He li?ili?i loa ka hopena o ka mannose i ke kō koko, a hiki ke ?ōlelo ?ia he "aneane ?a?ohe hopena" i ke ki?eki?e o ke kō koko. He ?oko?a nui kēia ma waena o ia a me ka hapa nui o nā kō e like me ka glucose.

Eia ka wehewehe kiko?ī:

?O nā ala metabolic like ?ole:

Glucose: ?O ia ke kumu nui o ka ikehu no ke kino. Ho?opili maika?i ?ia e ka ?ōpū (kokoke 100%), komo i ke kahe koko (ho?onui i ke kō koko), a lawe ?ia, ho?ohana ?ia, a mālama ?ia paha e nā cell me ke kōkua o ka insulin (e like me ka glycogen, momona).

Mannose: ?Oiai he monosaccharide (?eono kalapona kōpa?a), ?oko?a loa kona ala hele i loko o ke kino mai ka glucose.

Ha?aha?a ha?aha?a ha?aha?a: ?Oi aku ka ha?aha?a o ka ?ōpū o ka ?ōpū o ka mannose ma mua o ka glucose (ma kahi o 20% a i ?ole ka li?ili?i).

?A?ole hilina?i i ka insulin: Ma hope o ka komo ?ana i loko o ke akepa?a, ua phosphorylated ka hapa nui o ka mannose i mannose-6-phosphate e nā enzyme kiko?ī (ka nui o ka mannose kinases).

Ho?ololi i ka Fructose-6-phosphate: Ho?ololi ?ia ?o Mannose-6-phosphate i Fructose-6-phosphate e phosphomannose isomerase.

Ke komo ?ana i ke ala glycolysis: ?O Fructose-6-phosphate kahi huahana waena ma ke ala glycolysis hiki ke ho?ololi hou ?ia e hana i ka ikehu. ?O ke kī, ?o kēia ka?ina ho?ololi e kā?alo i nā ?anu?u ko?iko?i e like me ka glucokinase a me ka glucose-6-phosphate, a ?a?ole hilina?i i ka hana o ka insulin. ?

?A?ole ho?oulu i ka huna ?ana o ka insulin:

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Ma muli o ka mana?o ?a?ole ?o mannose ka mea ho?oulu nui i ke kō koko ki?eki?e (me ka li?ili?i o ke komo ?ana i ke kahe koko a me nā ala metabolic ?ē a?e), ?a?ole ia e ho?oulu nui i nā cell beta pancreatic e hūnā i ka insulin e like me ka glucose. Ua hō?ike ?ia ka noi?i ?a?ole i ho?onui nui ka ho?ohana waha ?ana o ka mannose i ke koko koko a me nā pae insulin.

Hō?ike ho?okolohua a me nā hō?ike ho?okolohua:

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?O kahi helu li?ili?i o nā ha?awina i mālama ?ia i nā po?e olakino a me nā ma?i ma?i diabetes type 2 i hō?ike ?ia ?oiai ma nā ?ano ki?eki?e (e like me 0.2 g/kg ke kaumaha o ke kino, ?o ia ka like me 14 g no kahi kanaka 70 kg), ?a?ole i ho?okumu ?ia ka mannose waha i nā loli ko?iko?i i nā pae glucose koko.

Ua hō?ike mau ?ia nā ho?okolohua holoholona ?a?ole ho?onui ka mannose i ke kō koko koko.

E hō?ulu?ulu i nā kumu no ka hopena li?ili?i o ka mannose i ke kō koko:

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Ha?aha?a absorption rate: ?A?ole komo ka hapa nui o ka mannose i ho?omo?a ?ia a ho?ohana pololei ?ia a ho?oku?u ?ia paha e ka ma?i bacteria o ka ?ōpū.

Alanui metabolic kū ho?okahi: Ho?ololi koke ?ia ka ?āpana i ho?opa?a ?ia i fructose-6-phosphate i loko o ke ake ma o ke ala kū?oko?a insulin a komo i ka glycolysis, e pale ana i ke kahe pololei ?ana e like me ke koko glucose (glucose).

?A?ole ho?oulu ?ia ka insulin: Ka nele o ka ho?oulu ?ana i ke kō koko, no laila ?a?ole ia e ho?oulu i ka huna ?ana o ka insulin.

Ho?olaha nui:

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?O ka hopena: Ho?okumu nui ?ia nā hopena i luna ma luna o nā kumu ho?ohui ma?amau (e ho?ohana mau ?ia no nā kumu olakino mimi, ma kahi o 1-2 grams i kēlā me kēia lā) a me kekahi mau koina noi?i (e like me 0.2g/kg). Ma ke kumumana?o, hiki ke ho?oulu ?ia nā koina ki?eki?e loa i nā kaumaha metabolic like ?ole, akā ?a?ole i ho?ohana pinepine ?ia no kēia kumu.

?O ka ?ono: ?O ka ?ono o ka mannose ma kahi o 70% ka nui o ka sucrose, akā i kekahi manawa ua ?ōlelo ?ia ?o ia he "mea ?ono ha?aha?a glycemic index sweeter" no ka mea ?a?ole pili ia i ke kō koko a ?emi ?ia. Akā ?o kona kumukū?ai a me kona ?ono (?awa?awa iki) ma ke ?ano he mea ?ono e kaupalena i kāna noi ākea.

Ho?ohana nui: I kēia manawa, ?o ka noi nui o ka mannose e pili ana i kona hiki ke keakea i ka ho?opili ?ana o ka bacteria (ka nui o Escherichia coli) i nā ?āpana epithelial tract, no ka pale ?ana a me ka mālama ?ana i nā ma?i ma?i urinary tract (UTIs). ?O kāna mau hi?ohi?ona pili i ke kō koko e lilo ia i mea palekana no ka po?e ma?i ma?i ma?i a i ?ole ka po?e me ka ho?omalu ?ana i ke kō koko ke pono lākou e pale i ka ma?i ma?i urinary (?oia?i?o, pono lākou e hahai i ka ?ōlelo a ke kauka).

?O nā ?oko?a o kēlā me kēia kanaka a me ke kūkākūkā ?ana me nā kauka: ?Oiai ua ho?oholo nā mīkini metabolic ?a?ole pili ia i ke kō koko, aia paha nā ?oko?a ma waena o nā kānaka. Inā loa?a iā ?oe ka ma?i diabetes ko?iko?i a i ?ole nā ??ma?i metabolic ?ē a?e, ?oi aku ka maika?i e nīnau i ke kauka ma mua o ka ho?ohana ?ana i ka mannose i mea ho?ohui.

Ka hopena:

He kō kūikawā ?o Mannose, ma muli o ka ha?aha?a ha?aha?a o ka ?ōpū absorption a me ka ?oko?a, ?o ke ala metabolic kū?oko?a kū?oko?a o ka insulin i loko o ke ake, ?a?ole hiki ke ho?onui i ke ki?eki?e o ke kō koko a ?a?ole ho?oulu i ka huna ?ana o ka insulin. ?Oi aku ka palekana o kēia no ka po?e pono e ho?omalu i ke kō koko (e like me ka po?e ma?i ma?i diabetes) ma mua o nā kōpa?a ?ē a?e, ?oi loa ke ho?ohana ?ia e pale i nā ma?i ma?i urinary.