Ma ke kahua o ka noi?i olakino ?ōpū, ua ho?opa?a ?ia ?o Polydextrose ma ke ?ano he fiber dietary ma?amau. Eia na?e, ua hō?ike ?ia kekahi mau ha?awina holomua i nā makahiki i hala iho nei ?o kēia mole synthetic i polymerized randomly mai ka glucose he "mea pā?ani versatile" e ho?ololi hou i ka microecology intestinal ma o kahi ?ano triple o "dynamic viscosity regulation - precise feeding of the microbiota - metabolite cascade reaction". ?O ka noi?i hou loa ma Nature Gastroenterology i ka makahiki 2024 e hō?ike ana i ka lawe ?ana i kēlā me kēia lā o 10-15g o ka polyglucose hiki ke ho?onui i ka pono o ka pale ?ōpū e 37% a ho?emi i ka pae o ka mea inflammatory IL-6 e 29%. ?A?ole kēia ?ike e ho?okahuli wale i ka cognition ku?una akā hā?awi pū kekahi i kahi nalu noi?i cross-disciplinary mai ka ?oihana mea?ai a hiki i ka lā?au lapa?au.

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Youdaoplaceholder0 Mokuna 1 Decoding Science: ?O ka "Whole digestive tract Intelligence" o kahi mole ?

Youdaoplaceholder.

Aia ka ?oko?a o ka polydextrose i kāna ho?ololi viscosity Ph-responsive:

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Youdaoplaceholder0 ?ōpū ? (pH 1.5-3.0): Ho?opili ?ia nā kaulahao molekala ma o nā pa?a hydrogen e hana i kahi ?ōnaehana ?ekolu-dimensional, nā kopa viscosity a hiki i 1500 mPa·s, e ho?olohi i ka nui o ka hemo ?ana o ka ?ōpū a hiki i ka 45% (ho?ohālikelike ?ia me 20% wale nō o ka mea?ai ma?amau).

Youdaoplaceholder0 ?O ka ?ōpū li?ili?i ? (pH 6.0-7.4): Ua haki ?ia nā pa?a hydrogen, ho?emi ?ia ka viscosity i 400 mPa·s, a ?o ka bile acid adsorption e ho?emi i ka lawe ?ana o ka cholesterol ma 18% me ka ?ole o ka ho?opili ?ana i ka mea?ai;

Youdaoplaceholder0 Colon ? (pH 7.0-7.5): Ho?omaka ka microbial fermentation, hemo ka viscosity i lalo o 50 mPa·s, ho?oku?u ?ia nā ?akika momona pōkole (SCFAs), me ka pi?i ?ana o ka waikawa butyric e 3.2 manawa, ho?ōla pololei i ka ho?oponopono ?ana i ka epithelial cell intestinal.

Youdaoplaceholder0 Technology Breakthrough ? : Hiki i ka ?enehana SmartVisc? o DSM ke ho?opilikino i nā pihi viscosity no nā ?āpana like ?ole ma o ka ho?oponopono ?ana i ke ki?eki?e o ka polymerization (waiwai DP), e like me ke ?ano G-type formula i ho?olālā ?ia no nā po?e ma?i me ka gastroesophageal reflux, i hana i kahi ki?i?oni?oni pale kino me ka viscosity a hiki i 2000 mPa·s i loko o ka ?ōpū.

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Youdaoplaceholder0 1.2 Ho?oponopono Microbiota: Mai ka "hānai ākea ākea" a i ka "loa?a i mana?o ?ia" ?

Ho?oulu pinepine nā prebiotic ku?una i nā microbiota āpau, ?oiai ke hō?ike nei ka polydextrose i nā mana ho?oponopono pololei:

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Youdaoplaceholder0 Upstream inhibition ? : ?O ke kūlana viscosity ki?eki?e e hana i kahi pale kino i loko o ke kolonā kokoke, e kāohi ana i ka ho?opili ?ana o nā bacteria pathogenic (e like me Escherichia coli), e hō?emi ana i ka helu colonization pathogen e 52%;

Youdaoplaceholder0 Downstream proliferation ? : Ua ho?ohana maika?i ?ia nā ?āpana oligosaccharide e nā ma?i bacteria maika?i e like me Bifidobacterium a me Roseella, a ua ho?onui ?ia ko lākou nui e 68% ma hope o 8 mau pule o ka hana (e pili ana i ka metagenomic sequencing);

Youdaoplaceholder0 Metabolic synergy ?: ?O ka waikawa Butyric i hana ?ia e ho?āla i ka mea loa?a GPR109A, ho?oulu i ka ho?oka?awale ?ana o ke kelepona T, a ho?opa?a i ka helu helu kaulike o ka intestinal immune i ka 0.91 (palena olakino> 0.85).

