1. Qhov zoo ntawm cov yam ntxwv metabolic thiab tswj cov ntshav qabzib

1. Zero calories thiab tsis muaj metabolic residue
Tom qab cov qauv molecular ntawm sucralose tau hloov kho los ntawm chlorination, tib neeg lub plab zom mov tsis tuaj yeem decompose nws mus rau hauv cov suab thaj absorbable. Cov ntaub ntawv kho mob qhia tau hais tias li ntawm 85% yog tawm ncaj qha los ntawm txoj hnyuv tom qab noj, thiab 15% ntxiv yog metabolized los ntawm lub siab mus rau hauv cov tshuaj tsis muaj tshuaj lom thiab tawm hauv cov zis 13. Cov cuab yeej no ua rau nws muaj tseeb "zero calorie" qab zib, tsis muaj lub zog ntxiv rau cov neeg mob ntshav qab zib ntawm qhov koob tshuaj txhua hnub txog li 9mg / kg lub cev hnyav 28.

2. Ntshav qabzib stability mechanism
Tsis muaj insulin stimulation : Ib txoj kev tshawb fawb 2024 los ntawm International Diabetes Federation (IDF) qhia tias sucralose tsis ua kom lub qab zib saj receptor T1R2 / T1R3 hauv pancreatic beta hlwb thiab tsis ua rau insulin secretion 57.
Zam kev nqus cov piam thaj: Tsis zoo li sucrose, sucralose tsis cuam tshuam nrog kev ua haujlwm ntawm SGLT1 glucose transporter hauv cov hnyuv, thiab cov hnyuv nqus cov piam thaj hauv cov ntshav tau tswj hwm ntawm qib 36. Piv txwv li, 50 tus neeg mob ntshav qab zib hom 2 uas haus cov dej qab zib sucralose rau 30 hnub sib law liag muaj tsawg dua 0.3% hloov pauv hauv lawv qib A1c (HbA1c) 5.
Qhov thib ob, tus nqi tsim nyog ntawm kev tswj kev noj haus

1. Muaj peev xwm hloov cov suab thaj ib txwm muaj
Qhov qab zib ntawm sucralose yog 600 npaug ntawm sucrose, thiab tsuas yog ib qho me me tuaj yeem txaus siab rau qhov xav tau saj. Piv txwv li:

Ntxiv 30mg sucralose rau 300ml dej qab zib tsis muaj qab zib tuaj yeem ua tiav qhov qab zib sib npaug rau 10% sucrose tov 16;
Ntxiv 15mg rau txhua 100g ntawm cov hmoov nplej hauv cov khoom ci txo qhov kev noj sucrose li ntawm 45g 48.

2. Cov qauv kev noj haus optimization nyhuv
Txo cov carbohydrate dependence : Los ntawm kev hloov cov carbohydrates ib txwm, cov neeg mob ntshav qab zib tuaj yeem txo cov carbohydrates txhua hnub los ntawm 50-80g, sib npaug txiav 200-320kcal calories 27;
Txhim kho kev noj zaub mov kom zoo: Ua kom muaj kev noj qab haus huv ntawm cov ntshav qab zib ntau dua 40% los ntawm kev tso cai rau kev noj qab haus huv ntawm cov khoom noj qab zib xws li ice cream thiab ncuav mog qab zib 38.
Thib peb, kev zam ntawm kev pheej hmoo ntawm kev noj qab haus huv

1. Tiv thaiv kev mob ntshav qab zib
Txo qhov kev pheej hmoo ntawm cov kab mob hniav : Cov kab mob hauv qhov ncauj tsis tuaj yeem zom sucralose, thiab nws cov khoom tiv thaiv kab mob txo cov kab mob hauv qhov ncauj los ntawm 27% hauv cov neeg mob ntshav qab zib 46;
Tiv thaiv kab mob plawv: Tom qab hloov sucrose, cov neeg mob cov qib triglyceride txo qis los ntawm qhov nruab nrab ntawm 0.4mmol / L thiab cov lipoprotein tsawg-density (LDL) concentrations txo los ntawm 12% 78.

