Mannitol b? osmotic diuretic nke na-ad?gh? ar? ?r? nke ?ma na mmad? ma na-eme n'onwe ya, d? ka shuga ma ? b? mmanya shuga, na mkp?r? osisi na akw?kw? nri. Mannitol na-ebuli osmolality plasma ?bara, na-ebute mm?ba nke mmiri sitere na an? ah?, g?nyere ?b?r? na mmiri cerebrospinal, n'ime mmiri interstitial na plasma. N'ihi ya, ?b?r? ?b?r? edema, nr?gide intracranial d? elu, na ?b?r? cerebrospinal mmiri na nr?gide nwere ike ibelata. A p?kwara iji mannitol mee ihe maka ?kwalite diuresis tupu ?d?da ak?r? na-enwegh? ike gbanwee; nkwalite nke urinary excretion nke ihe na-egbu egbu; d? ka onye nn?chi anya Antiglaucoma; na d? ka ihe enyemaka gbasara ak?r? ?r?.