Cov txheej txheem kev tsim cov tshuaj inositol yog lub siab hydrolysis. Vim muaj ntau xyoo dhau los ntawm kev tsim khoom, lub siab hydrolysis txoj kev yog lub ntsiab txheej txheem thev naus laus zis tau txais los ntawm cov tuam txhab tsim khoom hauv tsev thiab tau ua haujlwm tsis tu ncua hauv kev tsim khoom. Cov txheej txheem dav dav ntawm txoj kev siab hydrolysis yog raws li hauv qab no: phytin (hydrolysis) → hydrolysis tov (neutralization, filtration) → inositol tov (impurity tshem tawm thiab concentration, crystallization centrifugation) → crude inositol (solution thiab impurity tshem tawm, crystallization centrifugation). Ntawm lawv, hydrolysis thiab refining yog ob kauj ruam tseem ceeb.
Sodium phytate hydrolysis
Siv pob kws soaked dej ua raw khoom, sodium phytate yog tsim los ntawm ion exchange resin adsorption txoj kev, thiab ces raug rau siab hydrolysis cov tshuaj tiv thaiv los tsim inositol. Nyob rau tib lub sijhawm thaum tsim cov inositol, kev sib koom ua ke ntawm disodium hydrogen phosphate (kev tsim cov disodium hydrogen phosphate yog li 12 npaug ntawm inositol) tau txais txiaj ntsig zoo ntawm cov organic phosphorus los ntawm cov nplej, qhib txoj hauv kev tshiab rau kev rov qab los ntawm cov organic phosphorus hauv kev ua liaj ua teb thiab cov khoom lag luam sideline.
Cov txheej txheem ntau lawm: pob kws soaking dej yog adsorbed los ntawm ion txauv resin kom tau ib tug tej yam concentration ntawm sodium phytate tov, uas yog raug rau siab hydrolysis cov tshuaj tiv thaiv los tsim inositol thiab disodium hydrogen phosphate. Tom qab qee lub sijhawm cov tshuaj tiv thaiv, cov khoom raug tso tawm, lim, txias, thiab crystallized, ua rau nag lossis daus ntawm disodium hydrogen phosphate crystals. Cov tshuaj tiv thaiv hydrolysis ntawm sodium dihydrogen phosphate crystals yog ua kom zoo dua los ntawm anion thiab cation txauv resins kom txog rau thaum cov ntsiab lus ntawm anions thiab cations hauv cov tshuaj tiv thaiv hydrolysis ncav cuag tus qauv. Cov tshuaj refined hydrolysis cov tshuaj tiv thaiv tuaj yeem ua kom muaj zog thiab crystallized kom tau txais cov khoom tiav inositol. Cov txiaj ntsig ntawm inositol feem ntau cuam tshuam los ntawm peb yam: lub sij hawm hydrolysis cov tshuaj tiv thaiv, hydrolysis cov tshuaj tiv thaiv siab, thiab concentration ntawm sodium phytate tov. Los ntawm kev sim orthogonal, qhov pom kev zoo rau cov tshuaj tiv thaiv hydrolysis tau txais raws li hauv qab no: hydrolysis lub sij hawm ntawm 7-8 teev, concentration ntawm sodium phytate ntawm 20%, hydrolysis siab ntawm 1.5 MPa, thiab nruab nrab yield ntawm inositol li ntawm 0.1544% mus rau 0.1722%. Txhawm rau soj ntsuam cov txiaj ntsig zoo ntawm hydrolysis reactor, txaj thaiv hauv kev lag luam ion txauv ntauwd, kev hloov pauv peev xwm, thiab simulate cov kev ua haujlwm loj ntawm cov khoom siv hauv cov txheej txheem tsim khoom, kev sim ntsuas tau ua rau ntawm lub cuab yeej ua haujlwm ntawm 600m / a raws li cov xwm txheej saum toj no. Qhov nruab nrab cov txiaj ntsig ntawm inositol yog 0.1601% (ntau dua 2.5 npaug ntau dua li cov txheej txheem calcium phytate, thiab cov khoom lag luam zoo ua tau raws li ntau yam ntsuas tau teev tseg hauv National Pharmacopoeia), uas yog raws li cov ntaub ntawv ntsuas me me.
Atmospheric siab catalytic txoj kev
Cov txheej txheem atmospheric siab catalytic yog ib txoj kev tshiab rau kev tsim inositol uas tau tsim tshiab thiab muab tso rau hauv kev lag luam hauv Suav teb xyoo tas los. Nws hydrolysis thiab refining muaj cov yam ntxwv tshwj xeeb. Cov yam ntxwv tseem ceeb:
(1) Qhov tseem ceeb txo qhov kev nqis peev ib zaug hauv cov cuab yeej siv, thiab tuaj yeem txuag tau ntau dua 50% ntawm cov cuab yeej siv peev thaum qhov ntsuas tau zoo ib yam;
(2) Kev siv phytin hydrolysis catalyst shortens lub voj voog ntau lawm thiab txhim kho kev siv cov khoom raw;
(3) Cov txheej txheem refining tau raug txhim kho, ua rau muaj kev nce hauv cov khoom zoo thiab tawm los.
Atmospheric siab catalytic txheej txheem: Ib qho kev faib ua feem ntawm catalyst (muaj glycerol, urea, thiab calcium carbonate) yog ntxiv rau ib co concentration ntawm phytin tov ntawm atmospheric siab, thiab rhuab rau hydrolysis. Tom qab hydrolysis, pom, crystallization, ziab, thiab lwm yam txheej txheem, inositol tuaj yeem tau txais. Vim muaj cov yam ntxwv ntawm cov catalyst, inositol tuaj yeem crystallized hauv ib qho mus, ua rau cov khoom tiav zoo dua thiab ua kom cov txheej txheem yooj yim dua. Catalysts tuaj yeem siv tau.