Ciwon hanta na barasa (ALD), cuta ce ta hanta da ake fama da ita ta hanyar shan ruwa mai yawa na dogon lokaci, yana daya daga cikin cututtukan hanta da aka saba gani a kasar Sin, wadanda suka hada da hanta mai kitse, cutar hanta ta barasa, fibrosis na barasa da cirrhosis na giya. A cikin 'yan shekarun nan, yawan cututtukan hanta na barasa ya nuna karuwa a cikin kasar Sin.

A ranar 2 ga Yuli, 2024, Liu Zhihua na Jami'ar Tsinghua, Wang Hua na Jami'ar Kiwon Lafiya ta Anhui, Yin Shi na Jami'ar Kimiyya da Fasaha ta kasar Sin da sauran masu bincike sun buga labarin mai taken "Fiber abinci yana rage raunin hanta ta barasa ta hanyar" a cikin mujallar Cell Host & Microbe "Bacteroides acidifaciens and ammonia dectoxification".

An samo abinci mai wadata a cikin fiber mai narkewa don ?ara yawan B. accidifaciens da kuma rage raunin hanta da barasa ke haifarwa a cikin mice.

A kan tsarin, B.accifaciens yana daidaita tsarin metabolism na bile acid ta hanyar bile saline hydrolysis enzyme (BSH). ?ara ha?akar bile acid wanda ba a ha?a shi ba yana kunna hanyar FXR-FGF15 a cikin hanji, yana kare aikin shinge na hanji, yana inganta bayyanar ornithine aminotransferase (OAT) a cikin hepatocytes, kuma ta haka yana inganta metabolism na tara ornithine a cikin hanta zuwa glutamate. Samar da albarkatun kasa don lalata hanta da rage lalacewar hanta.

wannan binciken, masu binciken sun fara haifar da cututtukan hanta na barasa a cikin samfurin linzamin kwamfuta kuma sun yi nazarin tasirin fiber na abinci akan cututtukan hanta na barasa a cikin mice ta hanyar ha?aka fiber mai narkewa da maras narkewa.

Sakamakon ya gano cewa ?arar fiber na abinci mai narkewa yana inganta ha?akar cututtukan hanta na barasa a cikin mice, gami da rage steatosis hanta da rage yawan adadin neutrophils na hanta, yayin da fiber na abinci mai narkewa ba shi da tasiri mai mahimmanci.

Saboda fiber na abinci na iya tasiri sosai ga microbiota na gut, masu binciken sun kara nazarin ko ha?akar cututtukan hanta na barasa ya kasance yana iya haifar da microbiota na gut ta hanyar dabarun dasa microbiota.

Bayan dasawa, an gano cewa dasawa da microflora na berayen da ke ciyar da fiber mai narkewa mai narkewa ya rage ?wayar alanine aminotransferase (ALT) da matakan aspartate aminotransferase (AST), yayin da rage steatosis na hanta da matakan kumburi, yana ba da shawarar cewa fiber na abinci mai narkewa na iya rinjayar ci gaban ALD ta hanyar sake fasalin abun da ke ciki na microflora na hanji.

Binciken ya nuna cewa fiber mai narkewa mai narkewa ya inganta ?wayar hanta necrosis, hanta steatosis da kumburi a cikin ?irar linzamin kwamfuta na cututtukan hanta, da kuma rage matakin ammoniya na jini da damuwa na oxyidative, yana nuna muhimmiyar rawar da fiber mai narkewa mai narkewa a cikin rigakafin cutar hanta ta barasa.

Yana da mahimmanci a lura cewa ana ba da shawarar manya gaba?aya su cinye gram 25-30 ko fiye na fiber na abinci kowace rana, amma yawancin mutane ba sa biyan shawarwarin abinci. Dukan hatsi, 'ya'yan itatuwa da kayan marmari sune tushen tushen fiber na abinci kuma suna iya samar da wasu mahimman ma'adanai masu mahimmanci.

A ta?aice, sakamakon ya nuna cewa cin abinci mai wadata a cikin fiber mai narkewa mai narkewa zai iya inganta ciwon hanta da ke haifar da barasa a cikin ?irar linzamin kwamfuta yayin da yake kare mutuncin shingen hanji. Wannan binciken yana da takamaiman ?imar asibiti da mahimmancin zamantakewa.

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