Yisti beta-glucan shine polysaccharide mai aiki wanda aka samo daga bangon tantanin halitta na yisti. A cikin 1941, Dokta Pillemer ya gano wani abu a bangon kwayar yisti wanda ke ?arfafa rigakafi. A cikin 1961 Riggi ya gano wannan sinadari mai aiki a cikin yisti glycan azaman beta-glucan [1]. Abubuwan da ake amfani da su na beta-glucan na yau da kullun sun ha?a da hatsi, fungi, ciyawa, da sauransu, saboda jiki ba zai iya ha?awa ko ?oye beta-glucan kanta ba, dole ne duniyar waje ta ?ara ta.

Baya ga β-glucan da bangon cell yisti akwai kuma mannose mai narkewa da ruwa da ?aramin adadin chitin, β-glucan ya ?auki kashi 30% zuwa 60% na busassun nauyin bangon tantanin halitta, a cikin bangon ciki na bangon tantanin halitta, yana cikin tsarin polysaccharide, babban aikin physiological shine don kula da ?arfin injin bangon tantanin halitta. Misaki et al. ya gano cewa tsarin yisti β-glucan ya ?unshi β-1, 3-bond, kuma ya ?unshi wani yanki na β-1, 6-bond sharu?an.

Ingancin immunomodulatory na yisti beta-glucan ya dogara da madaidaicin niyya, ikonsa na ?aure takamaiman masu kar?a akan saman ?wayoyin rigakafi, yayin ha?aka ayyukan phagocytosis na macrophages. Wannan tsari da sauri yana inganta martanin rigakafi na jiki kuma yana kiyaye ma'auni mafi kyau na tsarin rigakafi.

Beta-glucan yana aiki da farko ta hanyar ?aure nau'ikan masu kar?ar beta-glucan guda uku [4]: ??(1) Mai kar?ar Dectin-1; (2) CR3; (3) Sauran masu kar?a, gami da mai kar?a na scavenger da LacCer. Lokacin da yisti β-glucan ya shiga jikin mutum kuma ya ?aure ga mai kar?a, zai ?ara phosphorylation na intracellular immune receptor tyrosine motif (ITAM) da Syk, kuma ya kunna hanyar PI3K / Akt, wanda a ?arshe ya haifar da phagocytosis, mutuwar microbial da cytokine saki, don hana ?wayoyin cuta na waje. Sannan kuma kuna samun tasirin rigakafi.

Amfanin lafiyar fata na beta-glucan yana nunawa a cikin abubuwa masu zuwa [6]:

1) ?arfin antioxidant: β-glucan yana da kaddarorin antioxidant, wanda zai iya hana samar da superoxides da sauran nau'in oxygen mai amsawa (ROS) da kuma rage lalacewar danniya na oxidative ga fata.

2) Sakamakon moisturizing: Tare da nauyin nauyin kwayoyin halitta, β-glucan yana da ?arfin ha?in ruwa mai ?arfi, wanda zai iya ha?awa da kwayoyin ruwa yadda ya kamata a saman sel fata, hana ?awancen ruwa, da rage asarar ruwa ta hanyar epidermis (TEWL). Bugu da ?ari, yana samar da fim mai kariya a saman fata, yana taimakawa wajen kula da danshi da laushi a cikin fata.

3) Gyaran fata da ?arfin warkarwa: Seo et al. gano cewa daban-daban tushen beta-glucan na iya inganta ?aura na keratinocytes na mutum (HaCaT) da fibroblasts na fata na mutum (HDFa), da kuma hanzarta rufe raunuka da sake dawo da epithelialization a cikin ?irar linzamin kwamfuta [7]. Bugu da ?ari, abubuwan da ke hana kumburi da ha?akar ha?akar beta-glucan suna taimakawa rage kumburi da ja da kuma kwantar da fata mai kumburi. Wani bincike a cikin Jarida na Therapeutic Dermatology ya nuna cewa beta-glucan wani tasiri ne mai mahimmanci ga maganin ?wayar cuta mai laushi (eczema) [8].

4) Abubuwan da ke hana tsufa: Beta-glucan yana taimakawa wajen rage alamun tsufa, kamar wrinkles da sagging. Yana ha?aka ha?akar collagen da sauran abubuwan ha?in matrix na fata (ECM), yana ha?aka kauri da elasticity na fata.

Bugu da ?ari, beta-glucan yana da rawar da ke daidaita flora na hanji, rage cholesterol, maganin gajiya, lafiyar kashi da sauransu.

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