I roto i te mara rangahau hauora whekau, kua roa te Polydextrose kua whakarōpūtia hei muka kai-wairewa noa. Heoi ano, he maha nga rangahau hou i roto i nga tau kua pahure ake nei kua whakaatu ko tenei ngota ngota waihanga i polymerized matapōkeretia mai i te kūhuka he tino "kaitakaro maha" e whakahou ana i te microecology intestinal na roto i te tikanga e toru o te "whakaritenga viscosity hihiri - te kai tika o te microbiota - tauhohenga riipene metabolite". Ko te rangahau hou i roto i te Nature Gastroenterology i te 2024 e tohu ana ko te kai o ia ra o te 10-15g o te polyglucose ka taea te whakanui i te tika o te arai whekau e 37% me te whakaiti i te taumata o te IL-6 i te 29%. Ko tenei kitenga ehara i te mea ka huri noa i te mohiotanga tuku iho engari ka ara ake ano he ngaru tono whakawhiti mai i te umanga kai ki te rongoa haumanu.

?

Youdaoplaceholder0 Upoko 1 Putaiao Wetewete: Ko te "Maramatanga katoa o te ngongo ngongo" o te ngota ngota ?

Youdaoplaceholder0 1.1 Viscosity deformation: Ko te "whakautu mohio" mai i te puku ki te kopirua ?

Ko te ahurei o te polydextrose kei roto i tana huringa pokey Ph-whakaaro:

?

Youdaoplaceholder0 Pupu ? (pH 1.5-3.0) : Ka honoa nga mekameka ngota i roto i nga here hauwai hei hanga i te hanganga whatunga ahu-toru, he hopi pokey tae atu ki te 1500 mPa·s, ka whakaheke i te reiti putunga puku ki runga ki te 45% (whakaritea ki te 20% noa iho o te whakaraeraetanga o te kai noa), he nui noa atu te whakaraeraetanga o te muka.

Youdaoplaceholder0 Kohanga iti ? (pH 6.0-7.4) : Kua pakaru nga here hauwai, ka heke te pokey ki te 400 mPa·s, ka whakahekehia e te waikawa bile te whakaurunga o te cholesterol ma te 18% me te kore e pa ki te whakauru matūkai;

Youdaoplaceholder0 Colon ? (pH 7.0-7.5): Ka timata te fermentation microbial, ka pakaru te pokey ki raro i te 50 mPa·s, ka tukuna nga waikawa ngako mekameka poto (SCFA), me te piki o te waikawa butyric e 3.2 nga wa, ka whakahohe tika i te hanga o te intestinal epithelial cell1 (Figure epithelial cell repair).

Youdaoplaceholder0 Hangarau Painga ? : Ka taea e te hangarau SmartVisc? a DSM te whakarite i nga pihi pokey mo nga waahanga rereke ma te whakarite i te tohu o te polymerization (DP uara), penei i te tauira G-momo i hangaia mo nga turoro me te reflux gastroesophageal, e hanga ana i te kiriata whakamarumaru tinana me te viscosity tae atu ki te 2000 mPa·s i roto i te puku.

?

Youdaoplaceholder0 1.2 Ture Microbiota: Mai i te "whangai whaanui whanui" ki te "hua whai hua" ?

He maha nga wa ka whakaihiihihia e nga prebiotic tawhito nga microbiota katoa, ko te polydextrose e whakaatu ana i nga mana whakahaere tika:

?

Youdaoplaceholder0 Te aukati ki runga ? : Ko te ahua pokey teitei ka hanga he arai tinana i roto i te koroni tata, ka aukati i te piri o nga huakita pathogenic (pērā i te Escherichia coli), ka whakaheke i te tere o te koroni pathogen e 52%;

Youdaoplaceholder0 Whakanuinga o te awa ? : Ko nga kongakonga oligosaccharide i tino whakamahia e nga huakita whai hua penei i te Bifidobacterium me Roseella, a ka piki ake te nui o te 68% i muri i nga wiki 8 o te wawaotanga (i runga i te raupapa metagenomic);

Youdaoplaceholder0 Metabolic synergy ? : Ko te waikawa Butyric e whakaputa ana ka whakahohe i te kaikawe GPR109A, ka whakaawe i te rereketanga o nga pūtau T, me te arotau i te taupae toenga aukati intestinal ki te 0.91 (te paepae hauora> 0.85).

