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Properties of Cysteamine

2025-02-15

Cysteamine (Cysteamine,CS), also known as β-merhydrylethylamine, white crystalline powder, melting point 99~100℃, slightly odorous, soluble in water and alcohol, alkaline reaction. Because it contains active sulfhydryl and amino groups, it has a variety of biological functions. It is a biologically active substance in animals and has important physiological effects. Cysteamine molecules of thiol, easy oxidation air become disulfide often use its hydrochloride (CysteamineHydrochloride, CSH) as a substitute for it. CSH chemical properties are stable, solid at room temperature, strong hygroscopicity, easy oxidation at high temperatures, melting point of 70.2~70.7℃.

CS and its hydrochloride (CSH) are intermediate ingredients in some cosmetics, as well as a hair perm reducing agent, and can be used in the manufacture of other hair dressing cosmetics.

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In the application of hair perms, CSH is generally shortened to CA (cysteamine hydrochloride).

The logP value indicates that cysteamine hydrochloride (CA) is lipophilic and more accessible to the location of hydrophobic proteins inside the hair (octamer/microfibril).

Cysteamine hydrochloride (CA) because it contains active sulfhydryl, it breaks the disulfide bond in the hair, cystine is reduced to cysteine containing sulfhydryl, the hair becomes soft, bent and deformed with the hair curler, and then oxidized by oxidizing agent to make it soft to achieve a better curling effect. Its disadvantage is that it requires high purity, has a special smell, and has a stimulating effect on the skin. Because it is irritating to the skin, the Japanese pharmaceutical law stipulates that CA is in a low concentration specification (often configured in a neutral low alkali more), because of its special specification configuration, so that the hair burden is lower, so that the hair is more soft and healthy!

The reduction effect of cysteamine hydrochloride (CA) is higher than that of thioglycollic acid, so it shows better curling effect in curling operation. Compared with the same high PH and high concentration of thioglycollic acid, the biggest advantage of using cysteamine hydrochloride (CA) curly hair is that it does not need to be heated for a long time, and the curl degree of 5 minutes with a highly alkaline and high concentration cysteamine hydrochloride perm is equivalent to the effect of using thioglycollic acid for 15 minutes.

Cysteamine hydrochloride is a versatile compound with active chemical properties and can form a stable complex, which plays a key role in the functionality of hair perms. It has good film formation and high chemical activity, can form a stable cross-linked structure with the keratin of hair, change the structure of hair, so as to achieve the effect of perm.

Cysteamine hydrochloride perm in the process of perm, its main function is to provide a new crosslinking agent, and the keratin of the hair to form a more stable crosslinking structure, change the curl of the hair. Compared with other hair perms, its advantage is that it has little damage to the hair, and the effect of perm is natural and long-lasting.