Ihe kar?r? nde mmad? 500 n'?wa niile nwere ?r?a shuga, 90% n'ime ha nwere ?d? ?r?a shuga 2. Nd? ?r?a kwes?r? ?ch?kwa mgbanwe shuga d? n'?bara maka nd?, yana shuga ?d?nala (d? ka sucrose na fructose) ka edep?tara d? ka ihe mgbochi nri n'ihi na ha na-ebute shuga shuga n'?bara ozugbo. Otú ? d?, ? na-esi ike ikpochap? ag?? ah? mmad? na-ach?si ike maka ?t? ?t?, na ngwaah?a nd? na-an?chi anya shuga malitere. Sucralose, d? ka onye na-at? ?t? ?gb? nke an?, ad?tala mmas? d? ukwuu maka njirimara "kalori efu na nnukwu ?t?" ya 13.

2. Njirimara metabolic na nchekwa nke sucralose
1. Metabolic uru
A na-agbanwe usoro ihe omimi nke sucralose site na chlorination, nke anagh? emebi site na enzymes digestive mmad?. Ihe d? ka 85% nke sucralose na-ap? ozugbo site na eriri af? mgbe ? ris?r? nri, 15% f?d?r?n? b? metabolized n'ime ogige nd? na-ad?gh? egbu egbu site na imeju wee p?ta na mmam?r?. Nnyocha ?l? ?gw? ekwenyela na nr?bama glycemic ya b? 0, na enwegh? njik? kp?mkwem na insulin secretion ?12. D?ka ?m?maat?, nnwale 2024 na-ach?kwa nke International Diabetes Federation (IDF) egosighi mgbanwe d? ?r?ba ama na glucose ?bara na-ebu ?n? na ?kwa A1C n'ime nd? ?r?a 50 nwere ?d? ?r?a shuga 2 nke riri ihe ????? sucralose maka ?b?ch? 30 n'usoro.

2. Nyocha dialectical nke esemokwu nchekwa
? b? ezie na nch?p?ta b? isi na-akwado nchekwa ya, a ka nwere nchegbu gbasara ihe egwu nd? nwere ike ime:

Mmet?ta microbiota : Nnyocha 2024 nke e bip?tara na Nature Microbiology gosiri na oriri kwa ?b?ch? kar?a 15g nke sucralose na-egbochi ?r? nke probiotics d? ka bifidobacterium, na-ebute mbelata 20%-30% na gut microbiota diversity ?37;
Mmek?r?ta ?gw? ?j??: Mgbe ejik?tara ya na anticoagulant warfarin, sucralose nwere ike belata bioavailability ?gw? site na 12%-15%. 27 kwes?r? iwere awa 2 iche;
;
nhazi ihe ize nd? nke ngwaah?a: nnukwu mmiri ?k? (> 150 ℃) nwere ike ?mep?ta ?n??g? chloropropanol (Nke at?, usoro sayens? nke nn?chi shuga
1. A na-emeghar? usoro onunu ogwu ka ? b?r? ebe ah?
òtù Ah? Ike ?wa (WHO) na-at? aro ka nd? nwere ?r?a shuga na-eri ihe kar?r? 9mg/kg nke sucralose kwa ?b?ch? (ihe d? ka 540mg maka okenye 60kg). ? d? mkpa ka ekewap?ta ?n?d? n'ime ngwa bara uru:

ihe ????? na-esi ísì ?t?: ihe ????? 300ml nwere ihe d?ka 30mg sucralose, nke b? naan? 5.5% nke oke nchekwa 16;
Ngwongwo esiri esi : H?r? pastry mere site na usoro okpom?k? d? ala (2. njikwa nri jik?tara ?n?
Ihe nn?chi shuga ab?gh? ihe dochie anya njikwa shuga n'ozuzu:

Nri oriri na-edozi ah? : Gwak?ta ?ka dum (GI n'okpuru 55) na eriri nri (25-30g kwa ?b?ch?) iji gbuo oge nnabata glucose ?46;
Nleba anya glucose ?bara: Ach?p?tara glucose ?bara ka awa 2 gachara iri nri dochie shuga, wee guzobe ebe nchekwa nzaghachi nke onwe 58.
4. Usoro ?l? ?r? na ag?makw?kw? nd? ah?a
1. Standardization nke nri labeling
?d? edeghar?ghar? nke iwu izugbe nke China maka akara ngosi nri akwadoro na 2025 ch?r? ka nri nwere sucralose kwes?r? ka ejiri ?d? aka ná nt? "Nd? ?r?a na-ar?a ?r?a shuga kwes?r? ?ch?kwa mkpok?ta carbohydrate oriri" ma gosip?ta ?d?naya mgbakwunye (mg/100g) ?24.

2. nzaghachi ?gba aghara ah?a
Na 2024, General Administration of Market Supervision ch?p?tara na 18.7% nke “enwegh? shuga” na-echekwa glucose agbakwunyere n'ezie, na-egosi d? ka sucralose. Nd? ah?a kwes?r? ?h?r? ngwaah?a nwere asambodo SC yana ak?k? nnwale zuru oke ?78.

5. Ntuziaka mmepe n'?d?nihu
1. Nkà na ?z? ?h?r?
N'af? 2025, Jinhe Industrial weputara usoro "chlorination nt?z?aka" iji belata ihe f?d?r? nke sucralose chloropropanol ruo 0.01ppm, wee gbasaa oge nt?hap? eriri af? site na tekn?z? microcapsule iji belata ?gba aghara nje 18.

2. Nch?p?ta ah?ike dabere na akaebe
International Diabetes Association ewep?tala mmemme nleba anya nke af? 5 "dochie shuga na ?r?a metabolic syndrome" iji nyochaa nchekwa ogologo oge nke sucralose na 100,000 nd? nwere ?r?a shuga.