0102 ib0304 ib05
Txoj kev npaj ntawm HMB-Ca
2025-03-17 IB
Txoj Kev 1:
Siv 4-methyl-4-hydroxy-2-pentanone (diacetone cawv) ua cov khoom siv tshuaj tiv thaiv, dej ua cov kuab tshuaj, NaOBr aqueous tov tau siv rau cov tshuaj tiv thaiv halogenated, ua raws li acidification thiab isobutanol extraction. HMB acid nyob rau hauv isobutanol extract yog ncaj qha salted nrog Ca (OH) 2 kom tau β - hydroxy - β - methylbutyrate calcium. Txoj kev no muaj qhov zoo ntawm cov khoom siab purity thiab qis ib puag ncig muaj kuab paug.
- Txoj Kev 2:1) Cov tshuaj tiv thaiv glacial acetic acid, sulfuric acid, thiab H2O2, ua raws li lub tshuab nqus tsev distillation, yields ib tug tov ntawm peracetic acid;
- 2) Sib tov cov khoom tau txais nyob rau hauv kauj ruam 1) nrog diacetone cawv, ntxiv methyl acetate raws li ib tug hnyav rau cov tshuaj tiv thaiv, thiab ces distilled thiab sau cov 70 ℃ feem. Cov residue tom qab distillation yog ib qho kev daws ntawm β - hydroxy - β - methylbutyric acid;
- 3) Ntxiv dej thiab sodium hydroxide tov rau cov distillation residue tau nyob rau hauv kauj ruam 2) kho pH rau 6.0-7.0. Tshav kub thiab yaj cov sib tov, ces lim nws. Ntxiv calcium chloride rau cov lim dej, do cov tshuaj tiv thaiv, thiab kho cov pH rau 6.5-7.0 dua kom precipitate β - hydroxy - β - methylbutyrate calcium. Lim thiab qhuav kom tau txais cov khoom