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?? ??????????? ????????, ????????????? (???????????) ????? ????????? ?????????? ?????????? ?????? ??? ????????????? ??????? [58]. ???????????, CDP-????? ????????? ??????, ??? ??? ??????? ????????????? ????????????, ???????? ??? ??????????? ????? ?????? [59,60]. ?????????????? ??? ????? ?????? ??????????? ?? ?????????????? (???) ???????????? ?????????? ?????? ??? ????, ????? ????????? ??????? ??????? ?????? ???? ???? (? ???????????? ???? ??????/????). ?? ?????????????? ??????????? ??????? ????????, ??????????? ??????? ??????? ???? ??? ??????? ???? ??? ???? [61,62]. ??????? ???????? ???????? ??? ??? ???? ????? ????????????, ??????????? (? ???????????? ???-?,??? ??????) ??????? ???? ??? ???? ????? ????? ?????? ???? ????. ?????, ?? ????? ????? ???????????????? ??????, ?????? ??????? ?????? ???? ???? [63,64,65]. ?? ???????????? ?????????????? ??? ???????? ?????? ?? ??????????? ???????????? ????????, ??????? ??????? ?????? ????? ??? ????, ????? ????? ???????? ??????????? ???????? ???????? ???? [66]. ??????????? ?????????????? ???????? 66 ???????????? ???? ????????? ?????? ??????. ?? ?????? ??????, ???? ????? ??? ?????? ????????? ??????? "?????????" ???????????? ??????? ????. ????????? ??????? ???? ????? ???? ??????? ???? ??? [67]. 24 ?????? ????????????, ??????-????? ????????? ???????????? ?????????? ???????? ???? ????????? ??????, ?? ??????????????????? ????????? ??? ?????? ???? [26]. ???????? ?????? ??????? ????, ????? ?????? ????? ??? ???? ???????????? ???????? ????? ?????????? ????????????? ??????? ?????? ?????????? ?????? ?????? ?????.