Youdaoplaceholder0 Upoko 2 Taupānga Awha: Parakatihi Whakawhiti Taitapa mai i te Ripanga ki te Moenga Hohipera ?

Youdaoplaceholder0 2.1 Ahumahi Kai: Ko te "Mihini e kore e kitea" me nga mahi kua whakahoutia ?

Youdaoplaceholder0 Baking Revolution ? : Kua whakawhanakehia e te Roopu Meiji o Japan nga pihikete kore-sucrose ma te whakamahi i te kaha pupuri wai (8.3g wai / g) me te pumau o te waiariki (te manawanui ki te 220 ° C) o te polyglucose, me te whakaheke i te rereketanga o te huka toto i muri i te kai ma te 41%.

Youdaoplaceholder0 Inovation Inovation ? : Nongfu Spring's Intestinal Sparkling Water, e whakamahi ana i te taonga hanga hau fermentation koroni o te polyglucose ki te whakaora i te paopao me te kore e whakapataritari, neke atu i te 8 miriona nga ipu i hokona i tana marama tuatahi i runga i te maakete;

Youdaoplaceholder0 Whakakapinga Kai Whakakapinga ? : Ko te Soylent i te US e whakamahi ana i te tauira viscosity-gradient ki te whakaroa i te roanga o te puhoi-whakaputa ki te 6 haora me te whakapai ake i te manawanui o nga kaiwhai marathon ma te 23%.

Youdaoplaceholder0 2.2 Te kai haumanu: Ko te "arai arai intestinal" mo nga turoro ICU

Ko te rangahau RCT o Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University (n=204) e whakaatu ana:

?

Youdaoplaceholder0 Te aukati mate ? : I roto i nga turoro ICU kua taapirihia ki te 15g o te polydextrose ia ra, ka heke te mate o te sepsis enterogenous e 44%;

Youdaoplaceholder0 Te whakatikatika mucosal ? : Plasma ligonin (he tohu mo te uruhanga intestinal) kua heke te taumata ma te 31%, ka piki ake te kiato pūtau kapu ma te 39%;

Youdaoplaceholder0 Immunomodulatory ? : I piki ake te kukū o te Serum IgA ma te 28%, ka hoki te ōwehenga pūtau CD4+/CD8+ T ki te awhe noa.

Youdaoplaceholder0 Upoko 3 Te Hurihanga Hangarau: Mai i te Hoahoa Molecular ki te Kai Tino Whakahohe AI ???

Youdaoplaceholder0 3.1 Hanganga whakarerekētanga: Wewete Whakaritenga i runga i te tono ?

Youdaoplaceholder0 Te pokey ? : Na te whakauru i nga mekameka taha sorbitol, i whakawhanakehia te polyglucose wawahanga motuhake o te koroni (momo C), ka tino heke iho tona pokey ki te 10 mPa·s i te pH 7.0, mo te hunga e paopao ana;

Youdaoplaceholder0 Tikanga Whakarei ? : Roguet, Parani, i whakawhanake i te hangarau microcapsule Probiocoat? e mau ana i te probiotic i roto i te matrix polyglucose, me te whakanui ake i te reanga ora o te waikawa pekitiki mai i te 15% ki te 92%.

Youdaoplaceholder0 3.2 TE WHAKAMAHI AROHA: Ka pakaru te Waehere o te wawaotanga Whaiaro ?

Ko te punaha "Digital Twin of the Intestine" i hangaia e NutriAI, he kamupene o Iharaira, he 200,000 nga keehi o nga raraunga tipu whekau tangata me nga tauira hihiri wai, ka taea te tohu i te whakautu a te tangata ki te polydextrose:

?

Youdaoplaceholder0 Dose optimization ? : Ko te 8-12g/ra + fructooligosaccharide tikanga whakakotahi i taunakihia mo nga turoro IBS i whakahekehia te mate o te pupuhi o te puku ma te 67%;

Youdaoplaceholder0 Scene fit ? : He tātai whakakorikori tino kaha kua whakaritea mo nga kait?karo, e whakanui ana i te fermentation koroni e 40% me te karo i te mamae o te kopu i te wa e whakangungu ana.

Youdaoplaceholder0 \ n \ nWahanga Tuawha: Hurihuri Ahumahi: Te Pakanga Hangarau i roto i nga Maakete Tiriona taara ?

Youdaoplaceholder0 4.1 Reihi Kaha: Ka eke nga kamupene Hainamana ki runga i te pihi ?

