?????? ??: ??????????? ?????: ?????? ??????? ? ???????? ????? ????? ????
?.? ??????????? ?????? ?????????????? "? ????" ?? ???????
??????? ????????? ??????? GB 28050-2011 ??????, ????? ??? ?????/?????? ≤?.? ????? ???? ???? ??????? "????????" ???? ???????
FDA ????: "???? ?????" ?? ?????????? ?????? ???? ?????????? ????? ????? ??
???????? ????? ????? ???????????: "???????? ?????? ?????" ??????? ??? ?????? ????? ???????????
?.? ??????????? ???????? ???????
??????? (C12H19Cl3O8) ?? ????????????? ??????? ??????? ?????, ?????? ???? ????? ?????? ??????? ??????? ?????, ??:
????? ?????????????? ?????? ?????? (???? ???? ???????)
???? ????????? ?????? ??
?????????? ???????? (GI) ? ??
?????? ???: ??????? ??????????? ??????: ????????????? ??????? ?????? ?????????
?.? ????? ???????????? ????????
???????? ???? ???????? ??? ????????? ?????? ????????? ??????? (????):
????-????? ?????????? ????: ??????? ???????? (SO2Cl2) ??? ???????????? ?????????? ???? ????? ??????????? ??????
?????????????? ?????????: ???????/???? ????????? ???: ???????????????? ??.?% ??????? ????? ???????
??????? ?????: ???? ?? ??? ??????????? ????? ??? ????? ?????????? ????????
?.? ??????? ?????????? ?????????? ????????
?????? ?????? ?????? ?????? "???????-???????? ??????? ????":
????? ??????? ??????????? ??? ?????-?????
?????????? ?????? ??% ?? ????? ??
????? ?? ????????? ????? ?????? ???????? ??% ?? ??????? ??
(????????? ?????? ????? ???????????: ????????? ?????????? ???? ???? ?????? ?????? ??????? ?????????)
?????? ???: ???? ??????? ?????????: ???? ?????? ?????? ? ???????????? ??????????
?.? ?-????? ?????????????? ??????? ?????????? ?????
???? ?? ???????? ????????? ??????? ?????? ??? "????????" ?????????? ?????:
??% ???? ????? ?????? ?????????? ? ???? ?????? ??????????
?% ???? ??????? ????????? ? ???????? ?????????? ????????? ????
?.? ???????? ??????? ?????????
?? ??????? ? ???????????? ??????? ????? ???? ?????? ???????????? ??????? (N=????):
??% ??????????? ??????? ?????? ?? "? ???? = ????? ????? ????????"?
??% ?? ??????????? ????? ???? ????? ???? ????? ??? ?????? ???
???? ?% ?? ADI ????? ??????? ???? ????????
?????? ???: ???????? ????????????? ?????? ????: ??????? ???? ???? ??
?.? ????????? ??????????? ???? ??????
????? ???????? ??????????????? ??? ??-??????? ???? ?? ?? ?????? ????????:
ADI ?? ?????? ????? ??? ???? ??????? ?????? ????????? ????????? β ????????? ???????? ?????? ?????
??????, ???????? ??????????? ???? ???????????? ??????? ???? (p > ?.??)
?.? ???????? ???? ?????????????? ????????
????? ?????? ?????? ???? ????????? ???????? ???? ??????? ???????? ???????? ?? ????? ?????????????:
???????? ??????????? ????? ??? ?? ??? ???? ??????? (? ?????) ????? ??? ?????? ?????? ???? ???????
????????? ? ??????? ?????????? ????????? ?????? ???????????? ?????????? ?????????
???? ????????? ????? ?????????? ????? ???????????? ????? ?????????
?????? ?????? ???????? ????????????: ??????-???????? ???????????? ???
?.? ??? ???????? ????????? ??????????
???????? ??????????????? ?????? ????????? ?????? ???? "????? ??????? ???????" ??????? ??????
???? ???? ??????????? ??????? ?.? ???? ????? ? (???? ?? ?? ????)?
?.? ??????????? ???? ????????????
???????? ????? ????? ??????? ?????? ????? ?? ??????????? ?????? ????????? ?????? ????? ????? ?????? ??
????? ????????? ????????? ?????? "????? ???????? ???????? ???? ????" ??? ????????? ???????