A fagen binciken lafiyar hanji, Polydextrose ya da?e ana rarraba shi azaman fiber na abinci na yau da kullun mai narkewa da ruwa. Koyaya, binciken da aka samu da yawa a cikin 'yan shekarun nan ya nuna cewa wannan kwayar halitta ta roba ba da gangan ba daga glucose shine ainihin "mai kunnawa" wanda ke sake fasalin microecology na hanji ta hanyar sau uku na "tsarin dankon danko - daidaitaccen ciyar da microbiota - metabolite cascade dauki". Sabon binciken a cikin Nature Gastroenterology a cikin 2024 yana nuna cewa cin abinci na yau da kullun na 10-15g na polyglucose zai iya ha?aka amincin shingen hanji da kashi 37% kuma ya rage matakin IL-6 mai kumburi da kashi 29%. Wannan binciken ba wai kawai ya juyar da fahimtar al'ada ba har ma yana haifar da sauye-sauyen aikace-aikacen ladabtarwa daga masana'antar abinci zuwa magungunan asibiti.

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Mai ri?e da Kudaoplace0 Babi na 1 ?ididdigar Kimiyya: "Dukkanin sashin narkewar jiki basira" na kwayoyin halitta

Youdaoplaceholder0 1.1 Nakasar danko: "amsar hankali" daga ciki zuwa hanji

Bambancin polydextrose ya ta'allaka ne a cikin canjin danko mai amsawar Ph.

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Youdaoplaceholder0 Ciki ? (pH 1.5-3.0): Molecular sar?o?i suna giciye-dangane ta hanyar hydrogen bond don samar da uku-girma cibiyar sadarwa tsarin, danko sabulu har zuwa 1500 mPa·s, slows saukar da ciki fanko kudi har zuwa 45% (idan aka kwatanta da kawai 20% rage cin abinci).

Youdaoplaceholder0 ?ananan hanji ? (pH 6.0-7.4): Ha?in hydrogen sun karye ka?an, an rage danko zuwa 400 mPa·s, kuma adsorption na bile acid yana rage ?wayar cholesterol da 18% ba tare da shafar sha na gina jiki ba;

Youdaoplaceholder0 Colon ? (pH 7.0-7.5): An fara fermentation na microbial, danko ya tarwatse zuwa ?asa da 50 mPa·s, an saki ?an gajeren sarkar fatty acid (SCFAs), tare da ?wayar butyric acid yana ?aruwa da sau 3.2, kai tsaye yana kunna gyaran ?wayar hanji (Figure 1 cell).

Youdaoplaceholder0 Fasaha Breakthrough: DSM's SmartVisc? fasaha na iya ke?ance danko mai lankwasa don sassa daban-daban ta hanyar daidaita ma'aunin polymerization (darajar DP), kamar nau'in nau'in G da aka tsara musamman don marasa lafiya da ciwon gastroesophageal reflux, wanda ke samar da fim na kariya ta jiki tare da danko har zuwa 2000 m cikin ciki.

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Mai ri?e da kudaoplace0 1.2 Tsarin Microbiota: Daga "ciyarwar bakan" zuwa "ribar da aka yi niyya" ?

Magungunan rigakafi na al'ada sau da yawa suna tayar da duk microbiota, yayin da polydextrose yana nuna madaidaicin ikon sarrafawa:

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Youdaoplaceholder0 Hani na sama: Babban yanayin danko yana haifar da shinge na jiki a cikin hanji na kusa, yana hana mannewar kwayoyin cuta (kamar Escherichia coli), rage yawan kamuwa da cutar ta hanyar 52%;

Youdaoplaceholder0 Yaduwa a ?asa: Oligosaccharides an fi son amfani da gutsuttsura ta hanyar ?wayoyin cuta masu amfani kamar Bifidobacterium da Roseella, kuma yawansu ya karu da 68% bayan makonni 8 na sa baki (bisa ga tsarin metagenomic);

Youdaoplaceholder0 Metabolic Synergy: Butyric acid da aka samar yana kunna mai kar?ar GPR109A, yana haifar da bambance-bambancen tantanin halitta T, kuma yana ha?aka ma'auni na rigakafi na hanji zuwa 0.91 (?ofar lafiya> 0.85).

