Raws li thaum ntxov xyoo 1930s, cov kws tshawb fawb pom tau tias raug tshav ntuj lossis noj cov roj txiv roj, roj flaxseed, thiab lwm yam khoom noj uas muaj UV irradiated tuaj yeem tiv thaiv pob txha. Kev tshawb fawb ntxiv los ntawm cov kws tshawb fawb tau txheeb xyuas thiab npe hu ua vitamin D ua cov khoom muaj nyob hauv tib neeg lub cev rau kev sib ntaus sib tua osteoporosis.

Vitamin D (VD rau luv luv) yog ib tug rog soluble vitamin, uas yog ib pawg ntawm steroid derivatives nrog anti rickets los thiab cov qauv zoo sib xws. Qhov tseem ceeb tshaj plaws yog vitamin D3 (cholecalciferol, cholecalciferol) thiab vitamin D2 (calciferol). Vitamin D nyob rau hauv cov khoom noj tsuas yog los ntawm cov tsiaj raws li cov zaub mov xws li ntses siab, qe qe, butter, thiab lwm yam. Tom qab noj, nws yog absorbed los ntawm cov hnyuv me nyob rau hauv lub xub ntiag ntawm bile thiab thauj mus rau hauv cov hlab ntsha nyob rau hauv daim ntawv ntawm chylomicrons. Nws tau hloov mus rau hauv 1,25-dihydroxyvitamin D3 los ntawm daim siab, lub raum, thiab mitochondrial hydroxylase, uas muaj kev ua haujlwm lom neeg thiab tuaj yeem txhawb kev sib txuas ntawm calcium binding protein (CaBP) hauv plab hnyuv mucosa, txhawb kev nqus calcium, thiab txhawb cov pob txha calcification. 7-dehydrocholesterol, cholesterol derivative nyob rau hauv tib neeg lub cev, yog khaws cia subcutaneously thiab hloov mus rau hauv cholecalciferol nyob rau hauv tshav ntuj los yog ultraviolet hluav taws xob. Nws yog ib qho endogenous vitamin D uas txhawb kev nqus ntawm calcium thiab phosphorus.

VD yog derivative ntawm steroids. Nws yog dawb crystalline hmoov, soluble nyob rau hauv cov roj, muaj cov khoom ruaj khov, kub tsis kam, antioxidant, tsis tiv taus acid thiab alkali, thiab tuaj yeem rhuav tshem los ntawm fatty acid lwj. Tsiaj daim siab, ntses siab roj, thiab qe qe yog nplua nuj nyob rau hauv cov ntsiab lus. Qhov xav tau txhua hnub rau cov menyuam mos, menyuam yaus, cov hluas, cov poj niam cev xeeb tub, thiab cov niam laus yog 400 IU (cov chav nyob thoob ntiaj teb). Thaum tsis muaj, cov neeg laus muaj feem rau osteomalacia, thiab cov menyuam yaus ua rau rickets. Yog tias cov ntshav calcium txo qis, tej zaum yuav muaj tes thiab ko taw twitch, convulsions, thiab lwm yam, uas kuj muaj feem xyuam rau txoj kev loj hlob ntawm cov hniav. Kev noj cov vitamin D ntau dhau tuaj yeem ua rau cov ntshav calcium ntau, tsis qab los noj mov, ntuav, raws plab, thiab txawm tias ectopic ossification ntawm cov nqaij mos.