N'af? nd? na-ad?begh? anya, na ?n? ?g?g? oke ibu zuru ?wa ?n? na-ar? elu yana usoro nke ?r?a shuga na-emet?ta nd? na-eto eto na-akawanye nj?, "?ch?kwa shuga ?bara" agh?wo isi okwu na ah?ike ?ha. N'?g? a megide ?t? ?t?, as?mpi d? n'etiti sucrose ?d?nala na ihe nn?chi shuga d? n'ime sucralose na-akawanye nj? - nke mb? na-an?chite anya ?t? mb? sitere n'okike nyere, ebe nke ikpeaz? na-egosip?ta ?ch?ch? nkà na ?z? nke mmad? iji gbanwee mkp?r? nd?. As?mpi ha ab?gh? naan? egwuregwu ?t?, kamakwa na-egosip?ta mgba ike siri ike n'etiti nchekwa nri, sayens? metabolic na ?d?mma az?mah?a.

Onye nwe ebe obibi0 Isi nke 1 Mgbanwe d? ?t?: Nt?le tekn?z? sitere n'ubi okpete gaa na ?l? nyocha.

Youdaoplaceholder0 1.1 Sucrose: Koodu ?t? nke okike

Enwere ike ?ch?ta ak?k? ihe mere eme nke sucrose na India n'ihe d? ka 500 BC, mgbe ?m? mmad? bu ?z? wep?ta sugar crystalline site na ihe ????? okpete. ?d?d? kem?kal ya b? usoro disaccharide nke glucose na fructose (C??H?O?), d? ka ngwaah?a nke photosynthesis na osisi, na-enye ike ngwa ngwa maka mmad?.

Youdaoplaceholder0 Mmep?ta mgbagha ? : okpete/ sugar beet ?p? → ?d? ?cha → crystallization, dabere na ihe ?k?k? ugbo na nhazi an? ah?;

Youdaoplaceholder0 Isi uru: calorie 4 kwa gram, akara ?t? nke 1, dabara na nd? na-anabata uto uto;

Youdaoplaceholder0 mkpa omenala: Site na "?la edo" nke Rome oge ochie ruo na mkp?r? obi na-eme ach?cha ?gbara ?h?r?, okpete na-ebu ?ch?ch? ebump?ta ?wa mmad? maka ?t?.

Onye njide ebe obibi0 1.2 Sucralose: Ihe ?t?nanya d? ?t? gbanwere nke molekul

N'af? 1976, nd? ?kà mm?ta sayens? na Tate & Lyle d? na UK, mgbe ha na-emep?ta ?gw? ah?h?, ch?p?tara na mberede na-edochi otu hydroxyl at? d? na sucrose molecule na chlorine atom (C??H??Cl?O?) ab?gh? ah? mmad? na-at? ?t? nke ukwuu. Nch?p?ta a welitere Sucralose, na-ebute oge ?h?r? maka ?l? ?r? nn?chi shuga.

Youdaoplaceholder0 Mmep?ta mgbagha ? : Sucrose chlorination → chemical mgbanwe → ?d? ?cha, dabere na nkenke kem?kal? njik?;

Youdaoplaceholder0 Performance breakthrough : 600 ugboro ?t? kar?a sucrose, efu kalori, okpom?k? na-eguzogide (dabara maka ach?cha na igba ogwu nke ihe ?????);

Youdaoplaceholder0 ?ganihu az?mah?a: Mgbe FDA kwadoro ya na 1998, sucralose weghaara ah?a ihe ????? na-enwegh? shuga, yana ?n? ah?a ah?a zuru ?wa ?n? kar?r? ijeri $ 1.8 na 2022.

Onye nwe ebe obibi0 Isi nke 2 Esemokwu Ah?ike: Usoro metabolic na oke nchekwa

Youdaoplaceholder0 2.1 Mmet?ta mma agha ihu ab?? nke sucrose

Youdaoplaceholder0 Metabolic pathway ? : Sucrose → gbajiri n'ime eriri af? banye glucose + fructose → na-abanye n'?bara maka inye ike ma ? b? chekwaa ya ka ab?ba.

Youdaoplaceholder0 Ihe akaebe na-akwado : WHO na-at? aro ka oriri shuga n'efu kwa ?b?ch? na-erugh? 10% nke mkpok?ta calorie (ihe d?ka gram 50 nke sucrose);

Youdaoplaceholder0 ?d? aka ná nt? ihe ize nd?: Ejik?tara oke oriri na oke ibu, caries eze, nguzogide insulin, na ?nw? nde 35 site na ?r?a shuga n'?wa niile kwa af?.

Youdaoplaceholder0 2.2 Ihe mgbagwoju anya nchekwa nke sucralose

Youdaoplaceholder0 Njirimara metabolic : molecule ah? buru ibu nke ukwuu nke a na-agbaji ya site na intestinal enzymes → a na-ewep? ya ozugbo na ? nagh? etinye aka na metabolism ume.

Youdaoplaceholder0 nkwado nd? ?r? : FDA, EFSA na JECFA ekpebiela nchekwa ya, yana oriri a na-anabata kwa ?b?ch? (ADI) nke 5mg/kg ar? ah?;

Youdaoplaceholder0 Mgbado anya nke esemokwu:

Youdaoplaceholder0 Gut microbiota disturbances : Nnyocha 2018 na Nature t?r? aro na sucralose nwere ike igbochi uto nke probiotics ma ? b? mee ka nsogbu metabolic d?kwuo nj?;

Youdaoplaceholder0 Ihe ize nd? nke ire ere d? elu: Chloropropanol (ihe nwere ike ibute ?r?a carcinogen) nwere ike hap? ya kar?a 120 Celsius C, mana mmep?ta n'ezie na isi nri d? oke ala;

Youdaoplaceholder0 Echiche ?dabere na ?t? uto: Iri ma ? b? na-eme ka ag?? maka nri d? ?t? d? ogologo ogologo oge na-abawanye oriri calorie na-ap?tachagh? ìhè.