Youdaoplaceholder0 Mokuna 2 Application Storm: Ho?oma?ama?a ?oko?a mai ka papa ?aina a hiki i kahi moe o ka Halemai ?

Youdaoplaceholder0 2.1 ?Oihana Mea?ai: ?O ka "Invisible Engine" me nā hana i ho?onui ?ia ?

Youdaoplaceholder0 Baking Revolution ? : Ua ho?omohala ka Hui Meiji o Iapana i nā kuki zero-sucrose ma o ka ho?ohana ?ana i ka hiki ke pa?a i ka wai (8.3g wai / g) a me ke kūpa?a wela (ka ho?omanawanui i ka 220 ° C) o ka polyglucose, e hō?emi ana i ka loli o ka glucose koko postprandial e 41%.

Youdaoplaceholder0 Beverage Innovation ? : Nongfu Spring's Intestinal Sparkling Water, ka mea i ho?ohana i ka colonic fermentation gas-producing property o polyglucose e ho?opau i ka constipation me ka ?ole o ka huhū, kū?ai ?ia ma luna o 8 miliona mau hue i kāna mahina mua ma ka mākeke;

Youdaoplaceholder0 Meal Replacement breakthrough ? : Ho?ohana ?o Soylent i ka US i kahi formula viscosity-gradient e ho?olō?ihi i ka manawa ho?oku?u lohi i 6 mau hola a ho?omaika?i i ka ho?omanawanui o nā mea holo marathon e 23%.

Youdaoplaceholder0 2.2 ?Ai ?ai kino: ?O ka "pale pale ?ōpū" no nā ma?i ma?i ICU

?O ka ha?awina RCT o Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University (n=204) e hō?ike ana:

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Youdaoplaceholder0 Ka pale ?ana i ka ma?i ? : I nā po?e ma?i ICU i ho?ohui ?ia me 15g o polydextrose i kēlā me kēia lā, ua ho?emi ?ia ka ma?i o ka enterogenous sepsis e 44%;

Youdaoplaceholder0 Mucosal repair ? : Plasma ligonin (kahi marker of intestinal permeability) i emi iho e 31% a me ka goblet cell density i ho?onui ?ia e 39%;

Youdaoplaceholder0 Immunomodulatory ? : Ua ho?onui ?ia ka nui o ka Serum IgA e 28%, a ua ho?i ka lakene CD4+/CD8+ T i ka pae ma?amau.

Youdaoplaceholder0 Mokuna 3 The Technological Revolution: Mai ka Molecular Design to AI-Enabled Precision Nutrition ?

Youdaoplaceholder0 3.1 Ho?ololi ho?ololi: Wehe i ka ho?opilikino ma ke koi ?

Youdaoplaceholder0 viscosity i mana?o ?ia : Ma ka ho?okomo ?ana i nā kaulahao ?ao?ao sorbitol, ua ho?omohala ?ia ka polyglucose disintegrating kiko?ī kiko?ī (?ano C), nona ka viscosity hā?ule loa i 10 mPa·s ma ka pH 7.0, kūikawā no ka po?e me ka constipation;

Youdaoplaceholder0 Mo?omeheu i ho?onui ?ia: Roguet, Farani, ho?omohala i ka ?enehana microcapsule Probiocoat? e ho?opili ana i nā probiotics i loko o kahi matrix polyglucose, e ho?onui ana i ka nui o ke ola o ka ?ōpū mai 15% a 92%.

Youdaoplaceholder0 3.2 Na?auao Mea Hana: Ho?opau i ke Code o ka hana pilikino ?

?O ka ?ōnaehana "Digital Twin of the Intestine" i kūkulu ?ia e NutriAI, he hui ?Isera?ela, e ho?ohui i 200,000 mau hihia o ka ?ikepili flora intestinal kanaka a me nā hi?ohi?ona ho?ohālikelike wai, hiki ke wānana i ka pane o ke kanaka i ka polydextrose:

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Youdaoplaceholder0 Dose optimization ? : ?O ka 8-12g / lā + fructooligosaccharide regimen hui pū ?ia i ?ōlelo ?ia no nā ma?i IBS i hō?emi i ka nui o ka distension o ka ?ōpū e 67%;

Youdaoplaceholder0 Scene fit ? : He ?ano ho?oikaika kino ki?eki?e i ho?ohālikelike ?ia no ka po?e ha?uki, e ho?onui ana i ka nui o ka fermentation colonic e 40% a pale i ka pilikia o ka ?ōpū i ka wā a?o.

Youdaoplaceholder0 \ n \ nMokuna ?Ehā: ?Aha ?Oihana: ?O ke kaua ?enehana ma nā mākeke Trillion-dollar ?

Youdaoplaceholder0 4.1 Hui Kūikawā: ?Ai ?ia nā hui Kina ma kahi pihi ?

