Yist beta-glucan b? polysaccharide na-ar? ?r? nke sitere na mgbidi cell nke yist. N'af? 1941, Dr. Pillemer ch?tara ihe d? n'ah? mgbidi sel yiast nke na-eme ka ah? sie ike. Na 1961 Riggi ch?p?tara ihe a na-ar? ?r? na glycan yist d? ka beta-glucan [1]. Isi mmalite nke beta-glucan na-ag?nyekwa oat, fungi, ah?h?a mmiri, wdg, n'ihi na ah? enwegh? ike ?mep?ta ma ? b? zoo beta-glucan n'onwe ya, ?wa nke d? n'èzí ga-agbakwunye ya.

Na mgbakwunye na mgbidi β-glucan na yist cell, e nwekwara mannose na-agbaze mmiri na obere chitin, β-glucan ruru 30% ruo 60% nke ?d? ar? nke mgbidi cell, n'ime ime ime mgbidi cell, b? nke polysaccharide structural, isi physiological ?r? b? ?n?gide na-enwe ike na-ar? ?r? nke mgbidi cell na-ar? ?r? physiological nk?t?. Misaki et al. ch?p?tara na nhazi nke yist β-glucan b? nke kachas? nke β-1, 3-bond, ma nwee ak?k? ?f?d? nke β-1, 6-bond residues.

Mmet?ta immunomodulatory nke yist beta-glucan dabere na ebumnuche ya ziri ezi, ikike ya ijik? nd? na-anabata ya kp?mkwem n'elu sel nd? na-al?so ?r?a ?g?, ebe ? na-akwalite ?r? phagocytosis nke macrophages. Usoro a na-eme ngwa ngwa na-ebuli nzaghachi mgbochi nke an? ah? ma na-edobe nguzozi kachas? mma nke usoro ah? ji al?so ?r?a ?g?.

Beta-glucan na-eme ihe b? isi site na ijik?ta ?d? nnabata beta-glucan at? [4]: ??(1) Dectin-1 receptor; (2) CR3; (3) Nd? na-anabata nd? ?z?, g?nyere onye na-anabata ihe scavenger na LacCer. Mgbe yist β-glucan na-abanye n'ah? mmad? ma jik?ta ya na onye na-anabata ya, ? ga-eme ka phosphorylation nke intracellular d?gh?zi receptor tyrosine motif (ITAM) na Syk, na-ar? ?r? PI3K / Akt ?z?, nke n'ikpeaz? na-eduga na phagocytosis, microbial ?nw? na cytokine nt?hap?, nke mere na mba ?z? na-ewep? nje virus. Ma mgbe ah? ? ga-enweta mmet?ta nke mgbochi.

Uru ah?ike an? ah? nke beta-glucan na-egosip?takar? n'ak?k? nd? a [6]:

1) Ike antioxidant: β-glucan nwere ihe antioxidant, nke nwere ike igbochi ?gb? nke superoxides na ?d? oxygen nd? ?z? na-emeghachi omume (ROS) ma belata mmebi nke nr?gide oxidative na akp?kp? ah?.

2) Mmet?ta moisturize: Site na ?d? ar? ya d? elu, β-glucan nwere ikike ijik? mmiri siri ike, nke nwere ike ijik?ta mkp?r? nd? mmiri nke ?ma n'elu sel akp?kp? ah?, gbochie ikuku mmiri, ma belata mmiri na-efu site na epidermis (TEWL). T?kwas? na nke ah?, ? na-emep?ta ihe nkiri nchebe n'elu akp?kp? ah?, na-enyere aka ?n?gide na-enwe mmiri na ?d? nro na akp?kp? ah?.

3) Nr?zi akp?kp? ah? na ikike ?gw? ?r?a: Seo et al. ch?p?tara na isi mmalite d? iche iche nke beta-glucan nwere ike ?kwalite mbughar? nke keratinocytes mmad? (HaCaT) na fibroblasts akp?kp? mmad? (HDFa), ma mee ka mmechi ?nya na iweghachi epithelialization na ?d? òké [7]. Na mgbakwunye, ihe nd? na-egbochi mkpasu iwe na mgbochi mkpasu iwe nke beta-glucan na-enyere aka belata mbuf?t na ?bara ?bara ma mee ka akp?kp? ah? d? nro. Nnyocha e mere na Journal of Therapeutic Dermatology gosiri na beta-glucan b? ihe mgbakwunye d? irè na ?gw?gw? nke obere atopic dermatitis (eczema) [8].

4) Mmet?ta mgbochi ?ka nká: Beta-glucan na-enyere aka belata ihe ?r?ba ama nke ?ka nká akp?kp?, d? ka wrinkles na sagging. ? na-akwalite njik? nke collagen na ihe nd? ?z? akp?kp? an? extracellular matrix (ECM), na-am?ba ?kp?r?kp? na elasticity nke akp?kp?.

Na mgbakwunye, beta-glucan nwekwara ?r? nke ?hazi ah?h?a eriri af?, ibelata cholesterol, mgbochi ike ?gw?gw?, ah?ike ?kp?kp? na nd? ?z?.

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