ciwon sukari mai tsanani ko wasu cututtuka na rayuwa, yana da kyau a tuntu?i likita kafin amfani da mannose a matsayin kari.

?arshe:

Mannose sukari ne na musamman wanda, saboda ?arancin sha na hanji da ke?antacce, hanyar rayuwa mai zaman kanta ta insulin a cikin hanta, da wuya yana haifar da ha?akar matakan sukari na jini kuma baya ha?aka fitar insulin. Wannan ya sa ya fi aminci ga mutanen da ke bu?atar sarrafa sukarin jini (kamar masu ciwon sukari) fiye da sauran masu ciwon sukari, musamman ma lokacin da ake amfani da shi don hana kamuwa da cututtukan urinary.