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    ??????????? ????? ?????? ??? ?? ????-?????????? ??????????, ????????? (??????? K3) ?? ????????? ?????????? ????????? ???? ???? ????? ????????? ??????? K ?? ?????? ??????? ??????? ??, ??? ?????????? ????? ?????? ??????????? ??????, ? ???? ??????? ????? ???????? ??? ????? ?????? ????? ???? ? ??????? ???????? ??? ???? ???

    ???????? ??????????? ??????? ? ?? VPS34 ???????????????????? 3-?????? (PI3K) ?? ?? ?????? ?????? ??, ??????????? VPS34 ?? ?????????? ????? ????, PI3P ?? ??????? ????? ????, ? ????????? ???????? ??????????? ?????? ??????????? ?????????? ???? ????? ????? ???? ??????, ??????? ????????? ???????? ?????? ? ??????? ?? ??????? ????? ???? ???????? ????? ?????? ?????? ?? ?????, ????????? ?????? X-????? ?????? ????????????? ?????????? (XLMTM) ????? ???? ???????? ??????? ??? ??????????? ?????????? ?????? ????? ??????? ??

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    ?????? RapidCaP ???? ??????????? ????-?????????? ??????????, ????????? ?????? ??????? (MSB) ?? ????? ??????, ??? ??????? K ?? ???????? ????? ??? ???????? ????? ???? ?? ????? ?????? MSB ?? ????? ?????? ????????? ?????????? ????????? ????? ???? ? ?????? ?????????? ?????? ??????? ???? ?????

    ???????, ???????? ???????? ???????? ????? ????? ?? MSB ??? ???? ????? ?????? ????-?????????? ??????? ????? ????????? ?????????? ????? ????????? ?????????? ????? ????? ???? ??????? ?? ?????? MSB ?? PI3K kinase VPS34 ?? ?????????? ????? ????, PI3P ?? ??????? ????? ????, ? ?????????? ???? ????? ????, ???? ????????? ???????? ??????????? ?????? ???????????? ?? ?????, X-????? ?????? ???????????? ?????????? (XLMTM) ??, MSB ?? VPS34 ?? kinase ?????????? ????? ????, PI3P ??? ???????? ??????? ????? ???? ????? ????????? ???????????? ???? ?????