Poov xab beta-glucan yog ib qho ua haujlwm polysaccharide muab tau los ntawm cov phab ntsa ntawm tes ntawm cov poov xab. Xyoo 1941, Dr. Pillemer nrhiav tau ib yam khoom nyob rau hauv cov phab ntsa ntawm cov poov xab uas txhawb kev tiv thaiv kab mob. Xyoo 1961 Riggi tau txheeb xyuas cov khoom muaj nyob hauv cov poov xab glycan li beta-glucan [1]. Feem ntau qhov chaw ntawm beta-glucan kuj muaj xws li oats, fungi, seaweed, thiab lwm yam, vim hais tias lub cev tsis tuaj yeem tsim los yog zais cov beta-glucan nws tus kheej, nws yuav tsum tau ntxiv los ntawm lub ntiaj teb sab nraud.

Ntxiv rau β-glucan thiab cov poov xab cell phab ntsa kuj tseem muaj cov dej-soluble mannose thiab ib qho me me ntawm chitin, β-glucan suav txog 30% mus rau 60% ntawm qhov hnyav ntawm phab ntsa ntawm tes, nyob rau hauv cov txheej sab hauv ntawm phab ntsa ntawm tes, belongs rau cov txheej txheem polysaccharide, lub ntsiab ntawm lub cev ntawm lub cev muaj zog, yog li tswj lub cev muaj zog ntawm lub cev. physiological daim ntawv. Misaki et al. pom tias cov qauv ntawm cov poov xab β-glucan yog tsim los ntawm β-1, 3-bond, thiab muaj qee feem ntawm β-1, 6-bond residues.

Lub immunomodulatory kev ua tau zoo ntawm poov xab beta-glucan nyob ntawm nws lub hom phiaj meej, nws lub peev xwm los khi rau cov receptors tshwj xeeb ntawm lub cev tiv thaiv kab mob, thaum txhim kho phagocytosis ntawm macrophages. Cov txheej txheem no sai sai optimizes lub cev lub cev tiv thaiv kab mob thiab tswj kom pom qhov sib npaug ntawm lub cev tiv thaiv kab mob.

Beta-glucan ua feem ntau los ntawm kev khi rau peb hom beta-glucan receptor [4] : (1) Dectin-1 receptor; (2) CR3; (3) Lwm cov receptors, suav nrog cov scavenger receptor thiab LacCer. Thaum cov poov xab β-glucan nkag mus rau tib neeg lub cev thiab khi rau cov receptors, nws yuav ua rau kom cov phosphorylation ntawm nws cov intracellular immune receptor tyrosine motif (ITAM) thiab Syk, thiab qhib txoj kev PI3K / Akt, uas thaum kawg ua rau phagocytosis, microbial tso tawm cov kab mob txawv teb chaws thiab cytokine. cov kab mob txawv teb chaws. Thiab ces koj tau txais cov nyhuv ntawm kev tiv thaiv.

Cov txiaj ntsig kev noj qab haus huv ntawm daim tawv nqaij ntawm beta-glucan feem ntau tshwm sim hauv cov hauv qab no [6]:

1) Antioxidant muaj peev xwm: β-glucan muaj cov khoom siv antioxidant, uas tuaj yeem cuam tshuam cov tiam ntawm superoxides thiab lwm hom reactive oxygen (ROS) thiab txo qhov kev puas tsuaj ntawm oxidative kev nyuaj siab rau ntawm daim tawv nqaij.

2) Cov nyhuv moisturizing: Nrog nws qhov hnyav molecular, β-glucan muaj cov dej ruaj khov muaj peev xwm, uas tuaj yeem txuas cov dej molecules rau saum npoo ntawm daim tawv nqaij, tiv thaiv dej evaporation, thiab txo cov dej los ntawm epidermis (TEWL). Tsis tas li ntawd, nws tsim cov yeeb yaj kiab tiv thaiv ntawm daim tawv nqaij, pab tswj cov dej noo thiab softness ntawm daim tawv nqaij.

3) Kho tawv nqaij thiab kho muaj peev xwm: Seo et al. pom tias sib txawv ntawm beta-glucan tuaj yeem txhawb kev tsiv teb tsaws ntawm tib neeg keratinocytes (HaCaT) thiab tib neeg daim tawv nqaij fibroblasts (HDFa), thiab ua kom lub qhov txhab kaw thiab rov ua epithelialization hauv nas qauv [7]. Tsis tas li ntawd, cov tshuaj tiv thaiv kab mob thiab tshuaj tiv thaiv kab mob ntawm beta-glucan pab txo qhov mob thiab liab thiab soothe tawv nqaij. Ib txoj kev tshawb fawb nyob rau hauv Phau ntawv Journal of Therapeutic Dermatology qhia tau hais tias beta-glucan yog ib qho zoo ntxiv rau kev kho mob me me atopic dermatitis (eczema) [8].

4) Los tiv thaiv kev laus: Beta-glucan pab txo cov tsos mob ntawm daim tawv nqaij laus, xws li wrinkles thiab sagging. Nws txhawb cov synthesis ntawm collagen thiab lwm yam tawv nqaij extracellular matrix (ECM) Cheebtsam, ua rau lub thickness thiab elasticity ntawm daim tawv nqaij.

Tsis tas li ntawd, beta-glucan tseem muaj lub luag haujlwm ntawm kev tswj cov hnyuv, txo cov roj cholesterol, tiv thaiv qaug zog, pob txha noj qab haus huv thiab lwm yam.

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