Ma ka ?oihana ?oihana o ka mea?ai,vitamina Eua like ia me ka "poo ihe." ?O ka hapa nuivitamina?O nā hana ma?amau he coenzyme i nā hopena kemika, e pā?ani ana i kahi kuleana kōkua, a ?oko?a ka huaora E, me kona ikaika pono?ī e pale i ke olakino kanaka. No ka Vitamin Emomona-soluble?ohana huaora a he derivative ia o benzodihydropyrane me ke ?ano like a me ka hana biological, ?o ia ho?i me ka tocopherol a me ka tocotrienol. Ho?oka?awale ?ia kēlā me kēia hui i ?ehā subtypes, α, β, γ a me δ, e like me ka ?oko?a o ke kūlana methyl ma ke apo benzopyrane, he 8 mau ?ano, a ?o kēia mau isomers he mana antioxidant. ?O nā radical manuahi kahi papa o nā molekala pa?a ?ole me ka ho?oulu ?ana kemika ki?eki?e loa i hana ?ia i ke ka?ina o ka metabolism kino. Hiki i ke kukui Ultraviolet, ka pollution kaiapuni a me nā mea ?ē a?e o waho ke ho?oulu i ka hana ?ana o nā radical manuahi, a ?o ka mitochondria ho?i ke kahua o ka hana radical manuahi ke hana nā cell i ka metabolism aerobic e ho?olako i ka ikehu. ?O ka nui o nā radical manuahi e ho?oulu i ke ko?iko?i oxidative, ka mea e ho?ouka i nā macromolecules biological e like me lipids, proteins a me DNA i loko o nā cell, e hopena i ka pō?ino oxidative. I nā manawa ko?iko?i, hilina?i ka huaora E i kāna ?ano phenolic hydroxyl e hā?awi i nā ?ātoma hydrogen e pane me nā radical manuahi, e hō?emi ana i nā radical manuahi, e ho?opau i ka hopena kaulahao oxidative, a pēlā e pale ai i nā cell.

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?O ka momona-solubility o ka huaora E e ho?ohele maika?i ?ia i nā wahi momona i nā lipids, e like me nā membrane cell a me nā lipoproteins. Ma kēia mau pūnaewele, ho?opa?a ikaika ia i ka lipid peroxidation. Ke ho?ouka nā radical manuahi i ka momona polyunsaturatednā ?akika, e ho?oulu i ka hopena lipid peroxidation kaulahao e ho?opō?ino i nā membrane cell a me nā lipoproteins, hiki i ka vitamin E ke ho?ōki i ka hopena i ka ho?omaka ?ana a me ka ho?ouna ?ana i nā pae, e pale ana i nā lipids i loko o ka ?ōpū, ke koko, nā ?i?o a me nā membrane cell. I ka ?ōnaehana cardiovascular,vitamina Ehō?emi i ka hana ?ana o ka lipoprotein ha?aha?a ha?aha?a ha?aha?a oxidized ma o ka hopena antioxidant, e hō?emi ana i kona pō?ino i nā cell endothelial vascular, a laila pale i ka ho?okumu ?ana a me ka ho?omohala ?ana o ka atherosclerotic plaque. I ka manawa like, hiki i ka huaora E ke ho?oponopono i ka ho?onui ?ana a me ka ne?e ?ana o nā ?i?o ?i?o ma?ema?e vascular e mālama i ke ?ano ma?amau a me ka elasticity o nā kī?aha koko. He kuleana ko?iko?i ka Vitamin E i ka ho?oponopono ?ana o ke kino. Ho?oikaika ia i ka ho?onui a me ka ho?oka?awale ?ana o nā cell immune e like me T a me B lymphocytes, ho?onui i ka pilina ma waena o nā pūnaewele, a ho?onui i ka pane immune. I ka manawa like, komo ia i ka ho?oponopono ?ana i ka transduction hō?ailona cell immune, pili i ka huna a me ka hō?ike ?ana o nā cytokines, a ho?oponopono i ka pane immune. ?O nā kumu kumu maoli o ka huaora E, ?o ia ka aila mea kanu, nā nati, nā ?ano?ano, a me nā lau ?ōma?oma?o. ?O kēia mau kumu, ?oi aku ka waiwai o nā aila mea?ai i ka vitamina E, ka hapa nui ma ke ?ano o ka alpha-tocopherol. Eia kekahi, aia nā mea ho?ohui multivitamin E ma ka mākeke, me ka softgel, nā papa chewable a me nā creams, i kūpono i nā pono o nā hui like ?ole. Ma muli o ka ?ai ?ana o ka mea?ai mea?ai, ?o ka ?ai ?ana o ka huaora E no nā pākeke he 15 mg i kēlā me kēia lā (ana ?ia i ka alpha-tocopherol equivalent). Eia nō na?e, hō?ike ?ia ka ?ike noi?i maoli ?o ka awelika o ka nui o ka huaora E i ?ai ?ia e nā pākeke ma o kā lākou ?ai ?ana i kēlā me kēia lā he emi ma mua o 10 mg. Ua kuhikuhi kekahi mau ha?awina i loko o ka adjuvant therapy no kekahi mau ma?i e like me ka ho?opane?e ?ana i ka ?elemakule a me ka ho?omaika?i ?ana i ka cognitive impairment, supplementing 200-800 mg o ka huaora E i kēlā me kēia lā e loa?a kekahi hopena. Ma ke?ano laulā, palekana ka huaora E waha, akā hiki ke ho?onui i ka nui o ka lawe ?ana i ka wā lō?ihi (?oi aku ma mua o 1,000 mg i kēlā me kēia lā) i ka hopena o nā hopena ?ino e like me ke kahe koko. No laila, i ka wā e ho?ohana ai i nā mea ho?ohui vitamin E, he mea nui e hahai i ka ?ōlelo a?o a nā po?e loea e hō?oia i ka palekana a me ka no?ono?o o ka ho?ohui.