Ca HMB, tag nrho lub npe β-hydroxy-β-methylbutyrate calcium, yog ib qho ntawm cov khoom siv ntxiv ntawm HMB (β-hydroxy-β-methylbutyrate). Beta-hydroxy-beta-methylbutyric acid (HMB) yog dav pom nyob rau hauv citrus txiv hmab txiv ntoo thiab tej yam zaub xws li zaub paj, legumes xws li alfalfa, thiab tej ntses thiab nqaij nruab deg. β-hydroxy-β-methylbutyrate calcium (Ca HMB) yog calcium ntsev ntawm β-hydroxy-β-methylbutyrate (HMB). Vim yog qhov nquag nquag ntawm HMB, txhawm rau txhawm rau txhawm rau khaws cia thiab siv, nws feem ntau hloov mus rau hauv calcium ntsev thaum ua ke, thiab cov ntsiab lus tseem ceeb ntawm HMB yog li ntawm 77-82%.

HMB yog ib qho nruab nrab metabolite ntawm tib neeg qhov tseem ceeb amino acid leucine, thiab tib neeg lub cev tuaj yeem tsim tau me me ntawm HMB nws tus kheej. Hauv kev noj zaub mov ib txwm, tib neeg lub cev tsim tawm txog 300 txog 400 mg ib hnub, ntawm 90% yog los ntawm catabolism ntawm leucine. HMB tuaj yeem siv los txhawb cov leeg nqaij, txhim kho kev tiv thaiv kab mob, txo cov roj cholesterol thiab qis lipoprotein tsawg hauv lub cev kom txo tau qhov tshwm sim ntawm cov kab mob plawv thiab kab mob plawv, tab sis kuj tseem txhim kho lub cev muaj peev xwm kho nitrogen, tswj cov qib protein hauv lub cev, thiab tiv thaiv cov leeg nqaij hauv cov neeg mob pw tsaug zog lossis tuag tes tuag taw. Nyob rau hauv xyoo tas los no, vim hais tias nws tuaj yeem txo qhov kev puas tsuaj ntawm cov leeg nqaij tom qab kev tawm dag zog, kho cov nqaij fibers, ua kom cov leeg muaj zog thiab hlawv lub cev rog, nws tau dhau los ua cov khoom siv hnub qub hauv cov khoom noj khoom haus. Tsis tas li ntawd, HMB tau raug pov thawj hauv kev kho mob kom ceev qhov txhab kho thiab inhibit qhov mob. Cov kev tshawb fawb tau pom tias Ca HMB tuaj yeem ua kom muaj protein ntau thiab ua kom cov protein noj tsawg. Ca HMB ua ke nrog glutamine thiab arginine tuaj yeem txhim kho qhov tsis zoo nitrogen tshuav ntawm cov neeg mob thiab ua lub luag haujlwm zoo hauv kev rov qab los ntawm kev raug mob thiab kev phais.

Xyoo 2011, Tuam Tshoj tus qub Ministry of Health tau tshaj tawm kev pom zoo ntawm β-hydroxy-β-methylbutyrate calcium (Ca HMB) raws li cov khoom noj tshiab, kev siv cov khoom noj khoom haus kis las, kev siv tshuaj kho mob tshwj xeeb cov zaub mov, qhov pom zoo yog ≤3 grams / hnub. Xyoo 2017, National Health and Family Planning Commission tshaj tawm qhov nthuav dav ntawm daim ntawv thov ntawm Ca HMB los ntawm thawj ob daim ntawv thov mus rau cuaj, thiab tau tshaj tawm cov kev soj ntsuam kev pheej hmoo ntawm cov cuab yeej cuab tam los ua kev ntsuam xyuas kev nyab xeeb. Kev siv Ca HMB tau nthuav dav suav nrog cov dej haus, mis nyuj thiab khoom noj siv mis, cov khoom siv cocoa, cov khoom qab zib thiab cov khoom qab zib, khoom qab zib, cov khoom ci, thiab cov khoom noj tshwj xeeb, thiab cov nyiaj pom zoo tseem yog ≤3 g / hnub, uas tsis pub dhau qhov ntau npaum li cas ntawm cov neeg tuaj yeem pab dawb. Ca HMB tau lees paub tias yog GRAS los ntawm US Food and Drug Administration hauv xyoo 1995 thiab siv rau hauv cov khoom noj khoom haus kho mob thiab cov khoom noj tshwj xeeb. Hauv 20 xyoo dhau los, Ca HMB tau siv dav hauv cov khoom noj siv mis, cov khoom siv chocolate, dej haus, lub zog tuav thiab lwm yam khoom noj hauv Asmeskas kev lag luam. Ca HMB yog cov khoom noj khoom haus uas tau tso cai los ntawm Nyiv cov kev cai, uas tuaj yeem muab ntxiv rau hauv ntau qhov chaw xws li cov zaub mov zoo tib yam, cov khoom noj khoom haus kis las, zaub mov poob phaus, zaub mov zoo nkauj, thiab lwm yam. Rau cov tuam txhab lag luam thiab cov khw muag tshuaj, Ca HMB tam sim no yog ib qho ntawm cov khoom xyaw noj qab haus huv tshaj plaws ntawm cov khw muag khoom Nyij Pooj.