Youdaoplaceholder0 Baolingbao Bio ? : Haumi 800 miriona yuan ki te hanga i te turanga hanga polyglucose nui rawa atu o te ao, hangarau whakahiato enzymatic ki te 99.9% te ma;

Youdaoplaceholder0 Hualixi Biotech ? : I whakawhanakehia te polyglucose nano-fibrotic, kua piki ake te viscosity regulation sensitivity i te 4 wa, i whiwhi i te whakaaetanga kai a te Medical Special NMPA;

Youdaoplaceholder0 Tahora Transnational ? : Kei te mahi tahi a DuPont me te Mayo Clinic ki te ahu whakamua i tetahi whakamatautau haumanu Wāhanga III mo te polydextrose hei aukati i te mate pukupuku colorectal.

Youdaoplaceholder0 4.2 Wero Whaiaro: Te Aputa mai i te Taiwhanga ki te maakete papatipu ?

Ahakoa te nui o nga taunakitanga pütaiao, e whakaatu ana te rangahau a nga kaihoko e:

?

Youdaoplaceholder0 Knowledge Blind spot ? : 31% anake o te iwi e mohio ana ki nga rereketanga mahi i waenga i te polydextrose me nga muka noa;

Youdaoplaceholder0 Pohehe inenga ? : 45% o nga kaihoko e whakapono pohehe ana "he pai ake te pai ake", ka raru pea te ahua o te pupuhi;

Youdaoplaceholder0 Whakautu Ahumahi ? : I tukuna e te Hainamana Nutrition Society te Pepa Maama mo te Whakamahinga o te Polydextrose, me te whakarite i te paepae haumaru o te 15g ia ra.

Youdaoplaceholder0 Upoko 5 Tirohanga a meake nei: Te tautuhi ano i te 'Taenga Ataata' ?

Youdaoplaceholder0 5.1 Tuaka Tuaka Roro-Gut: He Piriti Molecular mai i te Putu ki te Kare-a-roto ?

Ko nga whakamatautau kararehe hou i te California Institute of Technology kua kitea:

?

Youdaoplaceholder0 Te whakamaaharahara ? : Ko nga kiore i roto i te roopu wawaotanga polyglucose i whakanui ake i te wa torotoro i roto i te whakamatautau maze e 53%;

Youdaoplaceholder0 Mechanism tracing ? : Ko te waikawa Butyric ka whakahohe i te whakaaturanga BDNF i roto i te hippocampus na roto i te arai toto-roro, ka piki ake te kiato synaptic e 29%.

Youdaoplaceholder0 5.2 Koiora Hangaia: Ko te 'Puka Whakamutunga' o nga muka kua whakaritea ?

Ko te kamupene Ginkgo Bioworks i te United States kua whakarereke i nga riu rewena ma te whakamahi i te hangarau CRISPR-Cas9 ki te huna tika i te "polydextrose-whakawaehere ira" me nga mahi kua whakaritea:

?

Youdaoplaceholder0 Whakaritenga tika ? : Ka taea e ia te whakaihiihi i te tipu o Achaemenia, a ka piki ake te nui o te 80% i roto i nga tauira momona;

Youdaoplaceholder0 Whakautu Maamaa ? : Ko te pūoko pH hanga-i roto, ko te tika o te huringa pokey kua pai ake ki te ±5 mPa·s, e tika ana kia uru ki nga whakamatautau haumanu a te 2026.

Youdaoplaceholder0 Whakamutunga: I te wa e tutaki ai te Matauranga molecular i te Gut Ecology ?

Ko te haerenga putaiao o te polydextrose he hitori o te hokinga mai i te "ahua-ahua-ahumahi" ki te "kaihanga kaiao intestinal". E kii ana ki a maatau ko nga pakaruhanga pono i roto i te hauora he maha nga wa i ahu mai i te whakahekenga hohonu me te whakatikatika i nga rohe o te tino o te matū. Ka rite ki ta Jennifer Doudna te toa Nobel i kii, "Ko te koiora waihanga e whakaako ana i a tatou ka taea e nga ngota ngota te whakawhiwhia ki te 'kaha ki te whakaaro'." I roto i tenei huringa hangarau o te hauora whekau, ko te polydextrose noa te timatanga - ka maha ake nga "ngota ngota mohio" ka uru ki te pakanga, ka mutu ka tutuki te tangata i nga tikanga tika mo nga mate maataki.