SAIB: ??????????????? ???????????????????, ???????????? ????????????? ?????? ?????
???????? ??????? ????????????? ??????, ??????? ?????????????? (SAIB) ?? ????????? ????? ????, ???, ??????????????? ??? ???????? ????????? ???????? ???????? ???????? ????????????? ??? ??????? ????????? ????????????? "????? ????? ???" ???? ???. ???? ??????, ?????? SAIB ???????? ?.? ???? ??????? ???????????? ????? ???????? ??????? ???, ?? ?.?% ???? CAGR ?? ???? ???.
?. ???? ??????: ???????? ?????? ???? ??? ?????? ?????????? ?????? ????
???? ??????????? SAIB ?? ????? ????? ?????? ?????? ???????????? ??? ???????. ??????????? ???? ?????? ?????? ????????, SAIB ?? ???? ???????? ???? ??? ??? ???????? ???????? ??? ??????? ?????? ?????????? ???? ????, ???????? ??????????? ?? ???????? ??????? ?????? ???? ???????? ???? ??? ?? ???? ?????? ???? ? ???? ?????, ?????? ??? ?????? ????-???? ??????? "???? ???????? ??????????? ????" ?? ?????? ???? ????, ?? ????????? ?????????? ??????????? SAIB ??????. ?????? ???? ??????? ??? ?
?
??????? ?????????????? ????? (???????) ???? ?????? ???????????, ?????????? ??????????? SAIB ?? ??????? ????? ????????? ?????? ?? ?????/???? ??? (???? ????????? ??????, ????????? ??????? ???? ?.?? ?????/???? ???), ??? ?????? ?????????? EU ???? EFSA, ???????? ??????????? FDA ??? ???? ?????? ????????? ??????? ?????????????? ???????? ???? ???.
?
?. ??? ??????: ???????? ????????? ??????-????? ???????????? ??????????? ??????.
???????? ?????????, SAIB ???? "??? ?????? ????? ??? ???? ????????? ?????" ?? ????????????? ???? ???? ????? ???. ???? ???? ??????????, ?????? ?????? ?? ???????????? ??? ?????? "Risperidone Long-acting microsphere storage System based on SAIB" ?? ???????? ???????? ????, ?????? ???????????? ??? Risperidone ?? ?? ???????? ????? ???? ???????????? ?? ???????????? ??????, ????? ????????? ?? ?.??% ?????? ??? ???? ??? ????????? ??? ????????? ?????? ?????? ??????????? ??% ?????? ????? ???????. ?? ??????????? ?????? ???? ???????? ???????????? ????????? ?????? ??????? ??????? ???? ???.
?
???????, ?? ??????? ??? ??????? ??? ?????? ???-????? ????? ?? ??????????? SAIB ?? ?????? ???????? ??? III ????? ???????? ?????? ???? ???. ??????? ??????? ????? ???? ??? ?? ??????? SAIB-?????? ???? ?? 2026 ????? ?????? ???????? ??????? ???, ????????? ??????? ???? ??????? ?????????? ?? ??? ????.
?
?. ??????????????? ??? ??????? ????: ???????? ??????? ??? ?????????????? ?????? ???????
SAIB ?? ???? ????????????????????? ????? ???????? ???? ??? ?????????? ?????? ???? ???? ???????? ??????????? ????????????? ??????? ??? ???????? ????????????? ?????. ????? ???? ?????, ?????? ?????? ????? ??????? ??????????-?????? ????? ???????? ???????? SAIB ?????? "????-??? ?????" ???????? ???? ????, ???????? ???????? -??°C ?? ??°C ???????? ??????? ???? ???? ??? ???????????????? ???????? ??% ? ?? ??? ????.
?
??????? ???????? ??????????? ?????????, ??????????, ???????? ??? ?????? ??? ??? ??????? SAIB ?? ???? ???????? ??????????? ????????????? ????? ???? ????? ???????? ?????? ?????????? ?????. ???????????? ??? ????? ??? ??? ?? ?.?% SAIB ?????? ??? ??? ????????? ???????? ??% ?????? ????? ???????????? ????? ????? ???? ???? ??? ??????? ??????? ???? ??? ????.
?
? ???, ???????? ????????: ???????? ????????? ??? ????? ??????? ?????? ????? ?????? ?
??. ????? ???????? ??????????????? ??????? ???? ??? ???? ?
????????? SAIB ??????? ????????? ?????? ??????????? ??? ????????????? ??????????????? ?????????????? ??????? ????, ????????? ???? ????? ???? ??? ???? ??-????????????? ?????? ?????. ???? ?????, ????? ????? BASF ?? ?????? ????????? ??? ?????? ???????? ?????????? ?????? ????, ???????? ??????????? ?????? ???℃ ???? ??℃ ?????? ??? ????, ??????? ?????? ???? ?? ??% ?????? ????? ??? ?????? ???????? ??% ?? ?? ??? ????. ??????? ???????? ???????????? ?? ????? ????????????? ?? ????????????? ???????????? ??????? ??? ???, ?????? ??????? ??????? ?????? ?,??? ? ?? ???.
