Cov tshuaj formula ntawm spermidine yog C7H19N3, uas muaj ib pawg amine (NH) thiab ob pawg amino (NH2). Nws cov mis molecular yog qhia hauv qab no, teej tug mus rau lub pob tshab tsis muaj xim. Cov qauv tshuaj ntawm spermidine muaj peb lub nitrogen atoms, uas ua rau nws muaj qee yam tshuaj lom neeg thiab kev ua haujlwm lom neeg.

Spermidine muaj nyob rau hauv ntau yam khoom noj, tshwj xeeb tshaj yog nyob rau hauv ntau dua nyob rau hauv legumes (xws li taum mog), tag nrho cov nplej, fermented zaub mov (xws li cheese), nceb, thiab ib co txiv hmab txiv ntoo (xws li citrus txiv hmab txiv ntoo). Lub cev kuj synthesizes spermidine nws tus kheej, feem ntau nyob rau hauv daim siab, ob lub raum thiab cov hnyuv. Txawm li cas los xij, tus nqi ntawm cov spermidine tsim los ntawm tib neeg lub cev yog cuam tshuam los ntawm hnub nyoog, kev noj haus, plab hnyuv microbiota thiab caj ces, thiab tus nqi ntawm tib neeg lub cev synthesis pib poob qis tom qab hnub nyoog 30 xyoo, thiab qhov poob qis yog pom tseeb dua tom qab hnub nyoog 40 xyoo.

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Spermidine muaj cov tshuaj tiv thaiv oxidation (tshuaj dawb radicals), tiv thaiv kev laus (autophagy, ntxuav cov hlwb senescent), txhim kho kev laus (tshwj xeeb tshaj yog txhim kho zes qe menyuam, ua rau lub hnub nyoog laus) thiab tiv thaiv kab mob plawv thiab cerebrovascular, thiab lwm yam, tau dhau los ua cov khoom lag luam hnub qub hauv kev tiv thaiv kev laus.

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Spermidine muaj ob txheej txheem ntawm cov nroj tsuag extraction thiab lom fermentation, spermidine cov khoom nyob rau hauv lub khw yog tsuas yog muab rho tawm los ntawm mov los yog hom qoob mog raws li raw cov ntaub ntawv, thiab tus nqi ntawm 98% cov khoom ntshiab yog siab li 7000 yuan / kg.

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Biosynthesis: synthesizing spermidine nrog homoserine thiab putrescine (butylenediamine) ua substrate, dehydrogenating homoserine rau aspartate hemialdehyde thiab NADH nrog homoserine dehydrogenase, synthesizing aspartate hemialdehyde thiab putrescine rau carboxyglarine nrog NADH reenzyme rau hauv coenzyme thiab NADH. Thaum kawg, arginine decarboxylase decarboxylated arginine los tsim arginine. Qhov concentration ntawm spermidine hauv cov tshuaj tiv thaiv tuaj yeem yog li 13g / L.

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Tam sim no, domestic hluavtaws biology tuam txhab uas muag Huarui Biology, Zhongke Xinyang, Twinings Biology thiab Shanghai ergothione thiab lwm yam tuam txhab uas muag yog thawb hluavtaws biology spermidine khoom, leej twg nws thiaj li coj tus thawj coj nyob rau hauv industrialization thiab ua lub mainstream mov cia peb tos thiab saib.