Ua like ka ?ono o ka neotame me ka aspartame, me ka ?awa?awa ?ole a me nā mea ?ono ?ē a?e. ?O ka ?ono o ka neotame he 8000-10000 mau manawa o ka sucrose, ?o ia ka 8000 mau manawa o ka sucrose ma 5% momona a hiki i ka 10000 mau manawa o ka sucrose ma 2% ?ono. Wahi a ka GB2760-2011 Hygienic Standards for Food Additives, i hā?awi ?ia e Zhang Le?an ?O ke ?ano o ka ho?ohana ?ana o Newsweet he mau ?ano mea?ai a me nā mea inu, a ua kūpono ka nui o ka ho?ohana e like me nā pono hana. ?O ka mea ma?amau, loa?a nā mea inu i ka 8-17mg / L, a?o nā huahana mea?ai he 10-35mg / kg.

Ma ke ?ano he mea ?ono hana, ?a?ohe hopena maika?i ?ole o ka neotame i ke olakino kanaka a ho?okani i kahi kuleana kūpono a ho?olaha paha. I ka ho?omaka ?ana o Dekemaba 1998, ua waiho ?ia ka noi no ka ho?ohana ha?aha?a ha?aha?a o ka neotame ma ke ?ano he mea ?ono mea?ai ma ?Amelika Hui Pū ?Ia. Ua ?ae ?ia no ka ho?ohana ?ana i nā mea?ai a me nā mea inu a pau e ka US FDA ma Iulai 9, 2002. Ua ?ae ?o EU i kāna noi ma Ianuali 12, 2010.

?O ka ?ono ma?ema?e, hou a kūlohelohe, e like me ka aspartame, akā me ka palekana ki?eki?e;

He ki?eki?e ka ?ono, ma kahi o 8000 mau manawa o ka sucrose, a ?oi aku ka ha?aha?a o ke kumukū?ai o ka ?ono like ma mua o ka aspartame;

?O nā mea?ai i loko e ma?alahi i ke kino o ke kanaka;

?O ka ikehu ha?aha?a a i ?ole ka ikehu, loa?a no ka ma?i ma?i, non cariogenic, a hiki ke ho?oikaika i ka ho?onui ?ana o ka bifidobacteria;

?A?ole ia e ho?opō?ino i ka niho a i ?ole ka loli kōpa?a koko, e lilo ia i mea ?ono maika?i no ka mea?ai olakino.