HMB tau siv dav hauv cov dej haus, thiab cov khoom zoo li no kuj muaj ntau nyob rau hauv kev ua lag luam thoob ntiaj teb. Piv txwv li, Juven launched los ntawm Abbott los txhawb protein synthesis, Myoplex Muscle Armor launched los ntawm EAS nyob rau hauv lub tebchaws United States, Fracora rau nruab nrab-hnub nyoog thiab cov neeg laus cov nqaij mob noj qab haus huv uas tsim los ntawm Concord nyob rau hauv Nyiv, thiab lwm yam, yog tag nrho raws li HMB raws li cov ntaub ntawv raw. Rau HMB kua dej haus, daim ntawv thov hauv tsev yog nyob rau theem pib, tab sis cov tuam txhab txawv teb chaws tau siv nws thiab tab tom ua haujlwm maj mam. Piv txwv li, kev ua si haus dej haus SUISPO launched los ntawm Japanese tuam txhab ISDG, thiab kev zoo nkauj qhov ncauj kua Flowage launched los ntawm Japanese Concord. Raws li cov khoom noj khoom haus tshiab uas tuaj yeem muab ntxiv rau cov dej haus, HMB tuaj yeem ua ke nrog ntau hom proteins, xws li whey protein concentrate, mis nyuj protein concentrate, whey protein cais, thiab zaub protein, thiab tseem tuaj yeem siv nrog cov vitamin thiab ntxhia formulations kom cov khoom ua haujlwm. Cov kua mis thiab mis nyuj hmoov nrog HMB tuaj yeem siv rau cov neeg laus hnub nyoog nruab nrab thiab cov neeg laus los pab tiv thaiv cov leeg nqaij, thiab tseem tuaj yeem siv rau cov neeg ncaws pob thiab qoj ib ce los muab cov leeg nqaij noj qab haus huv. Tsis tas li ntawd, qee qhov kev ua haujlwm yogurt nyob rau hauv kev ua lag luam, ntxiv HMB tuaj yeem hloov kho lub tswv yim ntawm cov khoom qub thiab muab lub tswv yim ntawm kev txo cov rog thiab cov duab shaping, thiab ntxiv cov khoom siv raw rau cov dej khov nab kuab kuj yog ib txoj hauv kev tshiab ntawm ntau lub teb chaws ice cream manufacturers. Ntxiv cov khoom xyaw HMB tuaj yeem ntxiv dag zog rau kev ua tau zoo ntawm cov dej khov nab kuab ntawm qhov chaw ua kom ntseeg tau qhov tsw thiab saj. Tsis tas li ntawd, HMB kuj tuaj yeem siv rau hauv cov khoom noj khoom haus thiab cov khoom qab zib, xws li cov khoom noj khoom haus nto moo tshaj plaws yog Maximuscle, uas ntxiv 20 grams protein, 3.4 grams creatine monohydrate thiab 1.6 grams HMB, uas tau tshaj tawm los txo cov protein ntau, tsim cov leeg thaum txhawb nqa kev rov qab ua haujlwm. Cov neeg tsim khoom noj rau kev poob rog tau siv sijhawm ntev HMB rau khoom qab zib, xws li Japanese tuam txhab ISDG tsimHMBkhoom qab zib, uas yog khoom qab zib rau cov neeg uas tsim cov leeg thiab poob rog.

Raws li kev noj zaub mov muaj txiaj ntsig zoo rau kev tiv thaiv thiab kev kho mob ntawm cov leeg nqaij pob txha,HMBtau raug lees paub los ntawm ntau cov kev tshawb fawb soj ntsuam, thiab HMB tau raug pov thawj hauv kev kho mob kom nrawm qhov txhab kho thiab inhibit qhov mob. Tam sim no, txoj kev loj hlob thiab kev siv ntawm HMB nyob rau hauv cov khoom noj khoom haus hauv tsev nyuam qhuav pib, tab sis nrog kev tshem tawm cov kev tswj hwm hauv tsev, nrog rau kev nce thiab kev txhawb nqa ntawm HMB ntau yam khoom noj khoom haus hauv lub ntiaj teb ua lag luam, nws ntseeg tias yav tom ntej, HMB yuav muaj kev nthuav dav dav hauv daim ntawv thov zaub mov.