2. Adaptability rau cov xwm txheej tshwj xeeb
Kev ruaj ntseg kub kub: thaum ci qis dua 120 ℃, sucralose yuav tsis tsim cov khoom muaj kuab lom xws li chloropropanol, uas yog tsim rau kev ua cov ncuav qab zib tsawg 38;
Cov tshuaj sib xyaw ua ke: tsis muaj kev cuam tshuam nrog cov tshuaj hypoglycemic uas nquag siv xws li metformin thiab insulin, tab sis yuav tsum tau noj nrog cov tshuaj tiv thaiv coagulant xws li warfarin 27 ntawm 2 teev ib ntus.
Plaub, kev puas siab puas ntsws thiab kev sib raug zoo

1. Txhim kho lub neej zoo
Cov neeg mob ntshav qab zib muaj 62% txo qis hauv kev puas siab puas ntsws vim kev tsis txaus siab thiab qhov nruab nrab 3.2 taw tes txo qis hauv Kev Nyuaj Siab Scale (PHQ-9) tau qhab nia 68. Kev tshawb fawb 2024 Cov neeg siv khoom tau pom tias kev noj zaub mov txaus siab ntawm cov neeg mob ntshav qab zib uas siv sucralose ua cov piam thaj hloov tau nce ntawm 43% mus rau 79% 3.

2. Economic nqi optimization
Kev txo nqi kho mob: tuaj yeem txo tus nqi kho mob txhua xyoo ntawm tus mob ntshav qab zib ko taw, retinopathy thiab lwm yam teeb meem ntawm kwv yees li 3200 yuan / tus neeg 78;
Kev lag luam khoom noj khoom haus kev lag luam tshiab: Txhawb kev lag luam khoom noj tsis muaj qab zib kom loj hlob 18% txhua xyoo thiab xav tias yuav ncav cuag 120 billion yuan 14 hauv 2025.

5. Daim ntawv thov specifications thiab yav tom ntej prospects

1. Cov ntsiab cai ntawm kev siv scientific
Kev tswj koob tshuaj : Ua raws li WHO pom zoo txwv tsis pub tshaj 9mg / kg txhua hnub lub cev hnyav (kwv yees 540mg rau 60kg cov neeg laus) 28;
Cov txheej txheem xaiv : microencapsulation cov khoom siv thev naus laus zis tau nyiam los txo qhov cuam tshuam ntawm cov hnyuv (qhov txo qis ntawm bifidobacterium kev ua haujlwm tau txo los ntawm 30% mus rau 8%) 18.

2. Kev tsim kho tshuab kev taw qhia
Cov cuab yeej tswj xyuas qhov tseeb: Cov txheej txheem "qhia chlorination" tsim los ntawm Jinhe Kev Lag Luam hauv 2025 txo cov seem ntawm chloropropanol rau 0.01ppm 8;
Cov ntaub ntawv pov thawj-raws li kev tshawb fawb kho mob : International Diabetes Association tau tshaj tawm 100,000-tus neeg koom nrog kev tshawb fawb los soj ntsuam cov teebmeem ntev ntawm sucralose ntawm islet muaj nuj nqi 56.
xaus
Sucralose muab cov neeg mob ntshav qab zib nrog cov kev daws teeb meem uas sib npaug saj xav tau nrog kev tswj hwm kev noj qab haus huv. Nws cov txiaj ntsig tseem ceeb yog embodied hauv metabolic inertia, ntshav qabzib ruaj khov thiab tiv thaiv teeb meem. Nrog kev txhim kho cov txheej txheem tsim khoom (xws li microencapsulation technology) thiab txhim kho kev tswj hwm kev tswj hwm (xws li kev hloov kho ntawm Tuam Tshoj Cov Khoom Noj Khoom Noj Khoom Noj Khoom Noj Khoom Noj Hauv 2025), sucralose yuav dhau los ua cov cuab yeej muaj kev nyab xeeb thiab muaj txiaj ntsig zoo rau kev tswj hwm kev noj zaub mov zoo. Txawm li cas los xij, nws yuav tsum tau hais qhia tias kev hloov piam thaj tsis tuaj yeem hloov lub luag haujlwm tseem ceeb ntawm kev noj zaub mov kom zoo thiab kev tawm dag zog, thiab kev siv txuj ci yuav tsum yog raws li kev qhia kho mob ntawm tus kheej.