Vitamin B3, wanda kuma aka sani da niacin, bitamin ne mai narkewa da ruwa wanda ke aiwatar da ayyuka iri-iri masu mahimmanci a cikin jiki. Nazarin farko ya nuna cewa bitamin B3 yana shiga cikin tsarin samar da makamashi na jiki, yana ha?aka metabolism na ?wayoyin fata, kuma yana da wani tasirin antioxidant.

Ciwon hanta mai kitse ba tare da barasa ba (NAFLD), ita ce mafi yawan cututtukan cututtukan hanta na yau da kullun a kasar Sin, akwai marasa lafiya sama da miliyan 150 a kasar Sin, wanda 10-20% daga cikinsu za su kara girma zuwa steatohepatitis mara-giya (NASH), galibi yana bayyana ta kumburi da lalacewar hanta, sau da yawa tare da fibrosis. NASH yana ci gaba da sauri kuma yana da ha?ari mafi girma na tasowa cututtuka masu tsanani kamar cirrhosis da ciwon hanta.

Kwanan nan, Masu bincike daga Makarantar Kiwon Lafiyar Jama'a a Jami'ar Sun Yat-sen sun buga wata takarda a cikin mujallar JAMA Network Open mai suna "Dietary Niacin Intake and Mortality between Individuals With Nonalcoholic. Fatty Liver Disease" takarda bincike.

Nazarin ya nuna cewa kari tare da bitamin B3, ko raguwa a cikin ha?arin duk abin da ke haifar da mutuwa a cikin marasa lafiya tare da cututtukan hanta mai ?iba, an danganta shi da raguwar 30% a cikin ha?arin duk abin da ke haifar da mutuwa a cikin mahalarta tare da mafi girman ci (≥26.7mg / rana) idan aka kwatanta da mahalarta tare da mafi ?arancin abinci (≤18.4mg / rana).

A cikin wannan binciken, masu binciken sunyi nazarin ha?in gwiwa tsakanin cin abinci na bitamin B3 da kuma hadarin duk-sakamakon mutuwa a cikin marasa lafiya da cututtukan hanta marasa shan taba ta hanyar tattara abincin bitamin B3 na abinci daga Cibiyar Nazarin Kiwon Lafiya da Abinci (NHANES) na 4,315 NAFLD marasa lafiya tare da matsakaicin shekaru 53 shekaru.

An raba mahalarta zuwa kungiyoyi uku dangane da cin abinci na bitamin B3: ?ananan ?ungiyoyi masu cin abinci (≤18.4mg / rana), ?ungiyar masu ci gaba (18.5-26.6mg / rana) da kuma babban rukuni (≥26.7mg / rana).
A cikin tsawon lokacin bin diddigin shekaru 8.8, an sami adadin mutuwar 566, 197 daga cikinsu an danganta su da cututtukan zuciya.

Binciken ya gano cewa mahalarta masu cin abinci mafi girma suna da kashi 30 cikin 100 na kasadar duk abin da ke haifar da mutuwa idan aka kwatanta da mahalarta tare da mafi ?arancin abinci.

Bugu da ?ari, mahalarta masu cin abinci mafi girma sun sami raguwar kashi 35 cikin 100 na ha?arin mutuwar zuciya da jijiyoyin jini, amma wannan ba shi da mahimmanci.

?arin bincike ya sami muhimmiyar ma'amala tsakanin cin abinci na bitamin B3 da ha?arin ciwon sukari da duk abin da ke haifar da mutuwa, tare da raguwa mai yawa a cikin mace-mace a marasa lafiya marasa ciwon sukari idan aka kwatanta da masu ciwon sukari.

A cewar masu binciken, niacin yana daya daga cikin abubuwan da ke haifar da hadawar NAD kuma ya zama muhimmiyar manufa don rigakafi da magance cututtukan hanta. Binciken shiga tsakanin jama'a ya kuma nuna cewa niacin na iya inganta hanta mai kitse da rage kitsen hanta. A cikin bincike na yau da kullun, an gano niacin don hanawa da juyar da steatosis na hanta da kumburi, da hana fibrosis. Ana samun wa?annan tasirin ta hanyar rage damuwa na oxidative, hana diacylglyceryl acyltransferase 2 da aikin NADPH oxidase, da sauran hanyoyin da za a iya yiwuwa.

Yana da kyau a ambaci cewa a cikin Satumba 2023, Masu bincike daga Makarantar Kiwon Lafiyar Jama'a a Jami'ar Sun Yat-sen sun buga takarda a cikin mujallar Nutrients mai taken "?ungiya tsakanin Abincin Niacin Abincin Abinci da Cutar Hanta Nonalcoholic: NHANES 2003-2018" takarda bincike.

Binciken ya nuna cewa karin bitamin B3 yana da ala?a da ?ananan ha?arin cututtukan hanta mai ?iba, tare da wa?anda ke da mafi yawan shan niacin (≥29.2mg/rana) suna da ?arancin ha?ari na 31% na cututtukan hanta maras barasa idan aka kwatanta da wa?anda ke da mafi ?arancin niacin (≤16.3mg / rana).

A hade tare, sakamakon ya nuna cewa karin bitamin B3 yana da ala?a da ?ananan ha?arin cututtukan hanta mai kitse mara barasa da kuma rage ha?arin duk abin da ke haifar da mutuwa a cikin marasa lafiya da cututtukan hanta mai ?iba. Ana bu?atar ?arin bincike don tabbatar da mafi kyawun kashi na bitamin B3 don rage ha?arin duk abin da ke haifar da mutuwa a cikin marasa lafiya tare da NAFLD.