Youdaoplaceholder0 echiche ?kachamara:

Nd? na-at? ?t? artificial ab?gh? ihe efu maka nsogbu ah?ike, mana ha ab?gh?kwa panacea. Isi ihe b? ?gh?ta ?n?d? ndap?ta ya.

- Dr. Sara Smith, Pr?fes? nke Nutrition na Mahadum Johns Hopkins

Youdaoplaceholder0 Isi nke 3 Ngosip?ta ngwa: ?gb? agha d? ?t? nke ?l? ?r? nri

Youdaoplaceholder0 3.1 enwegh? ike dochie sucrose

Youdaoplaceholder0 Ogige ?sa ach?cha: mmeghachi omume caramelization ( mmeghachi omume Maillard) na-enye ach?cha ach?cha ?la edo na-esi ísì ?t?. Sucralose enwegh? njirimara nd? a na agba agba na ekpomeekpo kwes?r? ?gbakwunye;

Youdaoplaceholder0 ?l? ?r? ihe ?????: Colas omenala na-adabere na ?t? d? ar? nke sucrose. Nnwale kpuru ìsì site n'aka nd? na-az? ah?a na-egosi na a na-akat?kar? ns?ghar? nd? dochie shuga maka inwe "ihe ?t? na-ad?gh? ike";

Youdaoplaceholder0 omume na-ap?ta : nri ejiri aka mee elu na-ekwusi ike iji sucrose eke ma mesie echiche nke "Label d? ?cha".

Youdaoplaceholder0 3.2 alaeze az?mah?a nke sucralose

Youdaoplaceholder0 Ihe ????? na-enwegh? shuga : ?d? d? ka Coke Zero na Yanki Forest enwetala "ak?k? ifo-calorie" na sucralose, na ah?a ihe ????? na-enwegh? shuga na China toro site na 25% na 2023;

Youdaoplaceholder0 Nri na-ar? ?r? ? : D? ka isi ihe ?t? na nri p?r? iche maka ?r?a shuga na nri nn?chi kalori iji lebara esemokwu d? n'etiti ?t? na calorie;

Youdaoplaceholder0 Invisible penetration : N'ubi nd? na-ab?gh? nri d? ka ntacha eze na mkpuchi ?gw?, na-eji ohere mgbochi caries na nkw?si ike ya.

Youdaoplaceholder0 Case: At?mat? ?t? Pepsi-Cola

Na 2021, PepsiCo kwup?tara na ? ga-akw?s? aspartame n'ah?a North America wee gbanwee kpamkpam na usoro sucralose. Mkpebi a butere mm?ba 14% n'ah?a ah?a nke ah?r? ngwaah?a na-enwegh? shuga kwa af?, na-akwado mmas? nd? ah?a maka "ihe nn?chi shuga d? mma".

Youdaoplaceholder0 Isi nke 4 Echiche ?d?nihu: Mgbanwe na ?d? n'otu nke ihe ?t?.

Youdaoplaceholder0 4.1 Tekn?z? Ntughar?: Mbili nke ihe ?t? ?gb? nke at?

Youdaoplaceholder0 Natural sugar nn?chi : Stevia na mogroside na-ejiri akara "osisi wep?" na-ejide ah?a d? elu;

Youdaoplaceholder0 At?mat? ngwak?ta : Ngwak?ta ngwaah?a nke sucralose na erythritol, na-edozi uto na uru ah?ike;

Youdaoplaceholder0 Precision ?t? ?t?: AI-enyere aka imewe nke mkp?r? nd? ?t? ?t? ?h?r? na-e?omi ?z? metabolic na uto nke sucrose.

Youdaoplaceholder0 4.2 nkwalite nke nd? na-az? ah?a cognition

Youdaoplaceholder0 Scientific sugar Control School ? : H?r? sweeteners d? ka ?n?d? - sucrose maka mgbe mmega ah? sugar replenishment, artificial sweeteners maka kwa ?b?ch?;

Youdaoplaceholder0 Natural fundamentalism ? ? guzogide ihe mgbakwunye mmad? niile iji kwalite oriri nke sucrose organic;

Youdaoplaceholder0 Gen Z esemokwu: 87% nke nd? na-eto eto na-az?ta ihe ????? na-enwegh? shuga ma na-eri nri d? elu d? ka tii mmiri ara ehi, na-egosip?ta esemokwu d? n'etiti mmata ah?ike na ihe ?t?.

Youdaoplaceholder0 Mmechi: Isi ihe d? ?t? b? nh?r?

Na egwuregwu a d? n'etiti ?d?d? na artificiality, ? d?gh? onye mmeri zuru oke. Sucrose na-an?chite anya nkwek?r?ta mb? d? n'etiti mmad? na okike, na sucralose na-egosip?ta ?ch?ch? nke nkà na ?z? iji gbanwee nd?. Mgbe any? na-ebuli ihe ????? mmanya n'ihu ?l? ah?a ?l? ah?a, ihe any? na-ah?r? ab?gh? naan? ?t?, kamakwa votu na ah?ike, ?kp?r? omume na echiche az?mah?a. Eleghi anya ezi amamihe nke sayensi di na ngh?ta: Ngwugwu ut? abughi nchighari, kama itule.