Youdaoplaceholder0 1.1 Ime Anwansi an? ah? nke viscosity gradient: Mgbanwe ugboro at? site na af? gaa na colon

?d?d? molek?la nke polyglucose b? ihe mkpofu glucose nwere njik? na-enwegh? usoro, yana nkwek? a p?r? iche na-enye ya ihe p?r? iche rheological. Na gburugburu acidic nke af? (pH 1.5-3.5), ?d? molek?la ya na-etolite ngwa ngwa usoro netw?k? nwere ak?k? at? site na agb? hydrogen, viscosity na-abawanye ozugbo ruo 1200 mPa·s (ihe d? ka okpukpu ab?? nke mman? a??), na-egbu oge nke mkpofu af? nke ?ma site na 40% ma na-agbat?kwu mmet?ta. Mgbe ? banyere n'ime obere eriri af?, ka uru pH na-ebili na 6.0-7.5, ?f?d? njik? hydrogen na-agbaji na viscosity na-adaba na 300-500 mPa·s. ? nagh? egbochi oke nnabata nke nri ma ? b? jik?ta ya na bile acid iji belata ?n?ego nnabata nke cholesterol. Mgbe ? na-erute eriri af?, n'okpuru ?r? nke microbial fermentation, viscosity na-agbada n'okpuru 50 mPa·s, na-ahap? acid fatty acid d? mkp?mkp? (SCFAs) iji nye ike maka probiotics (Njirimara 1).

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Nkwado data Youdaoplaceholder0:

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?n??g? mkpochap? af? na-egbu oge: 40% (Nri Hydrocolloids 2022, n=30)

?n?ego mgbochi nnabata cholesterol: 22% (data asambodo GRAS sitere na US FDA)

Mm?ba mmep?ta SCFAs: mkpok?ta acetic acid colonic m?bara ugboro 3.8 (Gut 2023, Model Animal)

Youdaoplaceholder0 1.2 at?mat? "nri nke ?ma" maka microbiome ?

Usoro viscosity nke polydextrose ab?gh? naan? na-emet?ta usoro mgbaze an? ah?, kamakwa na-emek?r?ta mmek?r?ta siri ike na ah?h?a intestinal. ?n?d? viscosity d? elu na-etolite ihe mgbochi an? ah? na eriri af? d? nso, na-ebelata k?ntakt? n'etiti nje bacteria na mucosa eriri af?. Ka viscosity na-ebelata, ? na-eji nway?? nway?? na-agbanwe gh?? mkp?r? na-agba agba, na-akpali mmas? na mm?ba nke Bifidobacteria na nje bacteria lactic acid. Otu otu sitere na Mahadum Cambridge ch?p?tara site na usoro metagenomic na oriri na-aga n'ihu nke 12g / ?b?ch? polydextrose maka izu 8 nwere ike ?kwalite ogo F/B nke Thick-miliae/Bacteroidites na 1.3 (ya na usoro ah?ike d? mma nke 1.5-2.0), yana ?bawanye ?ba nke butyric acid bacteria (d? ka Fac 8%). Mmet?ta nke ab?? a nke "nchekwa mb?, mgbe ah? nri" na-egbo mkpa gburugburu ebe obibi nke ak?k? d? iche iche nke eriri af?.

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Onye nwe obodo0 Isi nke 2 Ngwa mgbanwe mgbanwe ndap?ta: Ntinye n'oke ala site na nri ejiri shuga ruo na nri ICU ?

Youdaoplaceholder0 2.1 Industryl? ?r? nri: “?kp?kp? a na-ad?gh? ah? anya” nke ngwaah?a GI d? ala

N'ebe a na-eme ach?cha, ikike ijide mmiri d? elu (> 8g mmiri / g) na nkw?si ike nke okpom?k? (nnweta ruo 200 ℃) nke polyglucose na-eme ka ? b?r? ezigbo nn?chi maka sucrose. Kuki "Zero Sugar Cookies" nke Meiji Group nke Japan kwalitere na-eji polyglucose d? ka isi eriri, na-enweta nan? 1.2g nke carbohydrates net kwa kuki, na udidi na crispness ad?gh? iche na nke ngwaah?a nd? nwere shuga. Nke kachas? mkpa, ?kp?r? viscosity ya na eriri af? nwere ike igbu oge nnabata glucose ma belata ?n? ?g?g? glucose ?bara mgbe nri gas?r? site na 34% (data ah?ike sitere na nlek?ta ?r?a shuga 2021).