Youdaoplaceholder0 Babi na 2 Guguwar Aikace-aikacen: Ayyukan Ketare Daga Tebur zuwa Gadajen Asibiti

Youdaoplaceholder0 2.1 Masana'antar Abinci: "Injin da ba a iya gani" tare da ingantattun ayyuka

Youdaoplaceholder0 Baking Juyin Juya Hali: ?ungiyar Meiji ta Japan ta ha?aka kukis-sucrose ta hanyar amfani da damar ri?e ruwa (8.3g ruwa / g) da kwanciyar hankali na thermal (ha?uri zuwa 220 ° C) na polyglucose, yana rage canjin glucose na jini bayan 41%.

Youdaoplaceholder0 Innovation Abin Sha : Nongfu Spring's Intestinal Water Sparkling Water, wanda ke amfani da kayan samar da iskar gas na polyglucose don kawar da ma?ar?ashiya ba tare da haushi ba, an sayar da fiye da kwalabe miliyan 8 a cikin watan farko a kasuwa;

Youdaoplaceholder0 Nasarar Maye gurbin Abinci: Soylent a Amurka yana amfani da dabarar ?an?o?i-girma don tsawaita jinkirin sakin makamashi zuwa sa'o'i 6 da ha?aka juriyar masu tseren marathon da kashi 23%.

Youdaoplaceholder0 2.2 Abinci na asibiti: "garkuwar shingen hanji" ga marasa lafiya na ICU ?

Nazarin RCT na asibitin Sir Run Run Shaw, Makarantar Magunguna, Jami'ar Zhejiang (n=204) ya nuna cewa:

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Youdaoplaceholder0 Rigakafin kamuwa da cuta: A cikin marasa lafiya na ICU da aka ha?aka tare da 15g na polydextrose kowace rana, abubuwan da ke faruwa na sepsis na enterogenous ya ragu da 44%;

Youdaoplaceholder0 Gyaran Mucosal : Plasma ligonin (alama ce ta karyewar hanji) matakan sun ragu da kashi 31% kuma yawan tantanin goblet ya karu da 39%;

Youdaoplaceholder0 Immunomodulatory : Matsalolin jini IgA ya karu da kashi 28%, kuma rabon tantanin CD4+/CD8+ T ya koma kewayon al'ada.

Mai ri?e da wurin zama0 Babi na 3 Juyin Juyin Fasaha: Daga ?irar Kwayoyin Halitta zuwa ?arfafa Gina Jiki na AI.

Youdaoplaceholder0 3.1 Gyara Tsarin: Bu?e Ke?ancewa akan bu?ata

Youdaoplaceholder0 Niyya danko : Ta hanyar gabatar da sar?o?in gefe na sorbitol, an ha?aka takamaiman nau'in polyglucose (nau'in C), wanda ?an?o?insa ya ragu sosai zuwa 10 mPa·s a pH 7.0, musamman ga mutanen da ke da ma?ar?ashiya;

Youdaoplaceholder0 Ingantacciyar al'ada: Roguet, Faransa, ?ullo da fasahar Probiocoat? microcapsule wanda ke tattara probiotics a cikin matrix polyglucose, yana ha?aka ?imar tsira daga 15% zuwa 92%.

Youdaoplaceholder0 3.2 Sirrin wucin gadi: Fasa ka'idojin sa baki na ke?a??en

Tsarin "Digital Twin na Intestine" wanda NutriAI, wani kamfani na Isra'ila ya gina, ya ha?u da shari'o'in 200,000 na bayanan furen hanji na ?an adam da ?irar kuzarin ruwa, wanda zai iya yin hasashen martanin mutum ga polydextrose:

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Youdaoplaceholder0 Ingantaccen Dose : Tsarin 8-12g/rana + fructooligosaccharides hadewar tsarin da aka ba da shawarar ga marasa lafiya na IBS sun rage yawan kumburin ciki da 67%;

Youdaoplaceholder0 Scene Fit : Babban tsarin motsa jiki mai ?arfi wanda aka ke?ance don 'yan wasa, wanda ke ?ara yawan ha?owar hanji da kashi 40% kuma yana guje wa rashin jin da?i na ciki yayin horo.

Youdaoplaceholder0 \ n \ n Babi na Hudu: Rikicin Masana'antu: ?ar?ashin ?arfafa ?wararrun Fasaha a Kasuwannin Dala Tiriliyan ?

