He kumuhana kama'āina a pa?akikī ke kō i ko mākou ola i kēlā me kēia lā. Mai ka sucrose ma?amau, fructose a hiki i ka D-mannose li?ili?i, i kēia lā, e kama?ilio mākou e pili ana i ka hōkū ha?aha?a akā hiki ke loa?a - D-mannose.

Hiki ke kani ?o D-mannose me kahi inoa hui ?ole, akā he hexose maoli ia i ?ike nui ?ia ma ke ?ano. ?A?ole like me ka sucrose a me ka fructose, ke hele mai nei ?o D-mannose i ka maka o ka lehulehu me kāna ?ono kū?oko?a a me nā pono olakino he nui. ?O kona ?ono ma kahi o 60% o ka sucrose, he kōpa?a ha?aha?a ha?aha?a ha?aha?a, no ka ?imi ?ana i ka mea?ai olakino no nā po?e o kēia wā, ?a?ole ia he koho maika?i.

?A?ole ?olu?olu wale ?o D-mannose, akā nani nō ho?i kāna waiwai noi. Ma ke kahua mea?ai, hiki ke ho?ohana ?ia e like me ka mea ?ono ha?aha?a ha?aha?a no ka hana ?ana i nā mea?ai olakino like ?ole; I ka manawa like, no kona antioxidant, anti-inflammatory a me nā waiwai ?ē a?e, e like me ka moisturizer a me nā mea anti-aging e ho?ohana nui ?ia i nā mea ho?onaninani. Ma ke kahua lapa?au, ua hō?ike kupanaha hiki, a me nā ha?awina ua hō?ike i ka D-mannose hiki ke hoemi inflammatory bowel ma?i, mālama rheumatoid arthritis, pale asthmatic airway aahu, a hiki i hō?ike i nā hopena maika?i i ka mālama 'ana i ka ma?i 'a?ai a me congenital glycosylation ma?i.

I nā makahiki i hala iho nei, me ka ho?omohala wikiwiki ?ana o ka biotechnology, ua lilo ke ?ano biological i ke ?ano kumu nui o ka hana D-mannose. Ke ho?ohana nei kēia ?ano i nā enzyme biological no ka ho?ololi ?ana i nā kōpa?a ?ē a?e (e like me D-fructose) i D-mannose, nona nā pōmaika?i o ka hana ki?eki?e, ka mālama ?ana i ke kaiapuni a me ke kumu kū?ai ha?aha?a.

Ma waena o nā enzyme biological, makemake ?ia ?o D-mannose isomerase ma muli o kona mana catalytic ki?eki?e. Eia nō na?e, ?o ka hapa nui o nā ha?awina mua i ho?ohana iā Escherichia coli ma ke ?ano he chassis cell no ka hana ?ana, kahi i ho?omaika?i ai i ka hana hana akā ua lawe pū mai i nā pilikia palekana. Ma hope o nā mea a pau, ?a?ole ?o E. coli kahi mea?ai-palekana, a ?o nā mea kemika i hana ?ia e hiki ke ho?opilikia i ka endotoxin. I mea e ho?oponopono ai i kēia pilikia, ua ho?omaka ka po?e ?epekema e ?imi i nā kānana ?oko?a palekana. ?O ka hope loa, ua koho lākou iā Bacillus subtilis e like me ka cell chassis hou. Ua ho?okipa nui ?ia ?o Bacillus subtilis ma muli o kāna mau ?ano o ka mea ?awa?awa, ?a?ohe pō?ino, ?oi aku ka maika?i o ka antibacterial, ?a?ole ma?alahi e noho a ?a?ole ma?alahi e hana i ka lā?au kū?ē. ?O ka mea nui a?e, ua ?ike nui ?ia ?o ia ma ke ?ano he "Generally Recognized as Safe" (GRAS) kānana e ho?okō nei i nā koi ho?oma?ema?e mea?ai.