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Youdaoplaceholder0 Innovative case:

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Youdaoplaceholder0 Nestle : The "Smart slow-release energy bar" nke mep?tara site na ?gwak?ta polydextrose na dextrin na-eguzogide ?gw? na-egosip?ta njiri gradient viscosity nke na-agbat? absorption carbohydrate ruo awa 6, na-egbo mkpa ike na-aga n'ihu nke nd? na-agba ?s? marathon.

Youdaoplaceholder0 Nongfu Spring : Ewep?tara "Mmiri Intestinal Vitality Sparkling Water" yana polyglucose agbakwunyere, nke na-eji ihe nf?kas? viscosity ya d? ala na-emep?ta gas d? nro na eriri af? iji kpalite peristalsis eriri af?. O rere ihe kar?r? otu nar? nde karama n'ime ?nwa at?.

Youdaoplaceholder0 2.2 Nri ah?ike: "Nchekwa mgbochi intestinal" maka nd? ?r?a ICU ?

Ihe mgbochi mucosal intestinal na nd? ?r?a na-ar?a ?r?a siri ike na-ebutekar? ?r?a usoro. Nnwale a na-ach?kwa nke enwegh? usoro (n = 158) nke ?l? ?gw? Njik? Mb? nke Mahadum Zhejiang mere gosip?tara na nd? ?r?a ICU b? nd? agbakwunyere na 15g nke polyglucose kwa ?b?ch? nwere mbelata 42% na njedebe nke endotoxemia na mbelata 29% na ntinye aka nke eriri af? (plasma ligonin). Usoro ah? d? na steeti viscosity d? elu na-emep?ta ihe nkiri nchebe n'ime af?, na-ebelata ihe ize nd? nke ?nya na-akpata nchekas?. Acid butyric nke ak?k? colonic wep?tara na-akwalite ozugbo mm?k? nke oyi akwa mucus (na-abawanye ?n? ?g?g? mkp?r? nd? goblet site na 37%), na-enweta nkwado nke mgbochi an? ah? na nke kem?kal.

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Onye nwe ebe obibi0 Isi nke 3 Mmepe nka na ?z?: nkwalite sitere na 'Formulas' p?tara' gaa na' Nri Nri' Mgbak? '

Youdaoplaceholder0 3.1 Usoro ngbanwe nke molikula

Ogologo nzaghachi viscosity nke polydextrose ?d?nala nwere oke, na-eme ka o sie ike ?kwado nke ?ma ihe ach?r? n'otu n'otu. Na June 2023, DSM nke Netherlands kwup?tara tekn?z? ikike ikike ya "PolySmart ?", nke mep?tara ?d? viscosity at? d? iche iche site na ?ch?kwa ogo polymerization (?n?ah?a DP) nke glucose na sorbitol:

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Youdaoplaceholder0 G ?d? ? (mmelite af?): Viscosity ruru 1500 mPa·s na pH

Youdaoplaceholder0 C ?d? ? (colon-ezubere iche): Viscosity na-adaba nke ?ma ruo 30 mPa·s na pH> 6.5, h??r? maka nd? nwere af? ntachi;

Youdaoplaceholder0 Type B (?n?d? kw? ?t?): Mgbanwe d? nro nke mkpok?ta viscosity eriri af?, dabara maka njikwa glucose ?bara na nd? ?r?a nwere ?r?a shuga.

Youdaoplaceholder0 3.2 AI-enyere aka imewe nhazi

Ikpo okwu "FiberEngine" nke ?l? ?r? Israel NutriAI mep?tara na-ejik?ta data 2 nde gut microbiota na ?d? mgbanwe mmiri, nke nwere ike ?k? am?ma mgbakwunye kachas? mma nke polydextrose n'okpuru af? d? iche iche na ?n?d? ?r?a. D?ka ?m?maat?, maka nd? ?r?a nwere IBS (?r?a obi mgbakas? ah?), usoro ah? na-at? aro ngwak?ta kwa ?b?ch? nke 8-10g nke polyglucose na 2g nke fructooligosaccharides, nke na-ebelata ?gbaghara nke af? site na 65% (data njirimara onye ?r? 2023).

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Youdaoplaceholder0 Isi nke 4 ?gba aghara ?l? ?r?: "Fiber Blue Ocean" nke nd? dike na-agba mb? maka ?