Youdaoplaceholder0 4.1 Karfin Race: Kamfanonin Sin sun tsallake rijiya da baya

Mai ri?e da wurin zama0 Baolingbao Bio : Zuba jarin yuan miliyan 800 don gina tushen samar da polyglucose mafi girma a duniya, fasahar hada-hadar enzymatic don cimma tsafta 99.9%;

Youdaoplaceholder0 Hualixi Biotech ? : Ha?aka nano-fibrotic polyglucose, ?ayyadaddun ?a'idodin ?a'ida ya ?aru da sau 4, an sami amincewar abinci na likita na musamman na NMPA;

Youdaoplaceholder0 Tsarin Tsarin Mulki: DuPont yana ha?in gwiwa tare da Mayo Clinic don ci gaba da gwajin gwaji na asibiti na Phase III na polydextrose a cikin rigakafin ciwon daji na colorectal.

Youdaoplaceholder0 4.2 Kalubalen Fahimi: Rata daga Lab zuwa Kasuwar Jama'a

Duk da isassun hujjoji na kimiyya, binciken mabukaci ya nuna cewa:

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Youdaoplaceholder0 Ilimi Makaho tabo : 31% kawai na jama'a sun fahimci bambance-bambancen aiki tsakanin polydextrose da fiber na gama gari;

Youdaoplaceholder0 kuskuren kashi : 45% na masu amfani da kuskure sunyi imani cewa "?arin shine mafi kyau", wanda zai iya haifar da rashin jin da?i kamar kumburi;

Martanin Masana'antu na Youdaoplaceholder0: ?ungiyar Gina Jiki ta kasar Sin ta fitar da farar takarda kan aikace-aikacen Polydextrose, wanda ke kafa amintaccen kofa na 15g kowace rana.

Mai ri?e wurin zama0 Babi na 5 hangen nesa na gaba: Sake fasalta 'Smart Boundary' na Fibre

Youdaoplaceholder0 5.1 Brain-Gut Axis Breakthrough: A Molecular Bridge from Gut to Emotion ?

Sabbin gwaje-gwajen dabbobi a Cibiyar Fasaha ta California sun gano:

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Youdaoplaceholder0 Taimakon damuwa : Mice a cikin rukunin shiga tsakani na polyglucose sun ha?aka lokacin binciken su a cikin gwajin maze da 53%;

Youdaoplaceholder0 Mechanism tracing: Butyric acid yana kunna BDNF magana a cikin hippocampus ta hanyar shinge-kwakwalwa na jini, yana ha?aka yawan synaptic da 29%.

Youdaoplaceholder0 5.2 Ilimin Halittar Halittar Halittu: '?arshen Siffa' na zaruruwa

Kamfanin Ginkgo Bioworks a Amurka ya canza nau'in yisti ta amfani da fasahar CRISPR-Cas9 don ?oye "polydextrose-encoded" kai tsaye tare da ayyuka na musamman:

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Youdaoplaceholder0 Daidaitaccen niyya: Yana iya ha?aka ha?akar Achaemenia musamman, kuma yawanta yana ?aruwa da 80% a cikin nau'ikan kiba;

Youdaoplaceholder0 Smart Amsa: Gina firikwensin pH, daidaiton canjin danko ya inganta zuwa ± 5 mPa·s, ana tsammanin shigar da gwajin asibiti a 2026.

Youdaoplaceholder0 Kammalawa: Lokacin da Intelligence Intelligence ya hadu da Gut Ecology ?

Tafiyar kimiyya na polydextrose tarihin dawowa ne daga "samfurin masana'antu" zuwa "injiniya muhallin halittu". Yana gaya mana cewa ci gaba na gaskiya a cikin kiwon lafiya sau da yawa yakan samo asali ne daga zurfin rushewa da sake tsara kan iyakoki na ainihin kwayoyin halitta. Kamar dai yadda Jennifer Doudna wadda ta samu lambar yabo ta Nobel ta ce, "Biology na ilimin halitta yana koya mana cewa ana iya baiwa kwayoyin halitta damar yin tunani." A cikin wannan juyin juya halin fasaha na lafiyar hanji, polydextrose na iya zama wurin farawa kawai - lokacin da ?arin "kwayoyin hankali" suka shiga ya?in, ?an adam zai cimma daidaitattun matakan magance cututtuka na yau da kullun.