Ma ke kahua o ka lā?au lapa?au, ?o ka Vitamin B13 (orotic acid) a me kāna mau derivatives ho?ohana nui loa, ?o ia iho he lā?au lapa?au maika?i no ka jaundice, ka ma?i ate, ka momona momona, ka ma?i hepatitis a me ka ma?i he hopena maika?i. Ma ka home a ma waho, ua ho?omohala ?ia i nā lā?au serialization orotic acid-based, e like me ka nitro acid whey, whey amino acids, a me nā mākeke ?o nā lā?au lapa?au maika?i loa he orotic acid me ka 5 - amino- imidazole-4 - A ma 90 °C amide pa?akai, ka pa?akai whey o ka ammonia -ethyl amide (Orazamide), hiki ke mālama ?ia me nā ?ano pharmacesis o nā ma?i. ?O ka hana hematopoietic, ka mea i lilo i ka mālama ?ana i nā ma?i ate ma waho o ka lā?au lapa?au mua me ka purine a ho?ohana ?ia e hāpai i ka ulu ?ana o nā keiki he hopena ho?olaha maika?i; kekahi orotic acid derivatives ma ka pu?uwai a he hopena ko?iko?i kekahi. ?O nā lā?au?awa?awa Whey no kona maika?i maika?i, nā hopena ?ao?ao, ?a?ohe ho?oulu ?ana o nā pu?upa?a, in vivo a me nā koena ha?aha?a a me ka hō?ili?ili i makemake ?ia a nānā. Kūkulu ?ia i nā makahiki i hala iho nei ua ho?omohala ?ia ka waikawa orotic no ka synthesis o nā waikawa nucleic, ?o ka nucleic acid ka mea nui o ke ola, no ka noi?i ?ana i ka biosynthesis protein a me nā genetics kanaka he ko?iko?i ko?iko?i, ua ho?omohala i kēia manawa i nā mea maka no kāna hana ?ana i nā mea?ai olakino nucleic a me nā lā?au lapa?au, hiki ke ho?opili a mālama i ka hana metabolic o nā ola he nui, e ho?opane?e i ka ?elemakule kanaka he hopena ko?iko?i.