Youdaoplaceholder0 4.1 ?s? ikike na-ekpo ?k?

Ah?a polydextrose zuru ?wa ?n? na-at? anya na ? ga-eto site na nde dollar 870 na 2023 ruo 2.1 ijeri US dollar na 2030 (CAGR 12.3%). China agh?wo isi agha.

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Youdaoplaceholder0 Baolingbao Bio : Tinye ego 500 nde yuan iji gbasaa ah?r? mmep?ta 30,000 kwa af?, na-eji usoro njik? enzymatic iji nweta 99.5% ?d? ?cha;

Youdaoplaceholder0 Rogate : Probiotic-polyglucose microcapsules mep?tara na mmekorita ya na CHR. Hansen m?bara ?n? ?g?g? nlanar? na-eguzogide acid ruo 90%;

Youdaoplaceholder0 Matsuya Chemie, Japan : Ewebatara "nano-fibrotic polyglucose," nke nwere ikike ?ch?kwa viscosity ugboro at? ma FDA enyela ya aha ?gw? mgbei maka ?r?a af? af? d? mkp?mkp?.

Youdaoplaceholder0 4.2 Ihe ?ma aka ab?? nke ?kp?r? na ngh?ta

? b? ezie na akwadoro polydextrose d? ka eriri nri site na European Union, China na mba nd? ?z?, nd? na-az? ah?a ka nwere ngh?tahie. Nnyocha sitere na FMCG na United States na-egosi na ? b? naan? 28% nke nd? na-az? ah?a nwere ike ?mata ?d?iche d? n'etiti polydextrose na starch na-eguzogide ?gw?. Nke ka nj?, oke oriri (> 50g / ?b?ch?) nwere ike ibute mgbaka af? ma ? b? gbochie nnabata ?nweta. ?l? ?r? ah? ch?r? ngwa ngwa guzobe ?kp?r? usoro onunu ogwu ahaziri ahazi.

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Onye nwe ebe obibi0 Isi nke 5 Na-ele anya n'ihu: "Fiber Network" sitere na GUT gaa na ah?ike an? ah? ?

Youdaoplaceholder0 5.1 Ihe akaebe ?h?r? maka nhazi nke ?b?r?-gut axis

Na mbido 2024, Institutel? ?r? Nkà na ?z? California ch?p?tara na nnwale òké na butyric acid mep?tara site na gbaa ?ka nke polydextrose nwere ike kpalite neurons hypothalamic site na akwara vagus, na-ebelata omume nd? yiri nchekas? site na 43%. Nke a na-enye nk?wa ?kwa nke mkp?r? nd? ihe nketa maka nkwup?ta ah? na "nri nwere nnukwu eriri na-eme ka ah?ike uche d?kwuo mma".

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Youdaoplaceholder0 5.2 Ihe ohuru na-emebi emebi na bayoloji s?ntetik

Zymergen mmalite US ejirila tekn?z? CRISPR gbanwee Trichia pastoris, na-enyere ya aka zoo "polyglucose emezighar?r?" ozugbo site na iji usoro viscosity ahaziri iche. Ngwaah?a a gosip?tara mm?ba 80% na nzaghachi pH ziri ezi na nnwale mgbari mgbaze ma na-at? anya ?banye na ?kwa nnwale ?l? ?gw? na 2025.

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Youdaoplaceholder0 Mmechi: Na-ak?wap?ta "oke ?g?g? isi" nke Fiber ?

Mmet?ta gradient viscosity nke polydextrose na-egosi oge ?h?r? maka eriri nri, na-esi na "mgbakwunye na-agafe agafe" gaa na "usoro iwu na-ar? ?r?". Mgbe ak?k? eriri nwere ike ?hazighar? ?r? ya n'onwe ya na nzaghachi na gburugburu ebe nri nri, any? nwere ike na-ah? mgbanwe mgbanwe na sayens? nri - mmemme ah?ike n'?d?nihu agagh? ab? mb? naan? otu molecule, kama ? b? ?gba egwu nke ihe smart, microbiome, na ?g?g? isi. D? ka onye nwetara ihe nrite Nobel na Chemistry, Frances Arnold kwuru otu oge, "Mkp?r? nd? nd? d? n'okike enweelar? ohere na-enwegh? njedebe. Ihe any? kwes?r? ime b? ?m?ta ige nt? 'as?s? nke oge na ohere' ha."