N'ihe gbasara nri nri,vitamin Ed? ka "ube isi." ?t?t?vitaminOmume na-ar? ?r? d? ka coenzyme na mmeghachi omume kem?kal?, na-ar? ?r? inyeaka, na vitamin E b? ihe p?r? iche, na ike ya siri ike iji chebe ah?ike mmad?. Vitamin E b? nke an? ah?ab?ba-solubleEzin?l? vitamin ma b?r? ihe nr?p?ta nke benzodihydropyrane nwere usoro yiri ya na ?r? ndu, ?kachas? g?nyere tocopherol na tocotrienol. A na-ekewa otu ? b?la n'ime ?d? an?, α, β, γ na δ, d?ka ?d?iche d? na ?n?d? methyl na mgbanaka benzopyrane, ng?k?ta nke ?d? 8, na nd? isomers nd? a nwere ikike antioxidant. Free radicals b? klaas? nke ?m? irighiri ihe na-ad?gh? akw?si ike nwere mmeghachi omume kem?kal? d? elu nke emep?tara na nhazi nke ah?. ìhè ultraviolet, mmet? gburugburu ebe obibi na ihe nd? ?z? d? n'èzí nwere ike ime ka mmep?ta nke free radicals, na mitochondria b?kwa ebe a na-emep?ta radical free mgbe mkp?r? nd? na-ar? ?r? aerobic metabolism iji nye ike. radicals n'efu na-akpata nr?gide oxidative, nke na-awakpo macromolecules d? nd? d? ka lipids, protein na DNA n'ime sel, na-ebute mmebi oxidative. N'oge d? oke egwu, vitamin E na-adabere na usoro phenolic hydroxyl ya iji nye atom hydrogen iji meghachi omume na radicals efu, na-ebelata radicals free, na-egbochi mmeghachi omume oxidative, wee si otú a na-echebe mkp?r? nd?.

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Ab?ba-solubility nke vitamin E na-eme ka ekesa ya nke ?ma na mpaghara nd? nwere lipids, d? ka akp?kp? an? cell na lipoproteins. Na sa?t? nd? a, ? na-egbochi peroxidation lipid. Mgbe free radicals na-awakpo polyunsaturated ?d?d? ab?baacids, na-akpalite mmeghachi omume nke lipid peroxidation chain nke na-emebi akp?kp? ah? cell na lipoproteins, vitamin E nwere ike ?kw?s? mmeghachi omume ah? na mmalite mmalite na nnyefe, na-echebe lipids na eriri af?, ?bara, an? ah? na akp?kp? an?. N'ime sistemu obi,vitamin Ena-ebelata mmep?ta nke lipoprotein d? ala oxidized site na mmet?ta antioxidant, na-ebelata mmebi ya na sel endothelial vask?la, wee gbochie nhazi na mmepe nke atherosclerotic plaque. N'otu oge ah?, vitamin E nwekwara ike ?hazi mm?ba na mbughar? nke mkp?r? nd? an? ah? d? nro nke vask?la iji n?gide na-enwe nchekas? nk?t? na ngbanwe nke ar?a ?bara. Vitamin E na-ekerekwa òkè d? mkpa na nhazi usoro mgbochi nke ah?. ? na-akwalite mm?ba na ?d?iche d? iche iche nke mkp?r? nd? na-al?so ?r?a ?g? d? ka lymphocytes T na B, na-eme ka mmek?r?ta d? n'etiti mkp?r? nd? d?kwuo mma, ma na-eme ka nzaghachi mgbochi ah? d?kwuo elu. N'otu oge ah?, ? na-ekere òkè na nhazi nke nt?ghar? mgbaàmà cell cell, na-emet?ta nzuzo nzuzo na nkwup?ta nke cytokines, ma na-ach?kwa nzaghachi mgbochi. Isi ihe sitere n'okike nke vitamin E g?nyere mman? ihe oriri, mkp?r? osisi, mkp?r? osisi na akw?kw? nd? akw?kw? nd?. N'ime isi mmalite nd? a, mman? ihe oriri b? ihe kas? baa ?garanya na vitamin E, kar?s?a n'?d? alfa-tocopherol. Na mgbakwunye, enwere mgbakwunye multivitamin E na ah?a, g?nyere softgel, mbadamba ?r? na ude, nke dabara maka mkpa nke otu d? iche iche nke nd? mmad?. Dabere na oriri nt?aka nri nri, ihe akwadoro nke vitamin E maka nd? okenye b? 15 mg kwa ?b?ch? (a t?r? ya na alfa-tocopherol nhata). Agbanyegh?, data nyocha n'ezie na-egosi na nkezi vitamin E nke nd? okenye na-eri site na nri ha kwa ?b?ch? na-ab?kar? ihe na-erugh? 10 mg. ?f?d? ?m?m? egosila na na ?gw?gw? adjuvant maka ?r?a ?f?d? d? ka igbu oge ?ka nká na imeziwanye nkwar? ?g?g? isi, ?gbakwunye 200-800 mg nke vitamin E kwa ?b?ch? nwere ike inwe mmet?ta ?f?d?. N'ozuzu, vitamin E nke ?n? na-ad?gh? ize nd?, mana ???biga mmanya ókè ogologo oge (kar?a 1,000 mg kwa ?b?ch?) nwere ike ime ka ohere nke mmeghachi omume d? nj? d? ka ?bara ?gb?gba. Ya mere, mgbe ? na-eji vitamin E mgbakwunye, ? d? mkpa ?gbaso nd?m?d? nd? ?kachamara iji h? na nchekwa na ezi uche nke mgbakwunye ah?.