?O ke kī kekahi o nā mea inu kaulana loa ma ka honua, ?oi aku ho?i ma Kina. ?A?ole inu wale ke kī ma Kina, akā he hō?ailona ho?i o ke ?ano ola a me ka mo?omeheu.

?O ka inu kī i mana?o ?ia he ?ano ola olakino no ka mea aia nā ?ano mea pono like ?ole, e like me catechins, tii polyphenols a me ka caffeine. He nui nā ha?awina i hō?ike ?ia e hiki i ke kī kī ke kāohi i ka ma?i kanesa, ho?olō?ihi i ke ola, ho?emi i ka pilikia o ke koko ki?eki?e, ka ma?i diabetes, ka ma?i pu?uwai a pēlā aku.

?O ka ma?i hānai momona ?ole (NAFLD) ke ?ano ma?amau o ka ma?i ate ma?i ma Kina, me nā ma?i ma mua o 150 miliona. I kēia manawa, ?a?ohe lā?au lapa?au i ?ae ?ia e mālama i ka ma?i ?a?ai momona ?ole, a hiki i nā mea ma?i ke ho?opili wale me nā loli ?ai a me ka ho?oikaika kino. No laila, he mea nui e ho?omohala i nā ho?olālā lapa?au hou.

I kēia mau lā, ua ho?opuka nā mea noi?i mai Kina Medical University i kahi pepa i kapa ?ia "Epigallocatechin gallate alleviates non-alcoholic fatty ate ma?i" i loko o ka puke pai Clinical Nutrition ma o ka inhibition o ka olelo a me ka hana o Dipeptide kinase 4 ".

Ua ho?opa?a ?ia kēia ha?awina ma o nā ho?okolohua ho?ā?o i ho?opa?a ?ia, nā ho?okolohua holoholona a me nā ho?okolohua in vitro e kōkua ana ?o EGCG, ka mea nui bioactive i loko o ke kī ?ōma?oma?o, i ka ho?omaika?i ?ana i ka momona momona, ECGC inhibits lipid accumulation, inhibits inflammation, regulates lipid metabolism, pale i ka pō?ino o ke ake, a ho?omaika?i i ka non-alcoholic fatty liver ma ke kāohi ?ana i ka ?ōlelo a me ka hana o dipeptidase 4.

?O Dipeptide kinase 4 (DPP4), kahi protease e ho?oka?awale ana i nā ?ano substrates ma ka ?ili o ke kelepona, ke hō?ili?ili nei i nā hō?ike e pili ana ka DPP4 i ka ho?omohala ?ana i ka NAFLD, me nā mea ma?i NAFLD e hō?ike ana i ka hana plasma DPP4 ki?eki?e ma mua o nā kānaka olakino.

I loko o kēia noi?i, ua kālailai nā mea noi?i i ka hiki ke kūpono o EGCG i nā po?e ma?i me ka NAFLD ma o nā ho?okolohua ho?okele randomized, nānā i ka ho?omaika?i ?ana o EGCG ma ke akepa?a o nā ?iole kumu ho?ohālike ma o nā ho?okolohua ho?ohālike holoholona, ????a nānā i ke ?ano o ka ho?omaika?i ?ana o EGCG i NAFLD ma o nā ho?okolohua in vitro.

I loko o ka randomized ho'ā?o lapa?au e pili ana i 15 i komo me NAFLD, EGCG ua hoopau ia e ka tii polyphenol papa, a ua ana 'ikepili ma ka baseline, 12 pule, a me 24 pule.

Ua ?ike ?ia nā hopena he ha?aha?a ha?aha?a loa ka momona o ka ate ma hope o 24 mau pule o ka mālama ?ana i ka EGCG i ho?ohālikelike ?ia me ka baseline, a ?elua o nā mea ma?i i kala ?ia i ka momona ma hope o ka pau ?ana o ka manawa mālama 24 pule. Eia hou, ua emi nui ka poai puhaka o na ma'i a me ka huina cholesterol nui ma hope o 24 pule.

Ua hō?ike ?ia ka loiloi ma hope o 24 mau pule o ka mālama ?ana i ka EGCG, ua ho?emi ?ia nā pae AST a ua ho?emi pū ?ia nā pae DPP4.

Ua hō?ike ?ia ka nānā ?ana o ka hana Renal i nā pae serum creatinine a me nā helu helu kānana glomerular i loko o ka laulā ma?amau, e hō?ike ana he ?ano palekana maika?i ?o EGCG.