????????? ??????? ???? ??? ????????? ??? ???? ?? ?? ???? ??????? ????? ???: HMB-Ca
????? ?? ??? ??????? ??????? ?????????? ???? ???? ???????? ????? ?????? ????? ????. ?????? ???? ???????????? ????? ?????? ??? ????? ?? ?????????? ??????? ????????? ?????????? ?????? ??? ???????????? ??????? ????? ?? ?????????? ?????????? ???? ????. ????? ??? ?????? ??????? ?????? ????????? ??????? ??????? ????????? ??? ?????.??????-???(β-???????????-β-????????????????), ?? ??????????? ????? ?????????? ????, ?? ????????????????????? ??????? ?????????? ????????? ???? ????? ???? ???.
?
????-???????????-????-??????????????? ????? (HMB) ?? ??????????? ???, ??????????????? ???? ??????, ??????????????? ?????????? ??? ???? ???? ??? ??????? ?????????????????? ?????? ???????? ?????. ????-???????????-????-??????????????? ????? (HMB), ????????? ?????????? ??????, ?????? ???????? ??????, ????????? ????? ??? ???? ??? ????-?????? ?????? ????????. HMB ?? ????? β-???????????-β-??????????????? ???????? ????? ??????? (??????-???) ?????? ???? ??? ??? ????????????? ?????? ????????? ?????? ???? ???, ?? ?? ????? ??????? ?????? ????? ?????:
?, ??????????? ????? ????? ??????????, ???????????? ????? ????????????, ???????? ??????????? ??? ??? ???????? ??????????? (LDL) ?? ????? ??? ?????????? ??????? ??????? ??? ???? ? ?????????????????? ??????? ???? ??? ??????????, ????? ????? ????????? ????????? ?????? ????????????, ?????? ?????????? ????? ??????????? ????? ?????? ????;
?, ????, ??? ??? ????????? ??????, ???? ????????, ?????? ??? ?????? ????????, ????, ????? ?????, ????? ???????? ???? ??????? ????? ??? ????, ?????? ?????? ?????? ?????? ≤? ?????/???? ???; ?, ???????? ??????? ??? ??? ???? ??????????????? GRAS ???????, ???????? ???? ???? ??? ????? ?????????? ?????????? ????????. ??????? "????? ???????? ??? ??? ?????? ?? ????????? ?????????? ??????? ??????? ????" (GB ?????-????) ???? ????? ? ??? ????? ? ?????, ??? ??? ????????? ?????? ???? ?????????????? ?-? ?????/???? ????? ??? ????.