?
?. ?????????? ?????????? ????????? ????????? ????
???????????? ??? ??????????? ????????? ?????????? ?? ???? ???? SAIB ?? ??????????? ??? ??? ???????? ???? ??????? ????. ??????????:
?
? ??????? ????????? SAIB? : ???????? ????? ???????? ?????? ?????? SAIB-PEG ????????, ??? ??????? ?????????, ?????????? ????? ?????????-????? ??????????? ??? ???? ?????????? ?????? ????;
? ???? ???????? SAIB? : 3M ?? ???? ???? 3D ????????? ??? ???????????? ???? ???, ???????? ???????? ??? 5 ????????????? ??? ???? ??? ??? ????????????? ???????? 20% ?? ????? ???.
?????, ?????? ???????????? ????????: ????-????? ??? ????????? ??????? ?
??. ?????-??????? ?????? ?? ???????? ?? ????? ???? ??? ?
??? ??? ???????????? ????????? ??????????????? SAIB ?? ????? ????? ???. ?????????????, ???? ?????, ??????? SAIB ?????? ???????????? ??% ??? ????, ?? ???????????? ???? (??%), ???? (??%) ??? ??????? ??????????? (??%) ?????? ??? ????. ???????? ???? ?????, ??????? ????????? ?????? ??????? SAIB ?? ???? ???????????? ????????????? ?????????? ??????? ???????? ???????? ????, ?????? ?????? ??????? ??????? ?????????? ?????? ???? ?????? ?? ????.
?
??. ???????? ?????????? ?????????? ??????? ????? ??????? ????.
???????? ?????????? ?????? ????? ???? (SCS) ????? ???? ?????? ??% ??????????-?????? ????????????????? ??????? ???????? ????? ???? ???. ???-?????? ?????? ?????? SAIB, PVC ????? ??? ????????? ??????????????? ????????? ?????? ???? ????? ???. ??????? ?????-?????? ????? ??????? SAIB ????? (???? ????? ??? ??????? ???? ?????) ?? SAIB-?????? ???????????? ??????? ???? ?????? ???? ?? VOCs ???????? ?.?ppm ?????? ??? ?????.
??. ????? ??????? ??????? ????? ???????? ??? ????? ?
????? ???? ??????, ???? SAIB-??????? ??????? ???? ?????? ?,??? ?????? ????? ???? ???, ???????? ????????? ??? ????????? ?????? ??? ?????????? ????? (IFF) ????? ????? ????? ????? ??% ?????? ??????? ???. ???????, IFF ?? ?????? ?????????? CJ ??????? ????????? "SAIB-????????????? ??????? ???????????? ????????????? ??????? ??????????? ???? ???? ????, ???? ??? ?????? ??????? ???????? ???? ????, ???????? ??????? ????? ????????????? ???????? ?????? ????? ??????? ????.
?
? ??????? ??? ???????: ???????? ??? ?????????? ?????? ?
SAIB ???? ??????????????, ?????? ?????? ??? ?????? ?????????? ????? ????? ?????:
?
? ??????? ???????? ????????? ????? ? : ?????? ????????? ???????? ?????? SAIB ???? ????????? ????????? ?????? ?????, ???????, ?????? ??? ??? ?????? ??????? ??????????? ???????? ??????? ??????????? ???? ??????????? ??? ????? ???.
? ?????????? ??????????? ??? ? : FAO/WHO ?? ??????? ADI ????? 0-10 mg/kg ???? ???, 2024 ????? ?????????? ???? ??????? ???????????? SAIB ???????????????? ?????????? ???????????? ???????? ??????????? ??????? ???? ???? ??? ??????? ?????? ?????? ???? ???? ?
????????, ???????? ???????? ??? ?????????????????? ????????????, SAIB ????? ???????? ??????? ??? ??????? ???? ??????? ????????? ????????? ????????? ?????? ???? ??? ??????? ???. ????????? ??????? ?? ??? ?????? ??? ?????????? (IFT) ?? ????? ???? ??? ?? SAIB ??????????????? ??????? 2030 ?????? $5 ???? ?????? ????? ????, ?? ??? ?????????????? ?? ?????????? ????????? ????.
?
????????
??????????? ?????????? ?????????? ?? ???????? ????????? ????-????? ???????? ?????????, ???????????? ????????????? ?? ?????????? ???????????, SAIB ?????? ???????? ?????????? "?????????? ????????" ?????? ???? ??? ???. ???????? ???????? ??? ???? ?????????? ?????? ?????????????, ???? ??????????????????? ?????? ?? "???? ???????" ????? ??????? ????????? ????????? ??????.