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The mechanism and role of vitamin C in collagen synthesis

2025-06-26

1、 Core mechanism of action

Hydroxylation reaction catalysis

Vitamin C is a key coenzyme for collagen production, which promotes the hydroxylation of amino acid side chains in collagen molecules by catalyzing the hydroxylation reaction of proline and lysine, forming a stable triple helix structure.

Hydroxylated collagen has stronger mechanical strength and stability, which can effectively maintain the elasticity and toughness of tissues such as skin, bones, and blood vessels.

Antioxidant protection

Vitamin C neutralizes free radicals, reduces oxidative damage to collagen, and delays skin aging and increased vascular fragility caused by oxidative stress.

2、 Impact on organization and health

Skin Health

By promoting collagen synthesis, maintaining skin elasticity and firmness, reducing wrinkle formation, and accelerating wound healing.

Bones and joints

Collagen is an important component of bone matrix, and the involvement of vitamin C can enhance bone density, reduce the risk of fractures, and maintain the flexibility of joint cartilage.

Vascular function

Collagen provides support for the blood vessel wall, and vitamin C stabilizes its structure to prevent microvascular diseases such as vascular fragility and gum bleeding.

3、 Lack and Supplementary Suggestions

Lack of association with symptoms

Long term vitamin C deficiency can lead to collagen synthesis disorders and trigger scurvy, with typical symptoms including gum bleeding, skin bruising, and delayed wound healing.

Reasonable supplementary channels

Dietary source: Daily intake of fresh fruits and vegetables rich in vitamin C (such as kiwi, citrus, broccoli, etc.), it is recommended to eat raw or lightly processed to reduce nutrient loss.

Supplement use: Adults are recommended to consume 100mg per day. Special populations (such as pregnant women and postoperative patients) can adjust the dosage according to medical advice to avoid the risk of excessive intake leading to kidney stones and other complications.

http://86671.cn/ascorbic-acid-is-also-known-as-vitamin/

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