????? ??????: ?????????? ?????? ?????? ?????????

?.? ???? ???? ????????????? ?? ????????????????? ????????????
???? ????? ???????? ?????? ???????????????? ??????????? ????? ???????? ???? ????????, ???????? ????????? ????????? ???????????? ???????? ?????? ?????? ?????? ??? ????:
- ???? ?? ???:??????? ???? ???? ???? ???? ???????? ???? ?????? ?????? ????.
- ???? ?? ???:??? ????? ??? ?? ?? ???????? ???? ???????? ????? ???? (?????-?????? ???????? ??? ???? ????????? ??% ??? ????????)
- ???? ?????,??????????? NIH ?? "??????????????? ??????" ???? ?? ?????? ?????? ?????? ?????? ???????? ????.
?.? ?????? ???????????? ?????? ???
??????????? ?????????? ?????????:
???? ????? ?????? ?????? ?.? ???? ??????? ???????? ??????? (??????? ??.?%)
??????? ????? ??????????????? ??????? ???? ??? ??????? ???% ????? ???.
????????? ??????? ???? ???:
????????????????? ??????????? (MMSE ??????????? ?.? ??????? ???????)
??????? ?????? ?????? (GOS ???????? ????? ?.? ??????? ?????)
?????? ???: ???? ????????? ?????-????? ????????
?
?.? ?????? ???? ?????
?????? ?????? ?????????? ?????: ?????????????????? ???????? ???????? ?????? ?????? ??????? ???? ???? I: ????????????? ????????? ???????????????? ??????????? ??????? ???? IIA: ???????? ??????? ?????? ????? ???????????????? ??????? ??????? (????? ??% ?? ?????) ???? IIB
?
?.? ???????? ?????? ????? ???????
?? ???-??? ?????????????? ??????? ?????? ??????????? ???? ????? ???????? ?????????? ??? ????? ??? ???:
???????? ????????????? ? ????????? ?? ???? ????????? ???????????? ???????? ??????? ???????? ??????????? ??? ?.? ???? ?????? ???? ????.3
?????, ?????? ?????????? ??????? ?? ??????????? ????? ???? ?????? ?????????????????? ??????? ???????????? ??? ?????? (p=?.??).
????? ??????: ?????? ?????
?
?.? ?????????? ????
???? NICE ?????????? ???????: ??? ????? ???? ?? ?????? ???? ?????????? ?????? ?????????? ???????? ?????? ????? ???? (?????-????????? ???????? £??,???/QALY)
??????? ?????????? **???? ????-????????: ????? ???????????? ?????? ???? ?????????????? ??????? ???????????? ??? ???? (p=?.??)
?.? ?????????? ??????????? ?????
????????? ???????? ???????? ?????????? ???? ?? ????????:
???? ?????????? ????? ??????????????? ???? ("??????????? ?????" ?? "????????? ??? ????" ?????? ?????????? ????)
??? ??????? ?-?????? ?????????????? ??????? ????????? ?? ??% ????? ??????????? ????????? ??????? ???? ???????? ??????????? ??% ?????? ??? ???.
?????? ???: ???????? ?????????? ????
?
?.? ???? ??? ????? ???????
????-????? ????? ???? ???????? ??????? ????????? (?????? ????????? ????? ?????, CN202410123456.7)
????????????? ??? ????????? ??????? ???? (?????? ????????? ??? ????????? ????????????? ????????????? ????????????? ???????????? ?????? ??? ????? ??? ???)
?
?.? ?????????? ??????? ???
?????????? ??????? ???????? ??? ????? ??? ??? ??:
??????-????????????? ??? ??????????? ??????????? (?????? ????????????? ??% ????) ??????? ?????? ??% ?? ????? ???.
?????? ??? ????????? ???????? ?????? ????
?
?.? ???????? ???????
??????????? ??? ?????? ??????????? ???????: ??????? ???????????, ???????? ????????? ???????? 62 ?????? ???????? ???????? ???? ?????? ????? ?????? 32% ???? 89% ?????? ???????.
?.? ???? ??????? ??????? ?????
"??? ????? ???? ?????????, ??? ???????? ????? ????????? ???? ????? ????? ????" - ?????????? ????? ?????? ?? ??????? ????????? ???????