Youdaoplaceholder0 Baolingbao Bio ? : E ho?olilo i 800 miliona yuan no ke kūkulu ?ana i ka waihona polyglucose nui loa o ka honua, ?enehana synthesis enzymatic e loa?a ai ka 99.9% ma?ema?e;

Youdaoplaceholder0 Hualixi Biotech ? : Ho?okumu ?ia ka polyglucose nano-fibrotic, ho?onui ?ia ka viscosity regulation sensitivity e 4 mau manawa, loa?a i ka NMPA Special Medical food approval;

Youdaoplaceholder0 Transnational layout ? : Ke hana pū nei ?o DuPont me ka Mayo Clinic e holomua i kahi ho?okolohua lapa?au Phase III o polydextrose i ka pale ?ana i ka ma?i ma?i colorectal.

?O Youdaoplaceholder0 4.2 Nā Lu?i Kognitive: ?O ka Gap mai ka Lab a i ka Mākeke Nui ?

?Oiai ua lawa nā hō?ike ?epekema, hō?ike ka noi?i mea kū?ai aku:

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Youdaoplaceholder0 ?Ike Makapō ? : ?O 31% wale nō o ka lehulehu e ho?omaopopo i nā ?oko?a hana ma waena o ka polydextrose a me nā fiber ma?amau;

Youdaoplaceholder0 Mana?o kuhi hewa ? : 45% o ka po?e kū?ai hewa i mana?o?i?o "?oi aku ka ?oi aku ka maika?i", hiki ke hō?eha ?ia e like me ka pu?u;

Youdaoplaceholder0 Industry Pane ? : Ua ho?oku?u ka Chinese Nutrition Society i ka Pepa Ke?oke?o ma ka noi ?ana o Polydextrose, e kau ana i kahi paepae palekana o 15g i kēlā me kēia lā.

Youdaoplaceholder0 Mokuna 5 Makana i ka wā e hiki mai ana: Ho?ololi hou i ka 'Smart Boundary' ?

Youdaoplaceholder0 5.1 Ho?omaka ?ia ?o Brain-Gut Axis Breakthrough: He Alahaka Molekala mai ka ?ōpū a i ka mana?o ?

Ua loa?a nā ho?okolohua holoholona hou loa ma California Institute of Technology:

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Youdaoplaceholder0 Ho?omaha hopohopo ? : ?O nā ?iole i loko o ka hui polyglucose intervention i ho?onui i ko lākou manawa ?imi i ka ho?ā?o maze e 53%;

Youdaoplaceholder0 Mechanism tracing ? : Butyric acid e ho?āla i ka hō?ike BDNF i ka hippocampus ma o ka pale koko-lolo, e ho?onui ana i ka synaptic density e 29%.

Youdaoplaceholder0 5.2 Synthetic Biology: 'O ke 'ano hope loa' o nā fiber programmed.

Ua ho?ololi ka hui ?o Ginkgo Bioworks ma ?Amelika Hui Pū ?Ia me ka ho?ohana ?ana i ka ?enehana CRISPR-Cas9 e hūnā pololei i ka "gene-encoded polydextrose" me nā hana ma?amau:

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Youdaoplaceholder0 Huli pono ? : Hiki iā ia ke ho?oulu i ka ulu ?ana o Achaemenia, a ua ho?onui ?ia kona nui e 80% i nā hi?ohi?ona obesity;

Youdaoplaceholder0 Pane akamai ? : ?O ka sensor pH i kūkulu ?ia, ho?omaika?i ?ia ka pololei o ka ho?ololi viscosity i ±5 mPa·s, i mana?o ?ia e komo i nā ho?okolohua lapa?au ma 2026.

Youdaoplaceholder0 Ka hopena: I ka hui ?ana o ka molecular Intelligence i Gut Ecology ?

?O ka huaka?i ?epekema o polydextrose kahi mo?olelo o ka ho?i ?ana mai kahi "huahana hana ?oihana" i kahi "intestinal ecological engineer". Hō?ike mai ia iā mākou ?o nā holomua maoli i ke olakino e ulu pinepine mai ka deconstruction hohonu a me ka ho?onohonoho hou ?ana o ke ?ano o ka mea. E like me ka ?ōlelo ?ana a ka mea lanakila Nobel ?o Jennifer Doudna, "Ke a?o nei ?o Synthetic biology iā mākou e hiki ke hā?awi ?ia i nā molekala me ka 'hiki ke no?ono?o'." I loko o kēia ho?ololi ?enehana o ke olakino ?ōpū, ?o ka polydextrose wale nō ke kumu ho?omaka - i ka wā e hui pū ai nā "molekole na?auao" i ke kaua, e loa?a i ke kanaka nā countermeasures pololei e kū?ē i nā ma?i ma?i.